141 research outputs found
1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Kumla, Decha, Sousa, Emilia, Marengo, Alessia, Dethoup, Tida, Pereira, A. J., Gales, Luís, Freitas-Silva, Joana, Costa, Paulo M., Mistry, Sharad, Silva, Artur M.S., Kijjoa, Anake (2021): 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity. Phytochemistry (112575) 181: 1-15, DOI: 10.1016/j.phytochem.2020.112575, URL: http://dx.doi.org/10.1016/j.phytochem.2020.11257
Fig. 5 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Fig. 5. ORTEP view of 6.Published as part of Kumla, Decha, Sousa, Emilia, Marengo, Alessia, Dethoup, Tida, Pereira, A. J., Gales, Luís, Freitas-Silva, Joana, Costa, Paulo M., Mistry, Sharad, Silva, Artur M.S. & Kijjoa, Anake, 2021, 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity, pp. 1-15 in Phytochemistry (112575) 181 on page 6, DOI: 10.1016/j.phytochem.2020.112575, http://zenodo.org/record/829091
Scheme 2 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Scheme 2. Proposed mechanism for the formation of the spiropyran ring in 7.Published as part of Kumla, Decha, Sousa, Emilia, Marengo, Alessia, Dethoup, Tida, Pereira, A. J., Gales, Luís, Freitas-Silva, Joana, Costa, Paulo M., Mistry, Sharad, Silva, Artur M.S. & Kijjoa, Anake, 2021, 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity, pp. 1-15 in Phytochemistry (112575) 181 on page 10, DOI: 10.1016/j.phytochem.2020.112575, http://zenodo.org/record/829091
Fig. 4 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Fig. 4. ORTEP view of 5.Published as part of Kumla, Decha, Sousa, Emilia, Marengo, Alessia, Dethoup, Tida, Pereira, A. J., Gales, Luís, Freitas-Silva, Joana, Costa, Paulo M., Mistry, Sharad, Silva, Artur M.S. & Kijjoa, Anake, 2021, 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity, pp. 1-15 in Phytochemistry (112575) 181 on page 5, DOI: 10.1016/j.phytochem.2020.112575, http://zenodo.org/record/829091
Scheme 1 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Scheme 1. Proposed mechanism of the formation of the 1,3-dioxepine ring in 6.Published as part of Kumla, Decha, Sousa, Emilia, Marengo, Alessia, Dethoup, Tida, Pereira, A. J., Gales, Luís, Freitas-Silva, Joana, Costa, Paulo M., Mistry, Sharad, Silva, Artur M.S. & Kijjoa, Anake, 2021, 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity, pp. 1-15 in Phytochemistry (112575) 181 on page 8, DOI: 10.1016/j.phytochem.2020.112575, http://zenodo.org/record/829091
Fig. 1 in 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity
Fig. 1. Structures of specialised metabolites isolated from the cultures of the marine sponge-associated fungus Aspergillus elegans KUFA0015.Published as part of Kumla, Decha, Sousa, Emilia, Marengo, Alessia, Dethoup, Tida, Pereira, A. J., Gales, Luís, Freitas-Silva, Joana, Costa, Paulo M., Mistry, Sharad, Silva, Artur M.S. & Kijjoa, Anake, 2021, 1,3-Dioxepine and spiropyran derivatives of viomellein and other dimeric naphthopyranones from cultures of Aspergillus elegans KUFA0015 and their antibacterial activity, pp. 1-15 in Phytochemistry (112575) 181 on page 2, DOI: 10.1016/j.phytochem.2020.112575, http://zenodo.org/record/829091
Effects of Co-culturing with Live and Autoclaved Bacillus subtilis on Antagonistic Activity of Marine Fungi against Plant Pathogens
The co-culturing of the fungi with Bacillus subtilis resulted in increased antifungal activity of Eurotium
chevalieri and Emericella foveolata extracts but decreased the effects of Talaromyces tratensis and
T. stipitatus extracts. Meanwhile, the co-culturing of marine-derived fungi with autoclaved B. subtilis
resulted in decreased antifungal activity of E. foveolata, T. stipitatus and T. tratensis but slightly
increased activity of E. chevalieri. A significant effect of the co-culture of E. chevalieri and B. subtilis
resulted in an increased antifungal activity compared to the axenic cultures with complete inhibition
of mycelial growth of all the plant pathogens tested, whereas the extract from fungus alone displayed
percentage inhibition ranging from 33.11-100% at 10 g L-1 concentration. Overall, the effect of coculturing with live or autoclaved B. subtilis had positive, negative or no effect on the antifungal activities
of the tested marine-derive fungi against plant pathogens in vitro
Biological Control of Fruit Rot and Anthracnose of Postharvest Mango by Antagonistic Yeasts from Economic Crops Leaves
To select antagonistic yeasts for the control of fruit rot caused by Lasiodiplodia theobromae and anthracnose caused by Colletotrichum gloeosporioides in postharvest mango fruit, 307 yeast strains isolated from plant leaves were evaluated for their antagonistic activities against these two fungal pathogens in vitro. Torulaspora indica DMKU-RP31, T. indica DMKU-RP35 and Pseudozyma hubeiensis YE-21 were found to inhibit the growth of L. theobromae whereas only Papiliotrema aspenensis DMKU-SP67 inhibited the growth of C. gloeosporioides. Antagonistic mechanisms of these four antagonistic yeasts in vitro consisted of the production of antifungal volatile organic compounds (VOCs), biofilm formation and siderophore production. T. indica DMKU-RP35 was the most effective strain in controlling fruit rot on postharvest mango fruits. Its action was comparable to that of the fungicide, benomyl, reducing the disease severity by 82.4%, whereas benomyl revealed 87.5% reduction. P. aspenensis DMKU-SP67 reduced anthracnose severity by 94.1%, which was comparable to that of using benomyl (93.9%). The antifungal VOCs produced by these yeast strains also reduced the severity of these diseases on postharvest mango fruits but at lower rates than using yeast cells. Therefore, these antagonistic yeasts have the potential for use as biological control agents for the control of fruit rot and anthracnose diseases
Efficacy of berberine in controlling foliar rice disease
Berberine showed in vitro remarkable antifungal activity against rice pathogens including Bipolaris oryzae, Curvularia lunata, Pyricularia oryzae and Rhizoctonia solani with MIC values of 125 μg/mL. It showed potent preventative and curative activities in suppression of brown leaf spot disease of a susceptible Oryza sativa var. KDML 105 under greenhouse conditions. Berberine at 5 mg/mL showed effective brown leaf spot disease suppression in rice when applied before pathogen inoculation. It also showed higher fungicidal activity in suppression of brown leaf spot disease in plants aged 30 and 60 days than did difenoconazole and mancozeb when applied after pathogen inoculation. Moreover, berberine at 10 mg/mL significantly (P < 0.05) reduced the percentage of rice blast disease severity by 49.81%, which was similar to the action of difenoconazole and mancozeb when applied twice under field conditions. However, it showed low fungicidal activity against dirty particle disease, a complex disease of rice, under field conditions when compared with synthetic fungicides. These results indicated that berberine is a promising bioactive compound which may be developed as a lead compound in a new fungicide to control brown leaf spot and blast diseases of rice
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