1,721,036 research outputs found

    "Malformazioni anorettali"

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    Le malformazioni anorettali sono una patologia spesso ingrata e foriera di sequele per il chirurgo pediatra. per questo, nel tempo si sono perfezionate tecniche chirurgiche e si sono utilizzati strumenti per la maglificazione del campo operatorio innovazioni tecniche che hanno comportato un considerevole miglioramento dei risultati . Nonostante ciò, il paziente con malformazione anorettale resta un paziente complesso, per la cui gestione è necessaria la collaborazione di diversi specialisti che seguono il piccolo durante le varie fasi di crescita

    "Atresia dell'esofago"

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    l'Atresia esofagea rappresenta per il chirurgo pediatra la patologia per antonomasia, che necessita, come presupposto essenziale di guarigione, di un supporto anestesiologico-rianimatorio avanzato. La prognosi è migliorata notevolmente negli ultimi anni grazie all'approccio multidisciplinare dei pazienti e alle novità chirurgiche, che permettono ai piccoli pazienti di avere una qualità di vita ottimale, conservando il proprio viscere

    Model-based monitoring of an intensified unit for continuous pharmaceutical filtration-drying

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    Active pharmaceutical ingredient (API) separation from synthesis and crystallization mother liquors is typically carried out in pharmaceutical manufacturing through filtration and drying. These steps are of utmost importance, as impurities herein retained will inevitably end up in the drug product. Recently, a novel carousel has been developed for carrying out filtration and drying in a continuous intensified fashion. The unit represents a step forward with respect to traditional batch filtration and drying, as continuous operation can reduce the variability of the product quality. However, the occurrence of faults compromising product compliance can be assessed only upon discharge of the final cake of API crystals, when its purity can be measured. In this work, we develop a modelbased monitoring system for the unit, based on state and parameter estimation. The implemented monitoring system succeeds in tracking the product critical quality attributes (CQAs), and in detecting common faults for the carousel, such as sudden variations of the feed attributes

    Secondary Omental Torsion as a Rare Cause of Acute Abdomen in a Child and the Advantages of Laparoscopic Approach

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    Omental torsion is an underdiagnosed cause of acute abdomen in children. Most cases occur in adults, with only 15% presenting in children. It is estimated that omental infarct is found in approximately 0.1 to 0.5% of children undergoing operations for appendicitis. It may present with various signs and symptoms, although the clinical presentation usually mimics that of acute appendicitis. Definitive diagnosis is often established during surgery. We report a case of a 9-year-old boy who came to our attention for acute abdomen. We performed a laparoscopy-assisted procedure suspecting acute appendicitis. We therefore identified a secondary omental torsion associated with patency of the right inguinal duct and herniated omentum. Laparoscopy allowed a correct diagnosis and therapy
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