122,199 research outputs found
[Letter from W. R. Derr to T. N. Carswell - August 28, 1942]
No full textA letter written to Mr. T. N. Carswell, Abilene, Texas, from W. R. Derr, Pastor, First Baptist Church, Ralls, Texas, dated August 28, 1942. Derr assures Carswell that the liquor question will be presented to their association
Derr, William - carpenter
No full textA photograph of William Derr, carpenter and oil lamp man at the Salt Lake Theate
dERR binds to dHIFa and is essential for hypoxic survival.
No full text<p>(A) GST-pulldown experiment showing GST-fused dERR LBD association with full-length dHIFa, which is diminished when the final 11 amino acids of the LBD are deleted (ΔAF-2). Similarly, when the LXXLL motif in dHIFa is mutated, binding with the ERR LBD and ΔAF-2 proteins is lessened, but not eliminated when compared to GST alone. (B) <i>dERR</i> mutant animals are sensitive to H exposure and fail to successfully progress to the molt when challenged with 4% O<sub>2</sub>. Shown also are the results of <i>w<sup>1118</sup></i> animals and <i>sima</i> mutants. The L1 stage takes ∼24 hrs to progress through in N at 25°C, but the allotted time was extended to 48 hrs to account for developmental delays that are caused by H treatment. For more details and additional data, see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003230#pgen.1003230.s009" target="_blank">Table S3</a>.</p
Post-Planting Maintenance of Early-Stage Reconstructed Prairies within Urban Parks of Illinois
No full textTallgrass prairies are diverse ecosystems spread across the Midwest. Due to human activities such as farming and urban development, these prairies are now rare in their authentic form. The focus of this study is on the tallgrass prairies of Southwest Illinois. Prairie conservation efforts have engaged in various reconstruction projects, aiming to encourage and reestablish lost tallgrass prairie ecosystems. The objective of this study was to evaluate the effect of post-planting maintenance methods on coverage and biodiversity of native and invasive species within early-stage reconstructed tallgrass prairies in urban parks of southern Illinois. Evaluated variables included: total and individual species cover, plant type category, plant classification, species diversity, and community evenness in relation to management methods of annual mowing, manual weeding, and biannual prescribed burning. Results show total percent cover by management method is nonsignificant, but cover by plant type category revealed forb and grass cover to be significant for manually weeded beds in comparison to biannually burned and annually mowed beds. Similarly, manually weeded beds promoted the highest cover by planted native species whereas cover by invasive species was highest within annually mowed treatment beds. In conclusion, results suggest future promotion of grass species across all observed prairie systems due to their lack of presence in relation to native forbs. Manual weeding was most influential on native species flourishment, and in combating invasive species in relation to other treatments. Although, manual weeding is not always efficient and successful alone as a maintenance practice, therefore the use of long-term adaptive techniques is recommended.MAL
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Super-Resolution Microscopy as a Tool for Counting Proteins in a Sub-Cellular Environment
No full textSuper-resolution microscopy, and in particular single molecule localization microscopy (such as stochastic optical reconstruction microscopy, STORM), offers a unique opportunity for quantifying protein copy numbers with nanoscale resolutio
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
No full textAbstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
Quantifying Protein Copy Number in Super Resolution Using an Imaging-Invariant Calibration
No full textThe use of super-resolution microscopy in recent years has revealed that proteins often form small assemblies inside cells and are organized in nanoclusters. However, determining the copy number of proteins within these nanoclusters constitutes a major challenge because of unknown labeling stoichiometries and complex fluorophore photophysics. We previously developed a DNA-origami-based calibration approach to extract protein copy number from super-resolution images. However, the applicability of this approach is limited by the fact that the calibration is dependent on the specific labeling and imaging conditions used in each experiment. Hence, the calibration must be repeated for each experimental condition, which is a formidable task. Here, using cells stably expressing dynein intermediate chain fused to green fluorescent protein (HeLa IC74 cells)as a reference sample, we demonstrate that the DNA-origami-based calibration data we previously generated can be extended to super-resolution images taken under different experimental conditions, enabling the quantification of any green-fluorescent-protein-fused protein of interest. To do so, we first quantified the copy number of dynein motors within nanoclusters in the cytosol and along the microtubules. Interestingly, this quantification showed that dynein motors form assemblies consisting of more than one motor, especially along microtubules. This quantification enabled us to use the HeLa IC74 cells as a reference sample to calibrate and quantify protein copy number independently of labeling and imaging conditions, dramatically improving the versatility and applicability of our approach
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