4,277 research outputs found
A Mixed-Method Approach for Quantifying Illegal Fishing and Its Impact on an Endangered Fish Species
No full textIllegal harvest is recognized as a widespread problem in natural resource management. The use of multiple methods for quantifying illegal harvest has been widely recommended yet infrequently applied. We used a mixed-method approach to evaluate the extent, charac- ter, and motivations of illegal gillnet fishing in Lake Hovsgol National Park, Mongolia and its impact on the lake’s fish populations, especially that of the endangered endemic Hovsgol grayling (Thymallus nigrescens). Surveys for derelict fishing gear indicate that gillnet fishing is widespread and increasing and that fishers generally use 3–4 cm mesh gillnet. Interviews with resident herders and park rangers suggest that many residents fish for subsistence during the spring grayling spawning migration and that some residents fish commercially year-round. Interviewed herders and rangers generally agree that fish population sizes are decreasing but are divided on the causes and solutions. Biological monitoring indicates that the gillnet mesh sizes used by fishers efficiently target Hovsgol grayling. Of the five species sampled in the monitoring program, only burbot (Lota lota) showed a significant decrease in population abundance from 2009–2013. However, grayling, burbot, and roach (Rutilus ruti- lus) all showed significant declines in average body size, suggesting a negative fishing impact. Data-poor stock assessment methods suggest that the fishing effort equivalent to each resident family fishing 50-m of gillnet 11–15 nights per year would be sufficient to over- exploit the grayling population. Results from the derelict fishing gear survey and interviews suggest that this level of effort is not implausible. Overall, we demonstrate the ability for a mixed-method approach to effectively describe an illegal fishery and suggest that these methods be used to assess illegal fishing and its impacts in other protected areas.Peer reviewe
Clinical characteristics and predictors of gangrene in patients with systemic sclerosis and digital ulcers in the Digital Ulcer Outcome Registry: a prospective, observational cohort
Full text linkDisease Activity; Outcomes research; Systemic Sclerosis; Immunology and Allergy; Rheumatology; Immunology; Biochemistry, Genetics and Molecular Biology (all
Nailfold capillaroscopy in patients with systemic sclerosis-associated interstitial lung disease: a substudy of the SENSCIS trial
No full textElucidating the burden of recurrent and chronic digital ulcers in systemic sclerosis: long-term results from the DUO Registry
Full text linkOBJECTIVES: Digital ulcers (DUs) occur in up to half of patients with systemic sclerosis (SSc) and may lead to infection, gangrene and amputation with functional disability and reduced quality of life. This study has elucidated the burden of SSc-associated DUs through identification of four patient categories based on the pattern of DU recurrence over a 2-year observation period. METHODS: Patients with SSc-associated DUs enrolled in the Digital Ulcers Outcome Registry between 1 April 2008 and 19 November 2013, and with ≥2 years of observation and ≥3 follow-up visits during the observation period were analysed. Incident DU-associated complications were recorded during follow-up. Work and daily activity impairment were measured using a functional assessment questionnaire completed by patients after the observation period. Potential factors that could predict incident complications were identified in patients with chronic DUs. RESULTS: From 1459 patients, four DU occurrence categories were identified: 33.2% no-DU; 9.4% episodic; 46.2% recurrent; 11.2% chronic. During the observation period, patients from the chronic category had the highest rate of incident complications, highest work impairment and greatest need for help compared with the other categories. Independent factors associated with incident complications included gastrointestinal manifestations (OR 3.73, p=0.03) and previous soft tissue infection (OR 5.86, p=0.01). CONCLUSIONS: This proposed novel categorisation of patients with SSc-associated DUs based on the occurrence of DUs over time may help to identify patients in the clinic with a heavier DU burden who could benefit from more complex management to improve their functioning and quality of life
A Practical Approach to the Management of Digital Ulcers in Patients With Systemic Sclerosis: A Narrative Review
No full textIMPORTANCE: Digital ulcers (DUs) occurring on the fingers in patients with systemic sclerosis (SSc) are associated with substantial pain and disability and are often challenging to treat. However, careful clinical assessment and prompt intervention (wound bed management and systemic pharmacologic treatment) may modify the clinical course. OBJECTIVES: To provide a practical approach to the assessment and management of SSc-DUs and highlight unmet needs and research priorities. EVIDENCE REVIEW: A narrative review of the extant literature was undertaken to provide a broad overview of current knowledge and augmented by expert opinion. FINDINGS: Half of the patients with SSc have a history of DUs, and there is a point of prevalence of approximately 10%. Digital ulcers are often very painful and affect all aspects of physical, social, and family life as well as occupation. Digital ulcers are associated with a severe disease course. Systemic sclerosis DUs, particularly those occurring on the fingertips, represent a vascular ischemic complication, although other etiopathogenic factors play an important role. To guide management, a structured clinical approach is required, including DU definition, classification, and categorization. Digital ulcers require a multidisciplinary approach with close cooperation between physicians and specialist nursing and other allied health professionals to guarantee the appropriate treatment and provide patient education. Local wound bed management is necessary for all DUs and is combined with systemic (pharmacologic) treatments. When treating a DU, the clinician should actively review the therapeutic strategy to prevent further DUs, including the level of systemic disease control, and monitor closely for the development of DU complications, including infection and progression to gangrene. Despite a wide available therapeutic armory, a number of unmet needs and challenges remain that that require resolution to optimize DU management. CONCLUSIONS AND RELEVANCE: A practical approach to DU management, including local wound bed management and systemic treatments, is useful. Digital ulcers are of interest to a broad range of dermatologists, rheumatologists, and other physicians providing care for patients with SSc. Careful clinical assessment and prompt intervention can substantially modify the clinical course of DUs in SSc
Christopher Dawson
No full textInspired with Jude P. Dougherty’s works in which he stresses the overruling importance of the classical, humanistic education and the central place and role of religion in the Western culture, the author presents Christopher Dawson’s analysis of the Western civilization and his demonstration of the central role of Christianity in it. The author traces the premises on which was based Dawson’s opinion that modern Western man might be absorbed by his technical inventions, to the point of losing his soul
BA21570_Khanna_Online_supplementary_data – Supplemental material for Patient perception of disease burden in diffuse cutaneous systemic sclerosis
No full textSupplemental material, BA21570_Khanna_Online_supplementary_data for Patient perception of disease burden in diffuse cutaneous systemic sclerosis by Dinesh Khanna, Yannick Allanore, Christopher P Denton, Marco Matucci-Cerinic, Janet Pope, Barbara Hinzmann, Siobhan Davies, Janethe de Oliveira Pena and Oliver Distler in Journal of Scleroderma and Related Disorders</p
sj-png-2-njn-10.1177_20571585241227583 - Supplemental material for Swedish nursing research: A bibliometric and content analysis revealing author and institute collaborations, impact, and topics
No full textSupplemental material, sj-png-2-njn-10.1177_20571585241227583 for Swedish nursing research: A bibliometric and content analysis revealing author and institute collaborations, impact, and topics by Christopher Holmberg in Nordic Journal of Nursing Research</p
sj-png-1-njn-10.1177_20571585241227583 - Supplemental material for Swedish nursing research: A bibliometric and content analysis revealing author and institute collaborations, impact, and topics
No full textSupplemental material, sj-png-1-njn-10.1177_20571585241227583 for Swedish nursing research: A bibliometric and content analysis revealing author and institute collaborations, impact, and topics by Christopher Holmberg in Nordic Journal of Nursing Research</p
sj-png-3-njn-10.1177_20571585241227583 - Supplemental material for Swedish nursing research: A bibliometric and content analysis revealing author and institute collaborations, impact, and topics
No full textSupplemental material, sj-png-3-njn-10.1177_20571585241227583 for Swedish nursing research: A bibliometric and content analysis revealing author and institute collaborations, impact, and topics by Christopher Holmberg in Nordic Journal of Nursing Research</p
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