1,721,039 research outputs found
Combined Robotic Transanal Transection Single-Stapled Technique in Ultralow Rectal Endometriosis Involvement Associated With Parametrial and Vaginal Infiltration
No full textObjective: To describe a combined robotic and transanal technique used to treat ultralow rectal endometriosis in a 36-yearold patient with multiple pelvic compartments, which was responsible for infertility, dyspareunia, left sciatic pain, and severe dyschezia. Design: Surgical video article. Setting: The achievement of a perfect bowel anastomosis in patients with low rectal endometriosis could be challenging owing to technical and anatomic limitations [1]. By allowing a right angle rectotomy with a single-stapled anastomosis, the transanal transection single-stapled technique overcomes these technical difficulties ensuring a good-quality anastomosis with an easier correction of postoperative anastomotic leakage when it occurs [2,3]. Interventions: The surgery starts by splitting the nodule in 3 components according to different anatomic structures involved (parametrium, vagina, and rectum). Parametrial and vaginal fragments are excised as previously described (Supplemental Videos 1) [4]. The rectal involvement is approached following several steps: isolation and cut of inferior mesenteric vessels (inferior mesenteric artery and inferior mesenteric vein) and left colic artery to obtain a proper colon mobilization; transanal rectotomy immediately below the lower limit of the nodule; extraction of the specimen through the anus (Supplemental Videos 2); proximal bowel segment transection 1 cm above the upper limit of the nodule; introduction of circular stapler anvil into the sigmoid colon; placement of 2 purse string to secure the anvil and at distal rectal cuff, respectively; connection of the anvil to the shoulder of circular stapler; stapler closing and firing with coloanal anastomosis formation; stapled line reinforcement by stitching; and integrity anastomosis test (Supplemental Videos 3). No preventive diverting stoma was performed in accordance with our policy [5]. Conclusions: Although no data are yet available in patients with endometriosis, the use of transanal transection single-stapled technique may be an interesting approach in patients with very low rectal endometriosis involvement. Journal of Minimally Invasive Gynecology (2024) 31, 267 - 268. (c) 2024 Published by Elsevier Inc. on behalf of AAGL
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Ingénierie tissulaire en chirurgie colorectale : du défect pariétal au remplacement d’organe : étude in vitro et in vivo
No full textTissue engineering is a new tool in colorectal surgery for the prevention and treatment of fistula and rectalsphincter substitution after surgery for resection. This work includes:1) The selection of the matrix component : in vivo, 2 matrices were compared in 16 rabbits: Group A, matrixof decellularized swine intestinal submucosa (SIS, BioDesign ®), or reference matrix; Group B, a three layersmatrix of Chitosan hydrogel, or new matrix. The animals were sacrificed at 4 and 8 weeks. At 8 weeks, earlierepithelial regeneration, better control of the inflammatory response with a lower fibrosis report and obtainingof some islets of smooth muscle cells are obtained in the B group.2) The conception of an optimal delivering cells system: in vitro, fibrin and Chitosan were combined accordingto different formulations for Select a composite gel fibrin-Chitosan, characterized by mechanical tests, viabilityand cellular proliferation and the study of its ultrastructure.3) Their combination: vivo, in lieu of a colonic wall defect, we compared, in 20 pigs, acellular Chtiosan matrixto Chitosan matrix cellularized by autologous stromal vascular fraction isolated and contained in the gelcomposite Chitosan-fibrin. At 8 weeks, a full mucosal recovery was observed in the 2 groups with recovery adintegrum of the colonic walls, including smooth muscle cells confirmed by immunohistochemistery. Thefiborsis ratio was significantly lower in the cellularized group (15% vs. 50%, p = 0, 01). Finally, a cellularizedmatrix of circumferential Chitosan has successfully implanted to replace a colonic defect of 2 cm in length in3 pigs success. With end points such as technical feasibility, matrix behavior and quality of tissueregeneration, Chitosan has a major interest for the Colorectal tissue regeneration.L’ingénierie tissulaire représente un nouvel outil en chirurgie colorectale pour la prévention et le traitementdes fistules et pour la substitution sphinctérienne et rectale après chirurgie d’exérèse. Ce travail comprend :1) La sélection de la composante matricielle : in vivo, en remplacement d’un défect de paroi colique, 2matrices ont été comparées chez 16 lapins : groupe A, matrice de sous-muqueuse intestinale de porcdécellularisée (SIS, BioDesign®), référente; groupe B, matrice de chitosane, innovante. Les animaux étaientsacrifiés à 4 et 8 semaines. A 8 semaines, une régénération épithéliale plus précoce, un meilleur contrôle dela réponse inflammatoire avec un rapport de fibrose plus faible et l’obtention de quelques îlots de cellulesmusculaires lisses sont obtenus dans le groupe B.2) La confection d’un gel de délivrance cellulaire: in vitro, fibrine et chitosane ont été combinés selondifférentes formulations pour sélectionner un gel composite fibrine-chitosane, caractérisé par des testsmécaniques, de viabilité et de prolifération cellulaires et l’étude de son ultrastructure.3) Leur combinaison : in vivo, en remplacement d’un défect de paroi colique, nous avons comparé chez 20porcs la matrice acellulaire de chitosane à la matrice cellularisée par la fraction stromale vasculaireautologue, isolée et contenue dans le gel composite fibrine-chitosane. A 8 semaines, un recouvrementmuqueux complet de la zone implantée était observé dans les 2 groupes avec une régénération ad integrumde la paroi colique, y compris des cellules musculaires lisses confirmées par immunohistochimie, et unrapport de fibrose significativement plus faible dans le groupe cellularisé (15% vs. 50%, p=0,01). Enfin, unematrice de chitosane circonférentielle cellularisée a remplacé un défect colique de 2 cm de longueur chez 3porcs avec succès.Avec les critères de jugement tels que faisabilité technique, comportement matriciel et qualité de larégénération tissulaire, le chitosane présente un intérêt majeur pour la régénération tissulaire colorectale
Colorectal tissue engineering : from colonic wall defect to organ replacement
No full textL’ingénierie tissulaire représente un nouvel outil en chirurgie colorectale pour la prévention et le traitementdes fistules et pour la substitution sphinctérienne et rectale après chirurgie d’exérèse. Ce travail comprend :1) La sélection de la composante matricielle : in vivo, en remplacement d’un défect de paroi colique, 2matrices ont été comparées chez 16 lapins : groupe A, matrice de sous-muqueuse intestinale de porcdécellularisée (SIS, BioDesign®), référente; groupe B, matrice de chitosane, innovante. Les animaux étaientsacrifiés à 4 et 8 semaines. A 8 semaines, une régénération épithéliale plus précoce, un meilleur contrôle dela réponse inflammatoire avec un rapport de fibrose plus faible et l’obtention de quelques îlots de cellulesmusculaires lisses sont obtenus dans le groupe B.2) La confection d’un gel de délivrance cellulaire: in vitro, fibrine et chitosane ont été combinés selondifférentes formulations pour sélectionner un gel composite fibrine-chitosane, caractérisé par des testsmécaniques, de viabilité et de prolifération cellulaires et l’étude de son ultrastructure.3) Leur combinaison : in vivo, en remplacement d’un défect de paroi colique, nous avons comparé chez 20porcs la matrice acellulaire de chitosane à la matrice cellularisée par la fraction stromale vasculaireautologue, isolée et contenue dans le gel composite fibrine-chitosane. A 8 semaines, un recouvrementmuqueux complet de la zone implantée était observé dans les 2 groupes avec une régénération ad integrumde la paroi colique, y compris des cellules musculaires lisses confirmées par immunohistochimie, et unrapport de fibrose significativement plus faible dans le groupe cellularisé (15% vs. 50%, p=0,01). Enfin, unematrice de chitosane circonférentielle cellularisée a remplacé un défect colique de 2 cm de longueur chez 3porcs avec succès.Avec les critères de jugement tels que faisabilité technique, comportement matriciel et qualité de larégénération tissulaire, le chitosane présente un intérêt majeur pour la régénération tissulaire colorectale.Tissue engineering is a new tool in colorectal surgery for the prevention and treatment of fistula and rectalsphincter substitution after surgery for resection. This work includes:1) The selection of the matrix component : in vivo, 2 matrices were compared in 16 rabbits: Group A, matrixof decellularized swine intestinal submucosa (SIS, BioDesign ®), or reference matrix; Group B, a three layersmatrix of Chitosan hydrogel, or new matrix. The animals were sacrificed at 4 and 8 weeks. At 8 weeks, earlierepithelial regeneration, better control of the inflammatory response with a lower fibrosis report and obtainingof some islets of smooth muscle cells are obtained in the B group.2) The conception of an optimal delivering cells system: in vitro, fibrin and Chitosan were combined accordingto different formulations for Select a composite gel fibrin-Chitosan, characterized by mechanical tests, viabilityand cellular proliferation and the study of its ultrastructure.3) Their combination: vivo, in lieu of a colonic wall defect, we compared, in 20 pigs, acellular Chtiosan matrixto Chitosan matrix cellularized by autologous stromal vascular fraction isolated and contained in the gelcomposite Chitosan-fibrin. At 8 weeks, a full mucosal recovery was observed in the 2 groups with recovery adintegrum of the colonic walls, including smooth muscle cells confirmed by immunohistochemistery. Thefiborsis ratio was significantly lower in the cellularized group (15% vs. 50%, p = 0, 01). Finally, a cellularizedmatrix of circumferential Chitosan has successfully implanted to replace a colonic defect of 2 cm in length in3 pigs success. With end points such as technical feasibility, matrix behavior and quality of tissueregeneration, Chitosan has a major interest for the Colorectal tissue regeneration
Colorectal tissue engineering : from colonic wall defect to organ replacement
No full textL’ingénierie tissulaire représente un nouvel outil en chirurgie colorectale pour la prévention et le traitementdes fistules et pour la substitution sphinctérienne et rectale après chirurgie d’exérèse. Ce travail comprend :1) La sélection de la composante matricielle : in vivo, en remplacement d’un défect de paroi colique, 2matrices ont été comparées chez 16 lapins : groupe A, matrice de sous-muqueuse intestinale de porcdécellularisée (SIS, BioDesign®), référente; groupe B, matrice de chitosane, innovante. Les animaux étaientsacrifiés à 4 et 8 semaines. A 8 semaines, une régénération épithéliale plus précoce, un meilleur contrôle dela réponse inflammatoire avec un rapport de fibrose plus faible et l’obtention de quelques îlots de cellulesmusculaires lisses sont obtenus dans le groupe B.2) La confection d’un gel de délivrance cellulaire: in vitro, fibrine et chitosane ont été combinés selondifférentes formulations pour sélectionner un gel composite fibrine-chitosane, caractérisé par des testsmécaniques, de viabilité et de prolifération cellulaires et l’étude de son ultrastructure.3) Leur combinaison : in vivo, en remplacement d’un défect de paroi colique, nous avons comparé chez 20porcs la matrice acellulaire de chitosane à la matrice cellularisée par la fraction stromale vasculaireautologue, isolée et contenue dans le gel composite fibrine-chitosane. A 8 semaines, un recouvrementmuqueux complet de la zone implantée était observé dans les 2 groupes avec une régénération ad integrumde la paroi colique, y compris des cellules musculaires lisses confirmées par immunohistochimie, et unrapport de fibrose significativement plus faible dans le groupe cellularisé (15% vs. 50%, p=0,01). Enfin, unematrice de chitosane circonférentielle cellularisée a remplacé un défect colique de 2 cm de longueur chez 3porcs avec succès.Avec les critères de jugement tels que faisabilité technique, comportement matriciel et qualité de larégénération tissulaire, le chitosane présente un intérêt majeur pour la régénération tissulaire colorectale.Tissue engineering is a new tool in colorectal surgery for the prevention and treatment of fistula and rectalsphincter substitution after surgery for resection. This work includes:1) The selection of the matrix component : in vivo, 2 matrices were compared in 16 rabbits: Group A, matrixof decellularized swine intestinal submucosa (SIS, BioDesign ®), or reference matrix; Group B, a three layersmatrix of Chitosan hydrogel, or new matrix. The animals were sacrificed at 4 and 8 weeks. At 8 weeks, earlierepithelial regeneration, better control of the inflammatory response with a lower fibrosis report and obtainingof some islets of smooth muscle cells are obtained in the B group.2) The conception of an optimal delivering cells system: in vitro, fibrin and Chitosan were combined accordingto different formulations for Select a composite gel fibrin-Chitosan, characterized by mechanical tests, viabilityand cellular proliferation and the study of its ultrastructure.3) Their combination: vivo, in lieu of a colonic wall defect, we compared, in 20 pigs, acellular Chtiosan matrixto Chitosan matrix cellularized by autologous stromal vascular fraction isolated and contained in the gelcomposite Chitosan-fibrin. At 8 weeks, a full mucosal recovery was observed in the 2 groups with recovery adintegrum of the colonic walls, including smooth muscle cells confirmed by immunohistochemistery. Thefiborsis ratio was significantly lower in the cellularized group (15% vs. 50%, p = 0, 01). Finally, a cellularizedmatrix of circumferential Chitosan has successfully implanted to replace a colonic defect of 2 cm in length in3 pigs success. With end points such as technical feasibility, matrix behavior and quality of tissueregeneration, Chitosan has a major interest for the Colorectal tissue regeneration
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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