922 research outputs found
Rationalisation of UMT Operation in Conurbation Chomutov-Jirkov
No full textNázev práce:Racionalizace provozu MHD v souměstí Chomutov-Jirkov
Autor: Alena Zadáková
Obor: Management a ekonomika dopravy a telekomunikací
Druh práce: Bakalářská práce
Vedoucí práce:doc. Ing. Josef Volek CSc.
Fakulta dopravní ČVUT v PrazeName of Thesis: Racionalisation of UMT Operation in Conurbation Chomutov-Jirkov
Author: Alena Zadáková
Department: Management and Economics of Transportation and Telecommunications
Type of Thesis: Bachelor Thesis
Thesis Supervisor: doc. Ing. Josef Volek CSc.
Faculty of Transportation Science
Alena Mornstajnova?s language and the style of her novels
No full textThis bachelor thesis deals with the language analysis of all novels by Alena Mornštajnová published so far. They include the following novels: Slepá mapa, Hotýlek, Hana, and Tiché roky. The author is understood to be a phenomenon of current literature. The thesis consists of two main parts - a theoretical one and a practical one. The first part inspects not only the characteristics of artistic functional style, but also the author´s biography. The practical part is divided into three plans: a thematic one, composition one and a linguistic one. The greatest attention is dedicated to the last plan. It examines language resources from the perspective of individual layers, which are the phonetic, morphological, lexical or syntactic layer. The objective of this bachelor thesis is to find out what changes language resources in the individual works by Alena Mornštajnová have gone through
Alena alena Gyulai & Saldaitis & Zilli 2019, sp. n.
No full textAlena alena sp. n. (Figs 1–4, 9, 10, 14, 15) Type material. Holotype (Figs 1, 9): male, China, W Sichuan, Shaluli Shan, 40 km NW from Daocheng, 4060 m, N29°17.401′, E100°05.068′, 16–17.IX.2017, leg. Saldaitis, slide no. PGY4894, coll. PGM, later to be deposited in the HNHM. Paratypes (Figs 2–4, 10, 13, 14): 4 males and 9 females, same data as in the holotype, slide nos. PGY 4930m, PGY4899f (colls ASV, AFM & PGM / HNHM); 1 female, China, W-Sichuan, W. Bamei Mts., 3750m, 10.VIII.2005, leg. S. Murzin, slide no. AZ1854f (coll. PGM / HNHM). Diagnosis. As noted above under the generic description, all superficially similar species to Alena alena sp. n. are unrelated and can be promptly differentiated by their structural features (Figs 11–13, 16–18). In addition, Metopiora sanguinata (T.P. Lucas, 1893) also shows a pink band longitudinally crossing the forewing all through the middle (Fig. 8), which does not occur in the new species. Description (Figs 1–4). Wingspan 27–31 mm (holotypus 28 mm), length of forewing 13–15 mm (N = 14). Head and thorax whitish-pale straw-coloured, irregularly suffused with pink, particularly on legs; labial palpus pale brown-tipped, antenna pale ochre. Forewing with feebly acute apex, ground colour straw, with pink suffusion all along costal, anal and terminal edges, narrowest along the latter; fringe pink; hindwing straw-coloured also, with feeble brown irroration on disc and along veins, and fringe varying from straw to whitish-pale pink. Wing undersides patternless, with extensive dark grey suffusion on forewing. Male genitalia (Figs 9, 10). Overall configuration as in generic diagnosis. Tegumen dome-shaped, vinculum Vshaped with voluminous, broadly rounded saccus; valva of approximately uniform width, with distinctly concave costa, sacculus broad and elongated, clavus indistinct, costal plate broad, strongly sclerotized; clasper as in generic diagnosis; cucullus evenly rounded, its setae dense and long. Uncus as in generic description. Juxta rhomboid, slightly bilobed superiorly and irregularly sclerotised inferiorly. Aedeagus slightly reclinate at middle, broadly rounded distally on right side, where few minute carinal spines are present, vesica sub-quadrate, terminal cornuti field arranged into a narrow stripe. Female genitalia (Figs 14, 15). Segment A8 well sclerotised, truncate cone-shaped and relatively short, firmly linked with posterior section of ductus bursae, apophyses anteriores relatively long and robust, ductus bursae of uniform width, conspicuously ridged, with posterior edge representing anterior lip of ostium bursae, joining with corpus bursae ventrally on posterior third, corpus bursae broadly ellipsoid, appendix bursae rugose. Intersegmental membrane A8–A9 short. Papillae anales typical for " Apameina ", broad and flat, shortly setose, albeit without distinct midventral rods, apophyses posteriores longer than anteriores, slightly thinner and with feebly arcuate tips. Variability. Variation has so far been observed in the degrees of extension of pink suffusion along costal edge of forewing, dark irroration on hindwing, development of distal process of clasper, length of uncus and relative dimensions of female genitalic structures. Biology and distribution. Series of males and females were all collected at light in August-September in remote parts of West Sichuan chinese province near Daocheng and Ba-Mei mountains of the Shaluli Shan range (Fig. 19). The new species was collected at altitudes ranging from 3,700 to 4,100 m in mixed forests dominated by various conifer trees and shrubs such as Rhododendron spp. All individuals have been attracted before midnight, with ambient temperature between 3–5°C. Presence of at least two spermatophores in each of the dissected females shows that they mated more than once. Etymology. The new species is named in honour of Alena Kazakevich (Lida, Belarus), for her deep understanding and support of the entomological activities of the second author. The name is a feminine noun in apposition. Remarks. A correct systematic placement of Alena alena gen. n., sp. n. will only be achieved following a thorough reassessment of the concepts for Apameina and Sesamiina. In fact, its lyriform ovipositor appears to be typical for Apameina, although the absence of evident midventral rods between its lobes is a shared similarity with Sesamiina, which have a sharply pointed conical ovipositor. Other similarities between A. alena and most sesamiine groups are the rough, somewhat puffy thoracic vestiture concealing the boundaries between the patagium, tegulae and notum, the absence of notal crests, the broad costa of the valva distally dilated into a plate, and the cucullus without a neck or corona (cf. Moyal & Le Rü, 2005; Moyal et al., 2011a, 2011b; Le Rü et al., 2015).Published as part of Gyulai, Peter, Saldaitis, Aidas & Zilli, Alberto, 2019, A new genus and species of Apameini (Lepidoptera: Noctuidae) from Sichuan (China), pp. 593-600 in Zootaxa 4545 (4) on pages 595-599, DOI: 10.11646/zootaxa.4545.4.10, http://zenodo.org/record/261826
Interview with Alena Ledeneva: To Control a Level of Informality You Need the Targeted Therapy of Informal Practices
No full textIn the interview, Professor Alena Ledeneva discusses her research experience, current projects, and plans, and essentially presents her own programme for studying the worlds of informal economies through context-sensitive comparative ethnographic analysis. Beginning in the mid-1990s with a PhD dissertation on the role of blat in the functioning of the planned Soviet economy, today this research programme forms the basis of a unique empirical project for compiling the Encyclopaedia of the Informal World, involving 223 scholars from various countries. The case database collected in the Encyclopaedia… describes national versions of particular shadow practices, includes a list of the latest sociological and anthropological literature for analysing such practices, and is freely accessible to researchers.
The interview makes it clear how sensitivity to the methodological challenges of ethnography allows the author to move from retrospective study of a local empirical phenomenon to theorising. The conceptual insights that Professor Ledeneva reaches help to evaluate the quality of liberal reforms, including anti-corruption measures. She shows that when rigidity and double standards lie behind the façade of formal institutions, informal practices simultaneously contribute to both the formation and the destruction of social systems. Until the conflict between rules imposed from above and the responses from below is properly accounted for in socio-political transformations, speaking about minimising corruption will remain very difficult
Alena Slezáková and her position in media. Biographical study
No full textThesis Alena Slezáková and her position in media. Biographical study deals with career of a journalist, who has witnessed during her activie years in media important events of Czech and Czechoslovakian history. Since the year 1964 she worked in Lidová demokracie, Lidové noviny, Mladá fronta DNES and magazines Naše rodina and Týden. In the year 1969 she was forbidden from entering parliament. She was allowed to return after Velvet Revolution, when she also started to work on education of young and beginning journalists. In the end of her career, right before she retired, she became a book reviewer. This biographical study uses method of oral history, which means that author of this thesis interviewed Alena Slezáková regularly. It also uses method of qualitative content analysis of her texts, that informed about events in politics and society in Czech Republic and Czechoslovakia. Thesis also mentions important historic affairs, so the life and work of Slezáková can me contextualized. Aim of this thesis was not only to describe life of Alena Slezáková but also to outline transformations in media she witnessed - censorship and its dissolution, new media law and transformation of party's press. Part of this thesis are also two hypotheses which were confirmed. During the research it was shown that events..
Relevant genetic variants are common in women with pregnancy and lactation-associated osteoporosis (PLO) and predispose to more severe clinical manifestations
No full textPregnancy and lactation-associated osteoporosis (PLO) is a rare skeletal disorder characterized by early-onset osteoporosis typically manifestating with vertebral compression fractures or transient osteoporosis of the hip. We hypothesized that genetic variants may play a role in the development of PLO. This study aimed to analyze the presence of genetic variants and a potential association with the clinical presentation in PLO. 42 women with PLO were included from 2013 to 2019 in a multicenter study in Germany. All cases underwent comprehensive genetic analysis based on a custom-designed gene panel including genes relevant for skeletal disorders. The skeletal status was assessed using dual-energy X-ray absorptiometry (DXA). Subgroups were further analyzed by serum bone turnover markers (n = 31) and high-resolution peripheral computed tomography (HR-pQCT; n = 23). We detected relevant genetic variants in 21 women (50%), with LRP5, WNT1 and COL1A1/A2 being the most commonly involved genes. The mean number of vertebral compression fractures was 3.3 ± 3.4 per case with a significantly higher occurrence in the subgroup with genetic variants (4.8 ± 3.7 vs. 1.8 ± 2.3, p = 0.02). Among the total cohort, DXA Z-scores were significantly lower at the lumbar spine compared to the femoral neck (p = 0.002). HR-pQCT revealed a pronounced reduction of trabecular and cortical thickness, while trabecular number was within the reference range. Eighteen women (43%) received a bone-specific therapy (primarily teriparatide). Overall, a steep increase in bone mass (+37.7%) was observed after 3 years. In conclusion, pregnancy and lactation represent skeletal risk factors, which may unmask hereditary bone disorders leading to PLO. These cases were affected more severely. Nevertheless, a timely diagnosis and adequate treatment can ensure a substantial recovery potential even without specific therapy. Patients with genetically induced low bone turnover (e.g.; LRP5, WNT1) may especially benefit from osteo-anabolic medication
Genetic Diagnostics in Routine Osteological Assessment of Adult Low Bone Mass Disorders
No full textAbstract Context Many different inherited and acquired conditions can result in premature bone fragility / low bone mass disorders (LBMD). Objective We aimed at elucidating the impact of genetic testing on differential diagnosis of adult LBMD and at defining clinical criteria for predicting monogenic forms. Methods Four clinical centers broadly recruited a cohort of 394 unrelated adult women before menopause and men younger than 55 years with a bone mineral density (BMD) Z-score <-2.0, and/or pathological fractures. After exclusion of secondary causes or unequivocal clinical/biochemical hallmarks of monogenic LBMD all participants were genotyped by targeted next-generation sequencing Results In total 20.8% of the participants carried rare disease-causing variants (DCV) in genes known to cause osteogenesis imperfecta (COL1A1, COL1A2), hypophosphatasia (ALPL), and early-onset osteoporosis (LRP5, PLS3, and WNT1). In addition, we identified rare DCV in ENPP1, LMNA, NOTCH2, and ZNF469. Three individuals had autosomal recessive, 75 autosomal dominant, and four X-linked disorders. 9.7% of the participants harbored variants of unknown significance. A regression analysis revealed that the likelihood of detecting a DCV correlated with a positive family history of osteoporosis, peripheral fractures (>2), and a high normal BMI. In contrast, mutation frequencies did not correlate with age, prevalent vertebral fractures, BMD, or biochemical parameters. In individuals without monogenic disease-causing rare variants, common variants predisposing for low BMD, e.g. in LRP5, were overrepresented. Conclusion The overlapping spectra of monogenic adult LBMD can be easily disentangled by genetic testing and the proposed clinical criteria can help to maximize the diagnostic yield
Geometrie v reklamě
No full textNazov prace: Geomctria v reklamc - graficke zobrazovanie Autor: Lucia Quittnerova Katedra: Didaktika matematiky Veduci bakalarskej prace: PhDr. Alena Sarounova, CSc. Email veduceho: [email protected] Abstrakt: Tymto textom by som chcela ukazat' rozne moznosti grafickeho zobrazovania. Na zaciatku tcxtu som uviedla strucny historicky uvod. V d'alsej casti som citatel'a zoznamila s popisnou statistikou, ktorii som v texte pouzfvala. Rozdelenie grafov podfa typu je najobsiahlejsou casl'ou tejlo prace. Dolezity jc i vyber grafu, ktory spravne vystihnc informacie, ktore chceme zobrazit', preto som sa venovala i tcjto problematike. V d'alsej casti textu som ukazala, ako spravne zobrazit' graf a na ktore parametre sa zamerat'. Prfklady roznych typov klamnych, alebo zavadzajucich grafov a obrazkov som prczentovala v zavcrecnej casti prace. Kl'ucova slova: graficke zobrazovanie, typy grafov, zneuzitie grafov Title: Geometry in advertisement - graphs Author: Lucia Quittnerova Department: Didactics mathematics Supervisor: PhDr. Alena Sarounova, CSc. Supervisor's e-mail address: [email protected] Abstract: I would like to show various possibilities of displaying graphs. A short historical introduction opens the text. In its next part is the reader acquainted with the basic notions of descriptive...Nazov prace: Geomctria v reklamc - graficke zobrazovanie Autor: Lucia Quittnerova Katedra: Didaktika matematiky Veduci bakalarskej prace: PhDr. Alena Sarounova, CSc. Email veduceho: [email protected] Abstrakt: Tymto textom by som chcela ukazat' rozne moznosti grafickeho zobrazovania. Na zaciatku tcxtu som uviedla strucny historicky uvod. V d'alsej casti som citatel'a zoznamila s popisnou statistikou, ktorii som v texte pouzfvala. Rozdelenie grafov podfa typu je najobsiahlejsou casl'ou tejlo prace. Dolezity jc i vyber grafu, ktory spravne vystihnc informacie, ktore chceme zobrazit', preto som sa venovala i tcjto problematike. V d'alsej casti textu som ukazala, ako spravne zobrazit' graf a na ktore parametre sa zamerat'. Prfklady roznych typov klamnych, alebo zavadzajucich grafov a obrazkov som prczentovala v zavcrecnej casti prace. Kl'ucova slova: graficke zobrazovanie, typy grafov, zneuzitie grafov Title: Geometry in advertisement - graphs Author: Lucia Quittnerova Department: Didactics mathematics Supervisor: PhDr. Alena Sarounova, CSc. Supervisor's e-mail address: [email protected] Abstract: I would like to show various possibilities of displaying graphs. A short historical introduction opens the text. In its next part is the reader acquainted with the basic notions of descriptive...Katedra didaktiky matematikyDepartment of Mathematics EducationFaculty of Mathematics and PhysicsMatematicko-fyzikální fakult
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