1,721,282 research outputs found
La diagnostica per immagini nello studio degli angiomi iperplasici cutanei
No full textIntroduction
The hyperplasic hemangioma is a immature vases ball. The diagnosis asks for the study of the anatomical elements (mass, location, confinements) with the echography US and dynamic elements (vascular shanks and FAV fistula artery-venous) with the termography (TC termography to contact, TTD teletermography) and the ecography (ECD echo-color-Doppler, PD power-Doppler).
Purpose
they have been correlated the different techniques to individualize that in the diagnostic one of routine can define the clinical gravity and the evolution of the hemangioma.
Materials and Methods
have been included in the study, 52 males and 98 females, of 1-60 months with emangioma. The finds have been correlated TC, TTD, ECD and PD recorded at the beginning and at the end of therapeutic wait.
Results
The peduncles and the FAVs resulted were respectively present - to the beginning of the therapeutic wait to the PD in 142 and 107 cases, to the ECD in 135 and 102 cases, to the TTD in 134 and 101 cases, to the TC in 128 and 93 cases - at the end of wait to the PD in 25 and 21 cases, to the ECD and the TTD in 20 and 18 cases, to the TC in 15 and 13 cases. The correlations underline: p = 0,9929 between PD and TC, p = 0,9982 between PD eTTD, p = 0,9999 between ECD and TTD.
Discussion
the growth or the regression depend on the capacity of the vascular plot. The progression or the reduction of the lesion is underlined by the increase or by the diminution of the mass and of the number of the peduncles and of the FAVs. The results underline a decreasing sensibility of the investigations PD (100% of the cases), ECD (93,2203% of the cases), TTD (92,5423% of the cases) and TC (84,4067% of the cases).
Conclusions
The intensity of the vascular flow (number of fistulas and peduncles) allows to distinguish the natural history of the hemangioma in 5 evolutionary phases. Considering the correlations of Spearman the ECD can be the only necessary and enough investigation to the evaluation of the natural history of the cutaneous hemangioma of the infancy
Mono ADP-ribosylation inhibitors prevent inflammatory cytokine release in alveolar epithelial cells.
Full text linkA549, a type II alveolar epithelial cell line stimulated with LPS (10 mug/ml), released high levels of the inflammatory cytokines IL-6 and IL-8. Here, we have investigated whether ADP-ribosylation inhibitors block the LPS-triggered cytokine release in epithelial cells. When coincubating A549 with LPS and meta-iodobenzylguanidine or novobiocin, selective arginine-dependent ART-inhibitors, the release of IL-6 and IL-8 was inhibited in a concentration-dependent manner. This effect has been linked with the presence of a functionally active arginine ADP-ribosylating enzyme on the cell surface. To this aim, we amplified by RT-PCR the ART1 transcript and identified four ADP-ribosylated proteins likely substrate for ART1. The mechanism behind the cytokine inhibition in epithelial cells seems to be correlated with the presence of ART1, which behaves as an essential positive regulator of inflammatory cytokines. This novel observation indicates this enzyme as well as other novobiocin/MIBG sensitive ARTs as potential targets for the development of new therapeutic strategie
[Electroencephalographic research in schizophrenia. Review of the literature on research during wakefulness]
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Blood levels of S-adenosylmethionine in unmedicated schizophrenic and depressive patients
No full textL'effetto della tioridazina Retard nelle turbe comportamentali di disadattati scolastici
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La ricerca elettroencefalografica nella schizofrenia. Una revisione sintetica delle ricerche in veglia
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