1,721,067 research outputs found
QUETIAPINE AND MAJOR DEPRESSIVE DISORDER Severe adverse reactions associated with quetiapine
No full textVITAMIN D SUPPLEMENTS AND DISEASE PREVENTION Vitamin D supplements: don't forget depression and cognitive impairment
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Reversal of ethanol-induced hepatic steatosis and lipid peroxidation by taurine: A study in rats
No full textWhole blood folate, homocysteine in serum, and risk of first acute myocardial infarction
No full textSevere nightly hypotension with combination of antihypertensive medication and prothipendyl
No full textA 77 year old demented female with known arterial hypertension received 80 mg prothipendyl at 8 p. m. for sleep cycle regulation from the day of admission to a geriatric psychiatric ward. At first there seemed to be no adverse reactions. One week after adding amlodipine to the antihypertensive medication of ramipril, bisoprolol and hydrochlorothiazide because of arterial pressure of up to 260 mm Hg, she showed symptoms of disturbed cerebral perfusion with severe arterial hypotension of 60/40 mm Hg at 10 p. m., although daytime blood pressure measurements still yielded mostly hypertensive results. Satisfactory blood pressure regulation could only be achieved after prothipendyl was replaced by melperone. This case was registered by the AMSP (Arzneimittelsicherheit in der Psychiatrie - Drug Safety in Psychiatry) project and sheds light on the special problems of treating disorders of the sleep-wake-cycle with substances that have potential hypotensive side effects. Circadian sleep disorder of the irregular type is a frequent indication for geriatric psychiatric inpatient treatment of demented patients
Electric shock-like sensations (paresthesia) on venlafaxin discontinuation
No full textA hospitalized 24-year-old female patient with severe recurrent depression experienced very unpleasant electric shock-like paresthesias in the extremities. The symptoms lasted seven days and probably can be considered as a venlafaxin discontinuation syndrome. The symptoms relieved on reexposition with venlafaxin. This case report shall call attention to the basic relevance of discontinuation syndromes as adverse drug reactions. In addition, the clinical relevance of unusual paresthesias shall be emphasized
Pseudohallucinations after a single dose of zaleplon
No full textA former untreated 19 years old female patient developed, after been given a single dose of zaleplon, pseudohallucinations. They persisted for about 30 minutes and disappeared under a single dose of haloperidol and diazepine. Risk factors are not known
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