938 research outputs found
Occupation and bladder cancer in a hospital-based case-control study in Spain
No full textSamanic, C.M., Kogevinas, M., Silverman, D.T., Tardón, A., Serra, C., Malats, N., Real, F.X., Carrato, A., García-Closas, R., Sala, M., Lloreta, J., Rothman, N., Dosemeci, M
Asthma status is associated with decreased risk of aggressive urothelial bladder cancer
No full textRava, M., Czachorowski, M.J., Silverman, D., Márquez, M., Kishore, S., Tardón, A., Serra, C., García-Closas, M., Garcia-Closas, R., Carrato, A., Rothman, N., Real, F.X., Kogevinas, M., Malats, N
Maximum Distance Separable Codes and Arcs in Projective Spaces
No full textGiven any linear code over a finite field we show how can be
described in a transparent and geometrical way by using the associated
Bruen-Silverman code. Then, specializing to the case of MDS codes we use our
new approach to offer improvements to the main results currently available
concerning MDS extensions of linear MDS codes. We also sharply limit the
possibilities for constructing long non-linear MDS codes.Comment: 18 Pages; co-author added; some results updated; references adde
Temporal and spatial variability in speakers with Parkinson's Disease and Friedreich's Ataxia
No full textSpeech variability in groups of speakers with Parkinson's disease (PD) and with Friedreich's ataxia was compared with healthy controls. Speakers repeated the same phrase 20 times at one of two rates (fast or habitual). A non-linear analysis of variability was performed which used some of the principles behind the spatio-temporal index (STI). The STI usually employs variation in lip displacement over repetitions of the same utterance and a linear analysis of such signals is conducted to represent the combined variation in spatial and temporal control. When working with patients, audio measures (here we used speech energy) are preferred over kinematics ones as they are minimally disruptive to speech. Non-linear methods allow spatial variability to be estimated separately from temporal variability. The results are tentatively interpreted as showing that PD speakers were distinguished from healthy control speakers in spatial variability and ataxic speakers were distinguished from controls in temporal variability. These findings are consistent with the speech symptoms reported for these disorders. We conclude that the non-linear analysis using the speech energy measure is worth investigating further as it is potentially revealing of the differences underlying these two pathologies
Complex systems modeling for supply and demand in health and social care
No full textThis paper introduces a major new cross-disciplinary research project that looks at the UK health and social care system, as part of an ambitious, broader initiative to apply methods from complexity science to a range of key global challenges. This particular project aims to develop new, integrated models for the supply and demand of both health and social care, in the context of the societal change brought about by migration, mobility and the ageing population. We discuss the background to the work, and the broad way in which we intend to leverage complexity science. This is made more specific with a brief discussion on existing demographic models, and some examples of model-building in progress. We conclude with a glimpse into the subtly difficult problems of fostering such innovative interdisciplinarity
The Prevalence of Coffee Drinking Among Hospitalized and Population-Based Control Groups
No full textBladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes
No full textFigueroa, J.D., Malats, N., García-Closas, M., Real, F.X., Silverman, D., Kogevinas, M., Chanock, S., Welch, R., Dosemeci, M., Lan, Q., Tardón, A., Serra, C., Carrato, A., García-Closas, R., Castaño-Vinyals, G., Rothman, N
Response to intervention and reading outcomes
No full textSchools today continue to intensify the need to find effective interventions for students who are at risk for reading failure. Many have turned to a multi-tiered Response to Intervention (Rtl) model to provide reading interventions that will assist educators in improving reading outcomes. This one-group pretest-posttest design study examined the relationship between participation in Rtl reading intervention and reading outcomes among 117 students grouped in a Tier 2 reading intervention. Using Dynamic Indicators of Basic Early Literacy Skills (DIBELS) Next reading assessment composite scores, I analyzed reading change for three benchmark time periods for the 2012-2013 school year. Results from descriptive statistics, t-test measures, and a multiple regression analysis produced positive results. The majority of students (95%) participating in a Tier 2 reading intervention demonstrated statistically significant growth in reading outcomes with a reading change mean of 95.93 points regardless of their gender, English learner status, or free and reduced-price lunch status. Improvement in reading outcomes occurred in all three designated time periods measured. This quantitative study indicates that the majority of students who participated in Rtl reading interventions improved reading outcomes from the beginning of the year to the end of the year and made gains in closing the achievement gap for reading
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