1,721,277 research outputs found
Treatment of Hypopharingeal and Esophageal Squamous Cell Carcinoma
No full textMonografia sul Trattamento del Carcinoma Squamosi dell'Esofago sulla base dello stadio di malatti
Epidemiology of esophageal and hypopharyngeal squamous cell carcinoma
No full textThe incidence of esophageal squamous cell carcinoma (SCC) exceeds that of esophageal adenocarcinoma (AC) in all developing countries and in most developed countries, including Italy. By contrast, the incidence of AC has recently approached that of SCC in Scotland, the USA, and Israel.
Cancer of the hypopharynx is rather rare: in France it represents 0.40% of all cancers in men and 0.06% of those in women.
The most important risk factors for SCC of the esophagus and hypopharynx are excessive alcohol consumption, tobacco smoking, low socioeconomic status, and nutritional deficiencies
Gastrectomy with extended lymphadenectomy for primary treatment of gastric cancer (letter)
No full text
Treatment of esophago-gastric junction adenocarcinoma
No full textAIM: The incidence of Adenocarcinoma of the esophagogastric junction (EGJ) is increasing and its treatment is still debated, primarily because of the non-uniform definition of EGJ. MATERIALS AND METHODS: The most used classification of EGJ cancer was proposed by Siewert and it divides the EGJ in three regions: from 5 to I cm above the Z line (Siewert type I or esophageal Adenocarcinoma), from 1 over to 2 below the Z line (Siewert type II or real Cardia cancer) and from 2 below to 5 below the Z line (Siewert type III or proximal Gastric cancer diffused to Cardia). The neoplasia is defined type I, II or III depending on where is the center of the cancer. DISCUSSION: This classification did not show to be related to differences in prognosis and survival, but it has been used to guide the surgical strategy based on the site of the tumor. Criticism about this classification focuses mainly on the non-uniform treatment, in the current literature, of Siewert Type II cancer. CONCLUSION: From January 2010, a new definition of EGJ carcinoma has been introduced by TNM. This new de nition considers esophageal cancers all the ones whose centers falls inside a line drawn 5 cm below the Z line with invasion of the esophagus. This means that Siewert type I and II are now considered esophageal cancers, while type III can be esophageal or proximal gastric cancer depending if the esophagus is infiltrated or not. Criticism about this new definition rises on the border-line definition of former Siewert type III cancers
Surgery in Multimodal Treatment of Gastric Cancer
No full textTrattamento del Cancro dello stomaco con approccio multimodale. Note di tecnic
Classification of gastric carcinoma using the Goseki system provides prognostic information additional to TNM staging (letter)
No full textAuthors' reply: Response to induction therapy in oesophageal and cardia carcinoma using Mandard tumour regression grade or size of residual foci (letter)
No full textLette
Adenocarcinoma of the esophagogastric junction
No full textEsophagogastric junction (EGJ) cancer is, among solid cancers, the fastest growing tumor in terms of incidence in Western countries, and due to the lifestyle changes in developing and newly industrialized countries, this trend is expected to intensify worldwide. EGJ adenocarcinoma, however, is poorly defined: first because it is not an “organ disease” but a “zone disease,” and also because among EGJ cancers there can be included different diseases with different etiology and different biology. Eastern countries, led by Japan, taught us the correct management of gastric cancer and provided us guide- lines for the treatment of esophageal squamous cell carcinoma. However when we talk about EGJ adenocarcinoma, it is a separate entity and is more properly a Western reality; therefore, Western countries should systematize and give answers to the relevant issues this cancer raises, along the road to standardization. Europe has been leading the evolution of thought on EGJ carcinoma, especially thanks to Siewert and the German school, which cre- ated the classification that still is used as a guide by clinicians in therapeutic strategy planning. With the introduction of the latest version of the TNM, all EGJ cancers were defined as esophageal cancers, suggesting the possibility of a uniform treatment. In the era of tailored treatment and targeted therapy, we may wonder if what we already have is enough or if we need to go further on, especially considering the lack of homogeneity in the choice of multi- modal treatments according only to topography. I then decided that it was still necessary to concentrate just on this difficult cancer and, together with my co-workers Simone Giacopuzzi and Andrea Zanoni, I decided to write a book, which we hope will shed a little light on such a complex and current topic. To make this book more international, I invited to participate, in order to give their significant key to interpretation, also some surgeons of renowned importance in the field. I would like to thank them all deeply for their contributions. Based on the experience of the Italian Research Group for Gastric Cancer (GIRCG) and the European Chapter of IGCA, we hope that this collaboration will start to build an even closer international cooperation with the opportu- nity to create a European network on EGJ adenocarcinoma
- …
