9,439 research outputs found
Acid and base catalyzed Davis-Beirut reaction: Experimental and theoretical mechanistic studies and synthesis of novel 3-amino-2H-indazoles
No full textThe Davis-Beirut reaction, which provides an efficient synthesis of 2H-indazoles and, subsequently, indazolones, is shown to proceed rapidly from o-nitrosobenzaldehyde and primary amines under both acid and base catalysis. Experimental and theoretical evidence in support of a reaction mechanism is provided in which o-nitrosobenzylidine imine is a pivotal intermediate in this N,N-bond forming heterocyclization reaction. The Davis-Beirut reaction is also shown to effectively synthesize a number of novel 3-amino-2H-indazole derivatives. © 2012 Elsevier Ltd. All rights reserved.Avila B, 2011, ORG LETT, V13, P1060, DOI 10.1021-ol103108z; Bamberger E., 1918, CHEM BER, V51, P606; Butler JD, 2008, J ORG CHEM, V73, P234, DOI 10.1021-jo702067z; Cankarova N, 2010, ORG PREP PROCED INT, V42, P433, DOI 10.1080-00304948.2010.513898; Chen LJ, 1998, TETRAHEDRON LETT, V39, P5351, DOI 10.1016-S0040-4039(98)01068-5; Conrad W. E., 2011, ORG LETT, V13, P2141; Conrad WE, 2012, ORG LETT, V14, P3870, DOI 10.1021-ol3015804; De Angelis M, 2005, J MED CHEM, V48, P1132, DOI 10.1021-jm049223g; DEWAR MJS, 1984, J AM CHEM SOC, V106, P209, DOI 10.1021-ja00313a042; Donald MB, 2010, ORG LETT, V12, P2524, DOI 10.1021-ol100751n; Haddadin MJ, 2012, MINI-REV MED CHEM, V12, P1293; Huang LJ, 2006, BIOORGAN MED CHEM, V14, P528, DOI 10.1016-j.bmc.2005.08.032; Jung N., 2010, SCI SYNTH, V41, P613; Kurth MJ, 2005, J ORG CHEM, V70, P1060, DOI 10.1021-jo048153i; Mills AD, 2007, J COMB CHEM, V9, P171, DOI 10.1021-cc060109o; Mills AD, 2006, J ORG CHEM, V71, P2687, DOI 10.1021-jo0524831; Oakdale JS, 2009, ORG LETT, V11, P2760, DOI 10.1021-ol900891s; Schmidt A, 2008, EUR J ORG CHEM, P4073, DOI 10.1002-ejoc.200800227; Solano D. M., 2010, ORG SYNTH, V87, P339; Stadlbauer W., 2002, SCI SYNTH, V12, P227; Tantillo DJ, 2008, J PHYS ORG CHEM, V21, P561, DOI 10.1002-poc.1320; Williams A., 2000, CONCERTED ORGANIC BI; Wu CR, 2010, ORG LETT, V12, P2234, DOI 10.1021-ol100586r23
International Trade Law and Indigenous Peoples: A New Direction in Human Rights Advocacy?
No full textIndigenous peoples are increasingly frustrated by the lack of effective remedy in international human rights law and the convenience of the rhetoric of state sovereignty in relation to human rights as opposed to trade. Nascent Indigenous engagement with international trade fora such as the WTO may signal a new shift in international human rights advocacy for Indigenous peoples, writes Megan Davis
Self-compression of 4.9 µm pulses to sub-40 fs with 2 mJ energy in Zinc Sulfide
No full textNonlinear self-compression of few-cycle multi-mJ pulses at 4.9 µm in ZnS is presented. 80 fs input pulses are compressed to 37 fs with 2.1 mJ energy at a 1 kHz repetition rate. © 2024 The Author(s
Susceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))
No full textSusceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))</p
Susceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))
No full text Susceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671)) </p
Susceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))
No full textSusceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))</p
Susceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))
No full textSusceptibility ([k] (cm2/mJ)) calculation to determine LRV obtained per mJcm2 against black mold (Cladosporium halotolerans ATCC 10391 (NRRL 1671))</p
Claimed 2,1-benzisoxazoles are indazalones
No full text(Chemical Equation Presented) Claims, by two groups, to have prepared 2,1-benzisoxazole derivatives are corrected to show that the products are indazalones (5). In addition, a simple preparation of 3-oxysubstituted 2H-indazole, by an unrecognized method in the literature, is reported.ARAN VJ, 1997, TETRAHEDRON, V45, P129; Bamberger E., 1918, CHEM BER, V51, P606; Bjorsvik HR, 2004, J ORG CHEM, V69, P7720, DOI 10.1021-jo049102o; Boduszek B, 1997, TETRAHEDRON, V53, P11399, DOI 10.1016-S0040-4020(97)00721-7; Chen LJ, 1998, TETRAHEDRON LETT, V39, P5351, DOI 10.1016-S0040-4039(98)01068-5; HADDADIN MJ, UNPUB; ISHIKAWA F, 1980, CHEM PHARM BULL, V28, P1357; Stadlbauer W., 2002, SCI SYNTH, V12, P22721212
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