396 research outputs found

    DS_10.1177_0363546518759674 – Supplemental material for Nonsurgical Treatments of Patellar Tendinopathy: Multiple Injections of Platelet-Rich Plasma Are a Suitable Option: A Systematic Review and Meta-analysis

    No full text
    Supplemental material, DS_10.1177_0363546518759674 for Nonsurgical Treatments of Patellar Tendinopathy: Multiple Injections of Platelet-Rich Plasma Are a Suitable Option: A Systematic Review and Meta-analysis by Luca Andriolo, Sante Alessandro Altamura, Davide Reale, Christian Candrian, Stefano Zaffagnini, and Giuseppe Filardo in The American Journal of Sports Medicine</p

    Table-top combined scanning X-ray small angle scattering and transmission microscopies of lipid vesicles dispersed in free-standing gel

    No full text
    A mm thick free-standing gel containing lipid vesicles made of 2-oleoyl-1-palmitoyl-sn-glycero-3- phosphocholine (POPC) was studied by scanning Small Angle X-ray Scattering (SAXS) and X-ray Transmission (XT) microscopies. Raster scanning relatively large volumes, besides reducing the risk of radiation damage, allows signal integration, improving the signal-to-noise ratio (SNR), as well as high statistical significance of the dataset. The persistence of lipid vesicles in gel was demonstrated, while mapping their spatial distribution and concentration gradients. Information about lipid aggregation and packing, as well as about gel density gradients, was obtained. A posteriori confirmation of lipid presence in well-defined sample areas was obtained by studying the dried sample, featuring clear Bragg peaks from stacked bilayers. The comparison between wet and dry samples allowed it to be proved that lipids do not significantly migrate within the gel even upon drying, whereas bilayer curvature is lost by removing water, resulting in lipids packed in ordered lamellae. Suitable algorithms were successfully employed for enhancing transmission microscopy sensitivity to low absorbing objects, and allowing full SAXS intensity normalization as a general approach. In particular, data reduction includes normalization of the SAXS intensity against the local sample thickness derived from absorption contrast maps. The proposed study was demonstrated by a room-sized instrumentation, although equipped with a high brilliance X-ray micro-source, and is expected to be applicable to a wide variety of organic, inorganic, and multicomponent systems, including biomaterials. The employed routines for data reduction and microscopy, including Gaussian filter for contrast enhancement of low absorbing objects and a region growing segmentation algorithm to exclude no-sample regions, have been implemented and made freely available through the updated in-house developed software SUNBIM

    Noninterferometric rotational test of the continuous spontaneous localization model: Enhancement of the collapse noise through shape optimization

    No full text
    The continuous spontaneous localization (CSL) model is the most studied among collapse models, which describes the breakdown of the superposition principle for macroscopic systems. Here, we derive an upper bound on the parameters of the model by applying it to the rotational noise measured in a recent short-distance gravity experiment [Lee et al., Phys. Rev. Lett. 124, 101101 (2020)]. Specifically, considering the noise affecting the rotational motion, we found that despite being a tabletop experiment the bound is only one order of magnitude weaker than that from LIGO for the relevant values of the collapse parameter. Further, we analyze possible ways to optimize the shape of the test mass to enhance the collapse noise by several orders of magnitude and eventually derive stronger bounds that can address the unexplored region of the CSL parameters space

    Improved bounds on collapse models from rotational noise of the Laser Interferometer Space Antenna Pathfinder mission

    No full text
    We study spontaneous wave-function collapse models, which modify the Schrödinger equation with nonlinear and stochastic terms offering a solution to the quantum measurement problem. We find that constraints on the phenomenological parameters of the continuous spontaneous localization (CSL) model can be tightened using the recent analysis of the Laser Interferometer Space Antenna Pathfinder mission’s angular motion data. We derived a stronger constraint on the CSL model than previously achieved with translational motion. Additionally, we identify general conditions under which rotational measurements provide an advantage over translational ones in testing collapse models. These results enhance the experimental strategies for probing fundamental modifications of quantum mechanics

    “Ti regalerò fucili”. Ironia e saggezza nelle parodie del primo Eco

    No full text
    In his first works Umberto Eco reveals himself to be a multifaceted author, able to move easily from scientific essay to parody, one considered as the reverse or the negative of the other. There’s a relationship of specularity between the pieces of Diario minimo and the essays on mass culture of Apocalittici e integrati, which clearly emerges from a parody like Fenomenologia di Mike Bongiorno, where Eco literally destroys the popular figure of the anchorman with the excuse of describing it analytically. Yet parody in Eco, despite its corrosive force, does not have a moralistic or inquisitorial value, but a sceptical-ironic one: castigat more ridendo. It is an essay of “serious entertainment” that functions as an “extreme litmus test” to verify the validity of the cultural references of its time, both the “high” ones and those linked to mass culture. Diario minimo is crossed by a subtle pedagogical tension which, as Paolo Fabbri claims, “has the aim of transmitting a morality [...] based on an unsuspected common sense, but conveyed by a humorous and ironic form” (Fabbri 2010). Beyond the right to be irreverent which is invoked by the author on the back cover of the book there is not a need for “semiological guerrilla”, but a form of minimal wisdom that disguises itself as a playful spirit

    Relationship between nano/micro structure and physical properties of TiO2-sodium caseinate composite films

    No full text
    Films obtained by casting, starting from conventional emulsions (CE), nanoemulsions (NE) or their gels, which led to different structures, with the aim of explore the relationship between structure and physical properties, were prepared. Sodium caseinate was used as the matrix, glycerol as plasticizer, glucono-delta-lactone as acidulant to form the gels, and TiO2 nanoparticles as reinforcement to improve physical behavior. Structural characterization was performed by SAXS and WAXS (Small and Wide Angle X-ray Scattering, respectively), combined with confocal and scanning electron microscopy. The results demonstrate that the incorporation of the lipid phase does not notably modify the mechanical properties of the films compared to solution films. Films from NE were more stable against oil release than those from CE. Incorporation of TiO2 improved mechanical properties as measured by dynamical mechanical analysis (DMA) and uniaxial tensile tests. TiO2 macroscopic spatial distribution homogeneity and the nanostructure character of NE films were confirmed by mapping the q-dependent scattering intensity in scanning SAXS experiments. SAXS microscopies indicated a higher intrinsic homogeneity of NE films compared to CE films, independently of the TiO2 load. NE-films containing structures with smaller and more homogeneously distributed building blocks showed greater potential for food applications than the films prepared from sodium caseinate solutions, which are the best known films.Fil: Montes de Oca Avalos, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; ArgentinaFil: Altamura, Davide. Consiglio Nazionale delle Ricerche; ItaliaFil: Candal, Roberto Jorge. Universidad Nacional de San Martín. Instituto de Investigación en Ingeniería Ambiental; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Scattarella, Francesco. Consiglio Nazionale delle Ricerche; ItaliaFil: Siliqi, Dritan. Consiglio Nazionale delle Ricerche; ItaliaFil: Giannini, Cinzia. Consiglio Nazionale delle Ricerche; ItaliaFil: Herrera, Maria Lidia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Tecnología en Polímeros y Nanotecnología. Universidad de Buenos Aires. Facultad de Ingeniería. Instituto de Tecnología en Polímeros y Nanotecnología; Argentin

    Link budget analysis of bi-directional LEO and GEO optical feeder links advancing the beam wander model’s accuracy

    No full text
    Abstract The telecommunications of the future rely on the concept of a three-dimensional architecture able to integrate terrestrial and non-terrestrial networks with the goal to ensure a reliable and high-speed connectivity to users located anywhere. In this context, free space optical communications constitute a candidate technology for feeder links, thanks to their advantages in terms of bandwidth and achievable data rates. Nonetheless, due to the propagation impediments encountered by an optical beam travelling through atmosphere, flexible and accurate instruments able to support the design of optical feeder links are needed. Therefore, in this paper a link budget numerical tool able to meet these requirements is presented and the link budget analysis for real optical feeder links is performed demonstrating its prediction accuracy by means of the comparison with experimental results for both low Earth orbit and geostationary Earth orbit based configurations. Finally, the limits of the conventional beam wander model are analyzed and overcome
    corecore