4,634 research outputs found
Tettagalma Menon, new genus
No full text<i>Tettagalma</i> Menon, new genus <p> <b>Diagnosis.</b> Medium­sized (25 mm forewing length) tettigarctid; prominent costal margin; Rs with three branches; origin of MA branches proximal to nodal line; CuA strongly deflected anteriorly at nodal line; wide marginal membrane; marginal membrane bearing numerous, equidistant striae.</p> <p> <b>Etymology.</b> Genus­group name formed from a combination of <i>tetti</i> in reference to the family and <i>agalma</i> from the Greek present, gift, as the specimen was donated to the author.</p> <p> <b>Type locality and horizon.</b> Vicinity of Nova Olinda, Nova Olinda Member, Crato Formation.</p> <p> <b>Type species.</b> <i>Tettagalma striata</i> Menon new genus and species, by monotypy.</p>Published as part of <i>Menon, Federica, 2005, New record of Tettigarctidae (Insecta, Hemiptera, Cicadoidea) from the Lower Cretaceous of Brazil, pp. 53-58 in Zootaxa 1087</i> on page 54, DOI: <a href="http://zenodo.org/record/170508">10.5281/zenodo.170508</a>
Itolizumab – a humanized anti-CD6 monoclonal antibody with better side effects profile for the treatment of psoriasis [Corrigendum]
No full textMenon R, David BG. Clinical, Cosmetic and Investigational Dermatology. 2015;8:215–22.On page 215, please note correspondence should have been listed as: Roshni Menon, D II/17,JIPMER Campus, Dhanvanthri Nagar,Pondicherry, India 605006Tel +91 944 320 8140Email [email protected] page 215, the first sentence of the Introduction was “Psoriasis is a chronic inflammatory disease of the skin characterized by exacerbations and remissions affecting 1%–3% of the world’s population, and approximately 20% of patients have moderate to severe disease.1,2” however should have been “Psoriasis is a chronic inflammatory disease of the skin characterized by exacerbations and remissions affecting 1%–3% of the world’s population. Approximately 20% of patients have moderate to severe disease.1,2”On page 217, 219, and 221 the running header was “Itolizumab – aCD6 monoclonal antibody for the treatment of psoriasis” however should have been “Itolizumab – a humanized anti CD6 monoclonal antibody for the treatment of psoriasis”.On page 218, Table 1, the second column heading was listed as “Anand et al25 n=40 (moderate–severe psoriasis)” however should have been “Anand et al25 n=40/32 weeks (moderate–severe psoriasis)”.Read the original article 
AJMQ859076_Online_Appendices_CLN – Supplemental material for Experiential Learning Through Local Implementation of a National Chief Resident in Quality and Patient Safety Curriculum
No full textSupplemental material, AJMQ859076_Online_Appendices_CLN for Experiential Learning Through Local Implementation of a National Chief Resident in Quality and Patient Safety Curriculum by Matthew V. Ronan, Aravind Menon, Lakshman Swamy and David Thornton in American Journal of Medical Quality</p
Virtual Event - COVID-19: Implications for Global and Country-Level Food Security, Nutrition, and Poverty
No full textJohan Swinnen, David Laborde Debucquet, Xiaobo Zhang, Purnima Menon, and James Thurlow POLICY SEMINAR Virtual Event - COVID-19: Implications for Global and Country-Level Food Security, Nutrition, and Poverty APR 14, 2020 - 12:15 PM TO 01:15 PM ED
Reviews: Religion in Contemporary Drama (Sinead Crowe); Performing the Secular: Religion, Representation and Politics (Milija Gluhovic and Jisha Menon, eds.); The Theatre of the Occult Revival: Alternative Spiritual Performance from 1875 to the Present (Edmund B. Lingan)
No full textReviews of:Sinéad Crowe: Religion in Contemporary German Drama (Reviewed by David O’Donnell)Milija Gluhovic and Jisha Menon, eds: Performing the Secular: Religion, Representation and Politics (Review by Katharina Pewny)Edmund B. Lingan: The Theatre of the Occult Revival: Alternative Spiritual Performance from 1875 to the Present (Review by Leigh Kennicot)
Novel Dialogue 2.3: Because I Couldn't Be a Dancer: Sigrid Nunez and Tara Menon (JP)
No full textThe brilliant New York writer Sigrid Nunez's most recent novel is What Are You Going Through; her previous one, The Friend, (2018) won the National Book Award. She speaks with Tara Menon, of the Harvard English department, and author of a terrific article about Sigrid Nunez in the Sewanee Review. The conversation ranges widely and then plunges into depths. Because life is defined by grief and mourning, so too are my novels, says Nunez. She thinks her upbringing with immigrant parents who felt adrift from their homeland and her own "failure" as a dancer (recounted in her 1995 debut novel, A Feather on the Breath of God ) are the ferment from which her vocation as a writer arose. The question of genre is tossed around: "fictional memoir" perhaps, which gets confused (insultingly, Tara thinks!) with auto-fiction. But Sigrid is fascinated by establishing a reality that is entirely made-up ("not a single friend angry!"), yet also documentary in nature. Perhaps the best tag for her work is "essay novel": that allows one to do what Javier Marias calls "literary thinking." And there's a wonderfully non-Pavlovian answer to the treat question: sometimes you can just have the whiskey
Evolving Asian Power Balances and Alternate Conceptions for Building Regional Institutions
No full textThe paper aims to examine economic interdependence and balancing power politics, and their mixed implications for regional institution building in East Asia based on the concept of common security. By pointing out the gap between the violent conflict prediction and the stability and prosperity reality following the end of the Cold War, the paper gives analysis to the factors affecting the security relations in the region, including (i) the role of the US, (ii) the rise of the PRC, (iii) ASEAN's efforts at regional cooperation, the (iv) the PRC–Japan rivalry. The author concludes that economic interdependence and regional cooperation in Asia have constrained a power struggle from spiraling out of control, while open regionalism has become a reasonable approach to regional institution building. Finally, the paper makes policy recommendations with respect to principles and steps in moving to a new regional security order.East Asia; Regional Cooperation; Power Politics; Balance of Power; Regional Institutions; Common Security
A priori and a posteriori analysis of the hybrid two-level large-eddy simulation method for high Reynolds number complex flows
No full textWe present a priori and a posteriori analysis of the assumptions and predictions of the hybrid two-level large-eddy simulation (TLS-LES) method for high Reynolds number complex flows. The TLS-LES methodology is a multi-scale framework for simulation of turbulent flows in complex configurations at practically relevant Reynolds number. It additively combines the two-level simulation (TLS) model with a conventional large-eddy simulation (LES) approach by employing a static or dynamic blending function. In the present study, first we analyze the model assumptions employed by the TLS model to obtain the small-scale solution necessary for closure of the large-scale equations. Afterward, we analyze the large-scale and small-scale solutions to assess the predictive ability of the multi-scale framework for specific turbulence physics such as role of forward and backscatter of energy and presence of co- and counter-gradient diffusion. To perform these investigations, we consider cases with increasing degree of geometrical complexity, namely, flow in a periodic channel, flow past a bump placed on the lower surface of the channel and flow past a finite-span NACA0015 airfoil
Novel plant nuclear envelope-associated coiled-coil proteins
No full textThe nuclear envelope (NE) is a double lipid bilayer enclosing the eukaryotic genome. The metazoan nucleoskeleton includes the peripheral lamina and the internal nucleoskeleton. The lamina is composed of a network of intermediate filament (IF) proteins called lamins, as well as lamin- and/or chromatin-binding inner nuclear membrane (INM) proteins. The components of the metazoan lamina lack sequence homologues in plants. There is however evidence of a network of nuclear filamentous proteins underlying the NE. This study aims to characterise a novel family of NE-associated proteins (NEAP) in the model plant, Arabidopsis thaliana.
The family consists of four proteins, AtNEAP1-4 conserved in plants restricted to the angiosperm clade. Their expression is ubiquitous with up-regulation in embryo, inflorescence and guard cells. NEAP protein structure consists of extensive coiled-coil (CC) domains, followed by a nuclear localisation signal (NLS) and a C-terminal transmembrane (TM) domain. Confocal microscopy shows that fluorescent protein tagged NEAP proteins localise to the nuclear periphery as part of highly immobilised stable complexes. Domain deletion mutants confirm the presence of functional NLS and TM domains, while their CC nature causes insolubility under high ionic salt and Triton X-100 conditions similar to other IF-like proteins. AtNEAP2 and AtNEAP3 interact with themselves as well as with AtNEAP1 and each other. NEAP proteins also interact with the classical and mid-SUN domain families. NEAP proteins also cause mis-localisation of the plant nuclear matrix constituent protein 1 from the nuclear periphery to the nucleoplasm. An A. thaliana cDNA library screen identified a basic leucine zipper transcription factor (TF), AtbZIP18 as a novel interactor of AtNEAP1. This is a first description of a chromatin-binding protein partner of the plant INM.
Single and double NEAP knockout and knockdown mutants analysed displayed various defects in nuclear size, shape and positioning in different tissues. Therefore NEAP proteins appear to be involved in regulating nuclear morphology in plants. Thus as novel nuclear IF-like proteins that interact with a chromatin binding TF and have functions in regulating nuclear morphology, NEAP proteins are putative components of the plant lamina anchored at the INM
- …
