2,137 research outputs found
Paul Marchant and David Woessner Ross High School's 1981 Top Graduates
No full textRoss High School seniors Paul Marchant and David Woessner were recognized at the Annual Senior Awards Program for having the two highest grade point averages. Marchant is the son of Mr. and Mrs. Paul Marchant, 646 Sunset Lane, Fremont. Marchant also received the State DAR Good Citizens Test Award and a $10 prize for receiving the highest score among Ross Seniors
GENOMICS AND ENVIRONMENTAL REGULATION: SCIENCE, ETHICS, AND LAW
No full textPreface -- List of contributors -- Introduction: environmental policy in the age of genomics / Richard R. Sharp, Gary E. Marchant, and Jamie A. Grodsky -- Pt. I. Environmental policy perspectives -- 1. Toxicogenomics and environmental regulation / Gary E. Marchant -- 2. Addressing genomic needs at the U.S. Environmental Protection Agency / Kerry L. Dearfield, William H. Benson, Kathryn Gallagher, and Jeremy D. Johnson -- 3. Application of genomics for health and environmental safety of chemicals: an industry perspective / Richard D. Phillips -- 4. Toxicogenomics and the public interest: technical and sociopolitical challenges / John M. Balbus -- Pt. II. Legal perspectives -- 5. Challenges in applying toxicogenomic data in federal regulatory settings / Lynn L. Bergeson -- 6. Genetic data and toxic torts: intimations of statistical reductionism / Andrew Askland and Gary E. Marchant -- 7. Genomics and environmental justice: some preliminary thoughts / Gary E. Marchant and Jamie A. Grodsky -- 8. Setting air quality standards in the postgenomic era / Gary E. Marchant -- Pt. III. Occupational health perspectives -- 9. Genetics and workplace issues / Paul A. Schulte -- 10. Advances in human genome epidemiology: implications for occupational health and disease prevention / Marc Weinstein -- 11. Occupational health and discrimination issues raised by toxicogenomics in the workplace -- Mark A. Rothstein -- 12. Genetic susceptibility and radiological health and safety / Kenneth L. Mossman -- Pt. IV. Ethical and philosophical perspectives -- 13. Conceptual and normative dimensions of toxicogenomics / Andrea O. Smith and Jason Scott Robert -- 14. Enviromental disease, biomarkers, and the precautionary principle / David B. Resnik -- 15. Rights and the exceptionally vulnerable / James W. Nickel -- 16. (Almost) equal protection for genetically susceptible subpopulations: a hybrid regulatory-compensation proposal / Carl Cranor -- 17. Protecting people in spite of or thanks to the "veil of ignorance" / Adam M. Finkel -- Appendix: Executive summary of National Research Council Report, Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment -- Inde
Macquarie Island Stream Invertebrate Taxa Data Sheets; 2008 - 2016
No full textProgress Code: completedStatement: The scanned images are faint, but ticks (indicating presence of a taxa in a sample) are legible. Additional feint notes can be disregarded, these are additional notes made by R. Marchant during sample processing that relate to the general condition of the samples.<b>Purpose</b><br/>Provide a scanned copy of original hard copy, hand written, score sheets prepared by Richard Marchant as a record of replicate-level presence/absence data. Digitised data for 2008, 2010 and 2016 are entered as sum of five replicate samples for each site (values 0-5) and are therefore missing replicate-level detail.Stream invertebrates were surveyed at a series of sites on Macquarie Island, established in 1992 by Richard Marchant (Museums Victoria) under ASAC_555. At each site, five replicate kick samples were collected and taxon sorted and scored as presence/absence by R. Marchant. For 1992, these replicate-level data are available electronically (ASAC_555 metadata record .csv file), but for subsequent surveys in 2008, 2010 and 2016, the digitised data were entered as the sum of the five replicate samples for each site (values 0-5). These latter data were collected under ASAC_2918 (Nugegoda; 2008), AAS_3261 (Kefford; 2010) and AAS_4305 (Shaw; 2016). The data provided with this record are PDF file scans of the original hard copy, hand written, score sheets prepared by Richard Marchant as a record of replicate-level presence/absence data. Each sheet includes: <br/><br/> - Top Left corner = sample collection date (year and month/s)<br/> - Column 1 = taxa names (as provided in digitised records)<br/> - Header row 1 = site#replicate (e.g. 2#1, 2#2, 2#3, 2#4, 2#5 = site 2, replicates 1-5)<br/> - Presence = tick<br/> - Absence = empty cell<br/><br/>Other feint notes can be disregarded, these are additional notes made by R. Marchant during sample processing that relate to the general condition of the samples. <br/><br/>Data contact: Dr Richard Marchant, Senior Curator, Entomology, Museums Victoria Research Institute, Museums Victoria, GPO Box 666, Melbourne. VIC 3001, Australia | [email protected] | https://museumsvictoria.com.au/research-institute
Computer-assisted color separation instructional sequence for printing instructors
No full textTypescript (photocopy).The development and evaluation of the Marchant Color Separation System was the focus of this study. Color separation is the photographic process of producing four film transparencies from a color original in preparation for printing. The Marchant Color Separation System is a computer-assisted method of producing quality color separations using a microcomputer. It was expressly developed for use in educational institutions, which normally have limited resources for equipment and supplies. The goal of the system is to produce a set of color separation negatives that meet industry standards, has reasonable time requirements, and is affordable for the printing education community. The system takes the user step-by-step through the process of exposure tests, production exposures, and checks for quality. Exposure and development times are calculated by the system to produce masks and negatives which match accepted industry aim points. The system was tested in an in-service seminar for printing teachers and in a process camera photography course for university students. Hypotheses were established to test whether the teachers could produce an acceptable set of separation masks and negatives and if previous experience in teaching, industry, or the use of microcomputers would increase the achievement level. It was concluded that the system enabled teachers and university students to produce a color separation that met industry standards. The data did not support the hypothesis that previous experience would enable teachers to produce masks and separation negatives that more closely matched the listed aim points
Macquarie Island Stream Invertebrate surveys; site photos: 1992, 2008, 2010, 2016
No full textProgress Code: completed<b>Purpose</b><br/>Provide visual record of sites at each survey period.Macquarie Island stream invertebrate survey site photos, taken 1992, 2008, 2010 and 2016. Photos are arranged in subdirectory folders by site number. Year and site are included in photo filenames. <br/><br/>Sites 1-15 were established in 1992, as reported in Marchant and Lillywhite (1994); map (Figure 1) and grid reference (Appendix 2). See metadata record: ASAC_555 (https://data.aad.gov.au/metadata/ASAC_555). Additional sites (17-21) were added in 2008, with sites 1-17 reported in Marchant et al. (2011); map (Figure 1) and location data (Supplementary material; https://www.publish.csiro.au/mf/mf10317). Sites 18-21 are otherwise unreported. <br/><br/>Photos at the top level of each site folder are the most useful for site/vegetation assessment. Additional photos are provided in subfolders named "SiteXX-additional-photos"
Detection and characterisation of genetic associations with canine skull shape and disease
No full textThe brachycephalic head conformation is a morphological trait under human
selection across many popular breeds such as the Pug. The conformation is
characterised by the concurrent rostrocaudal shortening and mediolateral widening
of the skull. Overwhelming evidence suggests this skull conformation predisposes
breeds to a respiratory morbidity, Brachycephalic Obstructive Airway Syndrome
(BOAS) which restricts airflow. This is a major welfare concern.
To date, very little is known regarding the genetic factors underpinning canine
craniofacial variation or how such factors may influence BOAS aetiology. This project
utilised computer tomography scans of 560 dogs to generate high resolution three-dimensional
reconstructions of the skull. Geometric morphometric analysis
permitted the separation of the confounding influence of size on shape (allometry)
at an individual-level – a study design never previously utilised in dogs. Genome-wide
association studies (GWAS) using viscerocranial shape changes identified a QTL on
chromosome 1 associated with canine brachycephaly. Haplotype mapping refined
the critical interval to encompass the SPARC-related modular calcium-binding protein
2 (SMOC2) gene. Leveraging haplotype mapping and whole-genome sequencing, a
long interspersed nuclear element (LINE-1) was discovered within intron eight of
SMOC2. Transcriptomic analysis revealed the presence of alternative SMOC2
transcripts containing premature stop codons and a downregulation of the gene
among brachycephalic carriers of the LINE-1. Models of phenotypic effect predicted
that this structural variant explains up to 36% of the total craniofacial variation in the
dog.
Despite many brachycephalic dogs being fixed for the SMOC2 LINE-1 mutation,
heterogeneity in BOAS presentation suggests additional genetic factors contribute to
disease risk and presentation. To address this, a respiratory distress syndrome with
remarkable similarities to BOAS was assessed in the Norwich Terrier. Endoscopic
examinations of 233 Norwich Terriers graded and characterised the respiratory
syndrome for the use in a GWAS. A single QTL on chromosome 13 was associated
with changes in the structure of the laryngeal saccules and cartilage of affected dogs.
The underlying disease-associated haplotype encompassed the disintegrin and
metalloproteinase with thrombospondin motifs 3 (ADAMTS3) gene which was
observed to harbour a missense mutation in severely affected dogs. Screening for the
variant across 89 diverse dog breeds revealed it was enriched in brachycephalic
breeds, suggesting that the brachycephalic conformation alone does not completely
explain the presentation of BOAS in these breeds. Together, these results provide the
opportunity to improve animal welfare by offering genetic screening tests and further
our understanding of the condition which is driven by both skeletal and non-skeletal
factors
Embedding electronic growth charts into clinical practice at a children's hospital
No full textEmbedding electronic growth charts (EGCs) into clinical practice in a children's hospital. We employed initial implementation in the outpatient setting and subsequently extended this across inpatients with the growth chart following the child's records through both settings and significantly increasing growth data documentation.</p
Relationships between mental toughness and psychological wellbeing in undergraduate students
No full textThis study examined relationships between mental toughness (MT) and psychological wellbeing (PWB) in undergraduate students. Following previous research that identified significant and positive relations between MT and academic performance, it was hypothesised that MT would predict PWB within a student population. Participants were undergraduate students (n = 168) from nine United Kingdom universities. The sample included participants from a range of different degree programmes and from all three years of standard undergraduate study. Online questionnaires were completed to assess MT and PWB. Multiple linear regression analyses found that components of MT were moderate to strong predictors of PWB with between 35% and 64% of variance explained. Importantly, age, gender, and level of study were not found to predict PWB. These findings are consistent with stated hypotheses and further demonstrate the potential importance of MT within educational settings
Macquarie Island stream invertebrate survey 2016
No full textProgress Code: completed<b>Purpose</b><br/>Provide data for Macquarie Island stream invertebrate survey collected 2016.This data record is for stream invertebrate samples collected by Melissa Houghton from 13 site across Macquarie Island in December 2016. At each site, 5 biotic kick-samples and water quality measurements were collected and site photographs taken. Sites were originally established by Richard Marchant in 1992 (ASAC_555) and were resurveyed in 2008 and 2010 (ASAC_2918 & AAS_3261). Site numbers are as described for previous survey periods and for the 2016 survey included 1-11, 13 and 15. The biotic samples were returned to Australia for taxonomic sorting and identification by Richard Marchant. Site photographs were assessed by Jane Wasley for vegetation status (recovery from grazing) relative to matched photographs taken in previous years. <br/><br/>Some files attached to this record also include compiled data from previous surveys in 1992, 2008 and 2010. Three excel files are provided pertaining to: <br/><br/>1. Stream invertebrate taxa; 1992-2016<br/>2. Water quality; EC and turbidity for 2008 and 2016<br/>3. Vegetation; categorisation of change; grazing and recovery status 2008 and 2016<br/><br/>See parent and associated child records for further information
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