710 research outputs found
Dear Sir: I want a man by the Name of David Couper
No full textUnion Oregon, May 11, 1896.
Chief of Police.
Fort Worth, Texas.
Dear Sir: I want a man by the Name of David Couper, a Scotchman about thirty years or age, about six feet ono or two, black hair, usually wears a black mustache not very heavy, his hair may be a little tinged with grey, has rather prominent teeth, large eyes, has strong Scottish accent, is slim build, weighs about one fifty; or sixty. Ha is wanted for larceny by bailee. There was a letter left this morning addressed to your City in the name of David Campbell and I think it is Couper. If round wire me at once. Look closely, as I want him bad.
Yours very truly,
J. F. Phy Sheriff of Union County Oregon
South Australian experience with pediatric total pancreatectomy and islet autotransplantation for PRSS1-associated hereditary pancreatitis
No full textPerspectivesJessica Eldredge, Michael R Couper, David J Moore, Sanjeev Khurana, John WC Chen, Jennifer J Couper, Christopher J Drogemuller, Toni Radford, Thomas W Kay, Tom Loudovaris, Michael Wilks, Patrick T Coates, Richard TL Coupe
Supplementary_Figure_I_Study_Design - The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study
No full textSupplementary_Figure_I_Study_Design for The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study by Weihong Tang, Lu Yao, Ron C. Hoogeveen, Alvaro Alonso, David J. Couper, Pamela L. Lutsey, Carol C. Steenson, Weihua Guan, David W. Hunter, Frank A. Lederle, and Aaron R. Folsom in Angiology</p
Supplementary_Figure_II_and_Legend - The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study
No full textSupplementary_Figure_II_and_Legend for The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study by Weihong Tang, Lu Yao, Ron C. Hoogeveen, Alvaro Alonso, David J. Couper, Pamela L. Lutsey, Carol C. Steenson, Weihua Guan, David W. Hunter, Frank A. Lederle, and Aaron R. Folsom in Angiology</p
Supplementary_Tables_v5_2clean - The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study
No full textSupplementary_Tables_v5_2clean for The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study by Weihong Tang, Lu Yao, Ron C. Hoogeveen, Alvaro Alonso, David J. Couper, Pamela L. Lutsey, Carol C. Steenson, Weihua Guan, David W. Hunter, Frank A. Lederle, and Aaron R. Folsom in Angiology</p
University Chorale, April 7, 1998, 04/07
No full textRecorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, April 7, 1998, 8:00 p.m., the 501st concert of the School of Music's 1997-1998 season.Western Michigan University Chorale, Craig S. Arnold, conductor ; David Close, accompanist ; assisted by the Western String Chamber Orchestra, Bruce J. Uchimura, conductor (in the 9th work) ; various vocal soloists and instrumentalists.Sacred and secular vocal music for mixed chorus, in part with instrumental accompaniment.Information from performance program.Wake, awake, for night is flying / Philipp Nicolai ; arranged by F. Melius Christiansen -- Psalm no. 8 : for a cappella choir / Ramon Zupko -- ""Ave Maria"" from Triptych / Alan Hovhaness (women of the chorale ; Chris Sargent, synthesizer) -- Inveni David / Anton Bruckner (men of the chorale ; Matt Westgate, David Krosschell, Chris Sargent, Ibrahim Sodawalla, trombones) -- Quand je fus pris au pavillon / Reynaldo Hahn (Diana B. Nordlund, mezzo-soprano ; David Close, piano) -- ""In quelle trine morbide"" from Manon Lescaut / Giacomo Puccini (Renée Carriere, soprano ; Gunta Laukmane, piano) -- Etude in F minor, op. 25, no. 2 / Frédéric Chopin (Carrie Bursch, piano) -- ""Every valley"" from Messiah / George Frideric Handel (John Russell, tenor ; Sean Mirate, piano) -- Trio from Act III of Der Rosenkavalier / Richard Strauss (Amanda Wells (Marschallin), Michelle LaGruth (Octavian), Amy Schaub (Sophie) ; Gunta Laukmane, piano) -- Grand mass in C minor, K. 427. Kyrie (Carrie Sikkenga, mezzo-soprano) ; Gloria ; Credo ; Sanctus / Wolfgang Amadeus Mozart -- Ave Maria / Javier Busto -- Black sheep / American lullaby ; arranged by John Rutter (Ellen Wingertzahn, soprano) -- Quicksand years / René Clausen (Scott Couper, baritone) -- Tonight, eternity alone / René Clausen (Karen Huber, Carrie Bursch, sopranos)
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Australian experience with total pancreatectomy with islet autotransplantation to treat chronic pancreatitis
No full textFirst published: 06 May 2021BACKGROUND: This study aimed to describe the clinical outcomes of total pancreatectomy with islet autotransplantation (TP-IAT) in Australia. METHODS: Individuals selected for TP-IAT surgery according to the Minnesota Criteria (Appendix) without evidence of diabetes were evaluated including time to transplantation from pancreatectomy, islet numbers infused and post-transplantation HbA1c, C-peptide, total daily insulin and analgesic requirement. RESULTS: Sixteen individuals underwent TP-IAT from Australia and New Zealand between 2010 and 2020. Two recipients are deceased. The median islet equivalents/kg infused was 4244 (interquartile range (IQR) 2290-7300). The median C-peptide 1 month post-TP-IAT was 384 (IQR 210-579) pmol/L and at median 29.5 (IQR 14.5-46.5) months from transplant was 395 (IQR 139-862) pmol/L. Insulin independence was achieved in eight of 15 (53.3%) surviving recipients. A higher islet equivalents transplanted was most strongly associated with the likelihood of insulin independence (P < 0.05). Of the 15 surviving recipients, 14 demonstrated substantial reduction in analgesic requirement. CONCLUSION: The TP-IAT programme in Australia has been a successful new therapy for the management of individuals with chronic pancreatitis including hereditary forms refractory to medical treatment to improve pain management with 50% insulin independence rates.Tristan J. Bampton, D. Jane Holmes-Walker, Chris J. Drogemuller, Toni Radford, Patricia Anderson, C. Etherton, C. H. Russell, S. Khurana, David J. Torpy, J. J. Couper, R. L. T. Couper, Pamela Macintyre, E. L. Neo, Paul Benitez-Aguirre, G. Thomas, T. Loudovaris, H. E. Thomas, Lyle J. Palmer, Denghao Wu, Natasha M. Rogers, L. Williams, W. J. Hawthorne, P. J. O, Connell, Tom W. Kay, Henry Pleass, John W. Chen, and P. Toby Coates, Australian Islet Consortiu
Hepatocyte growth factor and macrophage-stimulating protein are upregulated during excisional wound repair in rats
No full textThe original publication is available at www.springerlink.comHepatocyte growth factor (HGF) and macrophage-stimulating protein (MSP) are structurally related molecules that stimulate epithelial cell proliferation and migration. MSP also acts directly as a chemoattractant for resident macrophages. These activities are integral to the wound repair processes of inflammation, epithelialization and tissue remodelling. To begin to examine the involvement of HGF and MSP in healing of cutaneous wounds we have mapped the temporal expression of these two molecules and their receptors, MET and RON respectively, in adult rat excisional wounds. Four 222-cm full-thickness excisional wounds were created on the dorsum of 18 rats, and biopsies were taken through the wounds at 3, 5, 7, 14, 21, and 28 days postwounding. These biopsies were analyzed using immunofluorescent staining and in situ hybridization (ISH). The number of cells staining positively for HGF and MET significantly increased in response to wounding. HGF staining and mRNA peaked at 7 days postwounding whereas MET was upregulated earlier, peaking after 3 days. Both HGF and MET protein were observed in fibroblasts of the dermis and in the newly forming granulation tissue. ISH studies also revealed that fibroblasts at the wound edges and within the newly forming granulation tissue also expressed HGF and c-met mRNA. Immunofluorescent staining revealed both MSP and RON within the wound, with maximum staining occurring between 7 and 21 days for both the ligand and receptor. In addition, MSP co-localized with a small subset of ED1-positive cells (monocytes). In contrast, ED2-positive cells (macrophages) did not co-localize with MSP. Thus, increased expression of HGF, MSP and their receptors MET and RON respectively was observed in response to wounding. Furthermore, MSP co-localization with a subset of monocytes may confirm a role for MSP in the activation of mature macrophages, which may be important in tissue remodelling.Allison J. Cowin, Nick Kallincos, Nick Hatzirodos, Gray J. Robertson, Kaylene J. Pickering, Jenny Couper, David A. Belfor
First Australian report of vitamin D-dependent rickets type I
No full textNobuaki Ito, Alexia S Peña, Shiree Perano, Gerald J Atkins, David M Findlay, Jennifer J Coupe
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