850,692 research outputs found
David J. Hoss Vietnam War collection
No full textThis collection contains an oral history interview with David J. Hoss Jr. from March 2015, as well as, documents and photographs related to his military service
David J. Herzig, 2003 October
No full textInterview with David J. Herzig conducted by Enid Galler.http://deepblue.lib.umich.edu/bitstream/2027.42/134310/2/0001.ziphttp://deepblue.lib.umich.edu/bitstream/2027.42/134310/3/herzig.zi
No.305, David J. Miller, interview by Tim Larson
No full textTranscript (77 pages) of interview by Tim Larson with David J. Miller, formerly an employee of radio stations in Utah, on September 25, 1989. This interview is no. 305 in the Everett L. Cooley Oral History Project, and tape nos. U-1092 and U-1093In two interviews David J. Miller (b. 1950) recalls growing up in Utah, attending Utah State University, becoming involved in radio broadcasting in Logan, Utah, later in St. George, Utah and at the time of the interview in Oregon with Frank Carman who had been a pioneer in Utah radio broadcasting. Interviewer: Tim Larso
David J. Clark
No full text"SX 27370 L/Cp. David J. Clark N.T. Force Sigs/12 Div Sigs. Coomalie Creek "A" [Sect]".SX 27370 Lance Corporal David J. Clark. Northern Territory Force Signals/12 Division Signals. Coomalie Creek. "A" [Section]
Interview with David J. Berg
No full textClarke A. Chambers interviews David J. Berg, a member of Central Administration.Berg, David J.; Chambers, Clarke A.. (1994). Interview with David J. Berg. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/48989
Evolution of cooperation among tumor cells
No full textThe evolution of cooperation has a well established theoretical framework based on game theory. This approach has made valuable contributions to a wide variety of disciplines, including political science, economics, and evolutionary biology. Existing cancer theory suggests that individual clones of cancer cells evolve independently from one another, acquiring all of the genetic traits or hallmarks necessary to form a malignant tumor. It is also now recognized that tumors are heterotypic, with cancer cells interacting with normal stromal cells within the issue microenvironment, including endothelial, stromal, and nerve cells. This tumor cell???stromal cell interaction in itself is a form of commensalism, because it has been demonstrated that these nonmalignant cells support and even enable tumor growth. Here, we add to this theory by regarding tumor cells as game players whose interactions help to determine their Darwinian fitness. We marshal evidence that tumor cells overcome certain host defenses by means of diffusible products. Our original contribution is to raise the possibility that two nearby cells can protect each other from a set of host defenses that neither could survive alone. Cooperation can evolve as byproduct mutualism among genetically diverse tumor cells. Our hypothesis supplements, but does not supplant, the traditional view of carcinogenesis in which one clonal population of cells develops all of the necessary genetic traits independently to form a tumor. Cooperation through the sharing of diffusible products raises new questions about tumorigenesis and has implications for understanding observed phenomena, designing new experiments, and developing new therapeutic approaches.Author manuscript. Published in final edited form as: Proc Natl Acad Sci U S A. 2006 September 5; 103(36): 13474-13479.The final published version of this article is located at: www.pnas.org/cgi/doi/10.1073/pnas.0606053103NIH U56 CA113004; to David E. AxelrodR.A. was supported by National Science Foundation (NSF) Grant SES-0240852. D.E.A. was supported by NSF Grant IIS-0312953, National Institutes of Health (NIH) Grant U56 CA113004, and New Jersey Commission on Cancer Research Grant 1076-CCR-SO. K.J.P. is an American Cancer Society Clinical Research Professor and is supported by NIH Grants CA69568, CA102872, and CA093900.NIH CA69568; to Kenneth J. PientaNIH CA102872; to Kenneth J. PientaNIH CA093900; to Kenneth J. PientaNSF SES-0240852; to Robert AxelrodNJ Commission on Cancer Research 1076-CCR-SO; to David E. AxelrodAlso available in PubMed Central. PMCID: PMC155738
Correspondence of David Lawrence McKay, January 1935 to May 1936
No full textScans of letters sent to David Lawrence McKay during the period from January 1935 to May 1936. Most of the letters are from one or both of his parents, David O. and Emma Ray McKay. Also a letter from "Ned," David\u27s younger brother Edward; and a letter from Emma Ray to granddaughter Midene
The David W. Fentress Family Letters, 1856-1969
No full textLetter from David Fentress to his wife Clara telling her that Mr. J. H. Hodges would be returning home to collect clothing for his company. He gives updates on the war; his health; and the health of his fellow soldiers
Correspondence of David Lawrence McKay, September 1929 to June 1934
No full textScans of letters sent to David Lawrence McKay during the period from September 1929 to June 1934. All of the letters are from his parents, David O. and Emma Ray McKay, and some are also addressed to Mildred, David Lawrence\u27s wife
Correspondence of David Lawrence McKay, December 1922 to March 1923
No full textCopies of letters sent to or from David Lawrence McKay during the period from December of 1922 to March of 1923, while he was serving in the Swiss and German Mission for the Church of Jesus Christ of Latter-day Saints. The letters are from his parents (David O. and Emma Ray McKay); his sister, Louise Jeanette McKay; his brother, Llewelyn Riggs McKay; and his uncle, Thomas Evans McKay. Also two notes dated 17 February 1923 from his sisters, Emma Ray and Edward ("Ned") to their parents (David O. and Emma Ray McKay)
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