19,505 research outputs found
sj-docx-1-han-10.1177_15589447241233709 – Supplemental material for Understanding Variations in the Management of Displaced Distal Radius Fractures With Satisfactory Reduction
No full textSupplemental material, sj-docx-1-han-10.1177_15589447241233709 for Understanding Variations in the Management of Displaced Distal Radius Fractures With Satisfactory Reduction by Jomar N. A. Aryee, Giulia C. Frias, Daniel K. Haddad, Kevin D. Guerrero, Vivian Chen, Fan Ling, David A. Kirschenbaum, James T. Monica and Brian M. Katt in HAND</p
sj-docx-1-han-10.1177_15589447231221170 – Supplemental material for Brachial Gunshot Wounds: Injury Patterns and Considerations for Managing the Abnormal Neurological Examination
No full textSupplemental material, sj-docx-1-han-10.1177_15589447231221170 for Brachial Gunshot Wounds: Injury Patterns and Considerations for Managing the Abnormal Neurological Examination by David Chi, Damini Tandon, Adam G. Evans, Danielle J. Brown, Rachael M. Payne, Amelia C. Van Handel, Kevin G. Shim, Susan E. Mackinnon and Mitchell A. Pet in HAND</p
Designing bidding strategies in sequential auctions for risk averse agents
No full textDesigning efficient bidding strategies for sequential auctions represents an important, open problem area in agent-mediated electronic markets. In existing literature, a variety of bidding strategies have been proposed and have been shown to perform with varying degrees of efficiency. However, most of strategies proposed so far do not explicitly model bidders attitudes towards risk which, in mainstream economic literature, is considered an essential attribute in modeling agent preferences and decision making under uncertainty. This paper studies the effect that risk profiles (modeled through the standard Arrow-Pratt risk aversion measure), have on the bidders strategies in sequential auctions. First, the sequential decision process involved in bidding is modeled as a Markov Decision Process. Then, the effect that a bidders risk aversion has on her decision theoretic optimal bidding policy is analyzed, for a category of expectations of future price distributions. This analysis is performed separately for the case of first price and second-price sequential auctions. Next, the bidding strategies developed above are simulated, in order to study the effect that an agents risk aversion has on the chances of winning a set of complementary-valued items. The paper concludes with an experimental study of how the presence of risk-averse bidders affects both bidder profits and auctioneer revenue, for different market scenarios of increasing complexity
Dataset for Electrodeposition of GeSbTe Based Resistive Switching Memory in Crossbar Arrays
No full textThis dataset is for the paper titled “Electrodeposition of GeSbTe Based Resistive Switching Memory in Crossbar Arrays” with authors Jaafar, Ayoub; Meng, Lingcong; Noori, Yasir; Zhang, Wenjian; Han, Yisong; Beanland, Richard; Smith, David; Reid, Gillian; de Groot, C.H. (Kees); Huang, Ruomeng; Bartlett, Philip to the Journal of Physical Chemistry C. (Manuscript ID: jp-2021-08549r)</span
Well-measuring programs
No full text© Copyright 2006 IEEEAny program that measures quantities from its physical environment must compute using correct and consistent units of measurement. Such a program is described as well-measuring. In many systems, particularly embedded control software, paying inadequate attention to units of measurement can result in catastrophe. Unfortunately, current programming languages and tools provide little aid to the programmer attempting to establish or verify the well-measuring property. We present a program analysis technique for inferring and checking the units used within a program. The technique combines traditional Hindley-Milner-style type inference with the use of static single assignment (SSA) form to enable analysis of imperative programs.Phil Cook, Colin Fidge, and David Heme
Also By The Same Author: AKTiveAuthor, a Citation Graph Approach to Name Disambiguation
No full textThe desire for definitive data and the semantic web drive for inference over heterogeneous data sources requires co-reference resolution to be performed on those data. In particular, name disambiguation is required to allow accurate publication lists, citation counts and impact measures to be determined. This paper describes a graph-based approach to author disambiguation on large-scale citation networks. Using self-citation, co-authorship and document source analyses, AKTiveAuthor clusters papers, achieving precision of 0.997 and recall of 0.818 over a test group of eight surname clusters
A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers
No full textBackground and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV infection in Asian populations. Most significant associations were observed for the A alleles of HLA-DPA1 rs3077 and HLA-DPB1 rs9277535, which conferred a decreased risk for HBV infection. We assessed the implications of these variants for HBV infection in Caucasians.
Methods: Two HLA-DP gene variants (rs3077 and rs9277535) were analyzed for associations with persistent HBV infection and with different clinical outcomes, i.e., inactive HBsAg carrier status versus progressive chronic HBV (CHB) infection in Caucasian patients (n = 201) and HBsAg negative controls (n = 235).
Results: The HLA-DPA1 rs3077 C allele was significantly associated with HBV infection (odds ratio, OR = 5.1, 95% confidence interval, CI: 1.9–13.7; p = 0.00093). However, no significant association was seen for rs3077 with progressive CHB infection versus inactive HBsAg carrier status (OR = 2.7, 95% CI: 0.6–11.1; p = 0.31). In contrast, HLA-DPB1 rs9277535 was not associated with HBV infection in Caucasians (OR = 0.8, 95% CI: 0.4–1.9; p = 1).
Conclusions: A highly significant association of HLA-DPA1 rs3077 with HBV infection was observed in Caucasians. However, as a differentiation between different clinical courses of HBV infection was not possible, knowledge of the HLA-DPA1 genotype cannot be translated into personalized anti-HBV therapy approaches
Estimating energy savings from benchmarking policies in New York City
No full textA growing number of governments have begun to implement benchmarking or energy disclosure policies. By requiring owners to measure and disclose their energy use, these policies are intended to transform the market for energy-efficient investments in existing buildings. To improve future policy efforts, two critical questions are: first, how much energy do these policies save? and second, what particular aspects of these policies are most effective? To answer these questions, this study explores how different aspects of these policies were phased-in to different groups of buildings over the first four years of the City of New York's benchmarking ordinance. By applying a novel difference-in-differences strategy, we can causally attribute observed declines in energy consumption to specific owner behaviors and policy mechanisms. Our analysis indicates that in comparison with the control group and before the policies were implemented in 2011, total disclosure of both energy use and Energy Star together can be credited with a 6% reduction in building energy use intensity (EUI) three years later and a 14% reduction in EUI four years later. Disclosure of Energy Star scores decreased building EUI by 9% three years later and 13% four years later. These two separate findings are a consequence of the policy design and different control groups. (C) 2017 Elsevier Ltd. All rights reserved.
Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling
No full textThe Tcf/Lef family of transcription factors mediates the Wnt/��-catenin pathway that is involved in a wide range of biological processes, including vertebrate embryogenesis and diverse pathogenesis. Post-translational modifications, including phosphorylation, sumoylation and acetylation, are known to be important for the regulation of Tcf/Lef proteins. However, the importance of ubiquitination and ubiquitin-mediated regulatory mechanisms for Tcf/Lef activity are still unclear. Here, we newly show that ubiquitin C-terminal hydrolase 37 (Uch37), a deubiquitinase, interacts with Tcf7 (formerly named Tcf1) to activate Wnt signalling. Biochemical analyses demonstrated that deubiquitinating activity of Uch37 is not involved in Tcf7 protein stability but is required for the association of Tcf7 to target gene promoter in both Xenopus embryo and human liver cancer cells. In vivo analyses further revealed that Uch37 functions as a positive regulator of the Wnt/��-catenin pathway downstream of ��-catenin stabilization that is required for the expression of ventrolateral mesoderm genes during Xenopus gastrulation. Our study provides a new mechanism for chromatin occupancy of Tcf7 and uncovers the physiological significance of Uch37 during early vertebrate development by regulating the Wnt/��-catenin pathway. ? 2017 The Author(s).113Ysciescopu
Designing Risk-Averse Bidding Strategies in Sequential Auctions for Transportation Orders
No full textDesigning efficient bidding strategies for agents participating in multiple, sequential auctions remains an important challenge for researchers in agent-mediated electronic markets. The problem is particularly hard if the bidding agents have complementary (i.e. super-additive) utilities for the items being auctioned, such as is often the case in distributed transportation logistics. This paper studies the effect that a bidding agent’s attitude towards taking risks plays in her optimal, decision-theoretic bidding strategy. We model the sequential bidding decision process as an MDP and we analyze, for a category of expectations of future price distributions, the effect that a bidder’s risk aversion profile has on her decision-theoretic optimal bidding policy. Next, we simulate the above strategies, and we study the effect that an agent’s risk aversion has on the chances of winning the desired items, as well as on the market efficiency and expected seller revenue. The paper extends the results presented in our previous work (reported in [1]), not only by providing additional details regarding the analytical part, but also by considering a more complex and realistic market setting for the simulations. This simulation setting is based on a real transportation logistics scenario [2]), in which bidders have to choose between several combinations (bundles) of orders that can be contracted for transportation
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