66,839 research outputs found

    Snacks 31 -- David Warlick!

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    Includes descriptive metadata provided by producer in MP3 file: "Snacks 4 the Brain! - Podcasts - Snacks 31 -- David Warlick!" Scott Merrick interviews David Warlick, a North Carolina educator, educational technology specialist, programmer and author. Podcasting in education, and in particular Warlicks' "Connect Learning" podcast series, are among the topics of discussion, as are science education and the implications of young people's use of MySpace.Vanderbilt University. Medical Cente

    White matter damage and cognitive impairment after traumatic brain injury

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    White matter disruption is an important determinant of cognitive impairment after brain injury, but conventional neuroimaging underestimates its extent. In contrast, diffusion tensor imaging provides a validated and sensitive way of identifying the impact of axonal injury. The relationship between cognitive impairment after traumatic brain injury and white matter damage is likely to be complex. We applied a flexible technique—tract-based spatial statistics—to explore whether damage to specific white matter tracts is associated with particular patterns of cognitive impairment. The commonly affected domains of memory, executive function and information processing speed were investigated in 28 patients in the post-acute / chronic phase following traumatic brain injury and in 26 age-matched controls. Analysis of fractional anisotropy and diffusivity maps revealed widespread differences in white matter integrity between the groups. Patients showed large areas of reduced fractional anisotropy, as well as increased mean and axial diffusivities, compared with controls, despite the small amounts of cortical and white matter damage visible on standard imaging. A stratified analysis based on the presence or absence of microbleeds (a marker of diffuse axonal injury) revealed diffusion tensor imaging to be more sensitive than gradient-echo imaging to white matter damage. The location of white matter abnormality predicted cognitive function to some extent. The structure of the fornices was correlated with associative learning and memory across both patient and control groups, whilst the structure of frontal lobe connections showed relationships with executive function that differed in the two groups. These results highlight the complexity of the relationships between white matter structure and cognition. Although widespread and, sometimes, chronic abnormalities of white matter are identifiable following traumatic brain injury, the impact of these changes on cognitive function is likely to depend on damage to key pathways that link nodes in the distributed brain networks supporting high-level cognitive functions

    Snacks 59--David Warlick at "Web 2.0 and Us"

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    Includes descriptive metadata provided by producer in MP3 file: "Snacks 4 the Brain! - Podcasts - Snacks 59--David Warlick at 'Web 2.0 and Us'." This episode features a chat Merrick facilitated in July 2007, between participants of a workshop Merrick offered for teachers at his school (University School of Nashville) and educational change advocate David Warlick. David blogs an immensely popular site called 2 cents worth and hosts an educational podcast called connect-learning. The workshop participants used a blog and a wiki to archive their learning about the use of Web 2.0 technologies in the service of education.Vanderbilt University. Medical Cente

    Eight Questions about Brain Drain

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    High-skilled emigration is an emotive issue that in popular discourse is often referred to as brain drain, conjuring images of extremely negative impacts on developing countries. Recent discussions of brain gain, diaspora effects, and other advantages of migration have been used to argue against this, but much of the discussion has been absent of evidence. This paper builds upon a new wave of empirical research to answer eight key questions underlying much of the brain drain debate: 1) What is brain drain? 2) Why should economists care about it? 3) Is brain drain increasing? 4) Is there a positive relationship between skilled and unskilled migration? 5) What makes brain drain more likely? 6) Does brain gain exist? 7) Do high-skilled workers remit, invest, and share knowledge back home? and 8) What do we know about the fiscal and production externalities of brain drain?Brain drain, Brain gain, High-skilled Emigration, Development

    Eight Questions about Brain Drain

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    High-skilled emigration is an emotive issue that in popular discourse is often referred to as brain drain, conjuring images of extremely negative impacts on developing countries. Recent discussions of brain gain, diaspora effects, and other advantages of migration have been used to argue against this, but much of the discussion has been absent of evidence. This paper builds upon a new wave of empirical research to answer eight key questions underlying much of the brain drain debate: 1) What is brain drain? 2) Why should economists care about it? 3) Is brain drain increasing? 4) Is there a positive relationship between skilled and unskilled migration? 5) What makes brain drain more likely? 6) Does brain gain exist? 7) Do high-skilled workers remit, invest, and share knowledge back home? and 8) What do we know about the fiscal and production externalities of brain drain?high-skilled emigration, brain gain, brain drain, development

    Eight questions about brain drain

    No full text
    High-skilled emigration is an emotive issue that in popular discourse is often referred to as brain drain, conjuring images of extremely negative impacts on developing countries. Recent discussions of brain gain, diaspora effects, and other advantages of migration have been used to argue against this, but much of the discussion has been absent of evidence. This paper builds upon a new wave of empirical research to answer eight key questions underlying much of the brain drain debate: 1) What is brain drain? 2) Why should economists care about it? 3) Is brain drain increasing? 4) Is there a positive relationship between skilled and unskilled migration? 5) What makes brain drain more likely? 6) Does brain gain exist? 7) Do high-skilled workers remit, invest, and share knowledge back home? and 8) What do we know about the fiscal and production externalities of brain drain?Population Policies,Tertiary Education,International Migration,Health Monitoring&Evaluation,Remittances

    Lateral Fluid Percussion: Model of Traumatic Brain Injury in Mice

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    Traumatic brain injury (TBI) research has attained renewed momentum due to the increasing awareness of head injuries, which result in morbidity and mortality. Based on the nature of primary injury following TBI, complex and heterogeneous secondary consequences result, which are followed by regenerative processes 1,2. Primary injury can be induced by a direct contusion to the brain from skull fracture or from shearing and stretching of tissue causing displacement of brain due to movement 3,4. The resulting hematomas and lacerations cause a vascular response 3,5, and the morphological and functional damage of the white matter leads to diffuse axonal injury 6- 8. Additional secondary changes commonly seen in the brain are edema and increased intracranial pressure 9. Following TBI there are microscopic alterations in biochemical and physiological pathways involving the release of excitotoxic neurotransmitters, immune mediators and oxygen radicals 10-12, which ultimately result in long-term neurological disabilities 13,14. Thus choosing appropriate animal models of TBI that present similar cellular and molecular events in human and rodent TBI is critical for studying the mechanisms underlying injury and repair. Various experimental models of TBI have been developed to reproduce aspects of TBI observed in humans, among them three specific models are widely adapted for rodents: fluid percussion, cortical impact and weight drop/impact acceleration 1. The fluid percussion device produces an injury through a craniectomy by applying a brief fluid pressure pulse on to the intact dura. The pulse is created by a pendulum striking the piston of a reservoir of fluid. The percussion produces brief displacement and deformation of neural tissue 1,15. Conversely, cortical impact injury delivers mechanical energy to the intact dura via a rigid impactor under pneumatic pressure 16,17. The weight drop/impact model is characterized by the fall of a rod with a specific mass on the closed skull 18. Among the TBI models, LFP is the most established and commonly used model to evaluate mixed focal and diffuse brain injury 19. It is reproducible and is standardized to allow for the manipulation of injury parameters. LFP recapitulates injuries observed in humans, thus rendering it clinically relevant, and allows for exploration of novel therapeutics for clinical translation 20. We describe the detailed protocol to perform LFP procedure in mice. The injury inflicted is mild to moderate, with brain regions such as cortex, hippocampus and corpus callosum being most vulnerable. Hippocampal and motor learning tasks are explored following LFP.Peer reviewe

    An Interview with Tony David Sampson: Author of Virality: Contagion Theory in the Age of Networks

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    Tony D. Sampson is Reader in Digital Culture and Communication in the School of Arts and Digital Industries (ADI) at the University of East London, where he directs the EmotionUX lab, supervising research on the cognitive, emotional, and affective aspects of user experience. In 2013, he co-founded Club Critical Theory, an organization dedicated to the application of critical theory in everyday life in Southend-on-Sea, Essex. Tony is the author of Virality: Contagion Theory in the Age of Networks and The Assemblage Brain: Sense Making in Neuroculture, both from the University of Minnesota Press. He blogs at viralcontagion.wordpress.com. The editors of this special NANO issue are delighted to have the opportunity to talk with Tony about how his work touches on issues of imitation and contagion—a loaded term unpacked within his 2012 book

    EEG KISS: Shared Multi-modal, Multi Brain Computer Interface Experience, in Public Space

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    Can shared intimate experience of social touch be mediated through multi-brain-computer interface (Multi-brain BCI) interaction in public space? Two artistic EEG KISS orchestrations, both multi-modal, multi-brain BCIs, are shown to create novel shared experiences of social touch in public space. These orchestrations purposefully disrupt and translate known forms of face-to-face connection and sound, to re-orchestrate unfamiliar sensory syntheses of seeing, hearing, touching and moving, connected to data-visualization and audification of brain activity. The familiar sensory relations between ‘who you kiss and who is being kissed, what you see and what you hear’ are captured in a model of digital synaesthetics in multi-modal multi brain BCI interaction for social touch. This model links hosted self-disclosure, witnessing, dialogue and reflection to intimate experience in public space through syntheses of the senses. As such, this model facilitates the design of new shared intimate experiences of multi modal multi brain BCI interaction through social touch in public space.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.System Engineerin

    Snacks 39--David Salisbury and "Exploration!"

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    Includes descriptive metadata provided by producer in MP3 file: "Snacks 4 the Brain! - Podcasts - Snacks 39 -- David Salisbury and 'Exploration!'" Scott Merrick talks to David Salisbury, Assistant Director of Science and Research Communications at Vanderbilt University, on various subjects, including the Vanderbilt science communication Web site called Exploration. Merrick also reads a Tennessean newspaper article by Todd Pack, on a possible physician shortage in the U.S. in the near future and how Tennessee medical schools are reacting to it. A "tech tidbit" about when printers should be turned off, and why, is offered. Finally, three songs from the Podsafe Music Network and GarageBand.com, by Aerosol Halo, Happy Rhodes, and Joe Turley, are included.Vanderbilt University. Medical Cente
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