1,605 research outputs found
Tim Reardon's Remarks at the College of Business Administration Dedication, 1984
No full textRemarks by Business Administration Student Council President Tim Reardon at the College of Business Administration Dedication as David A. Straz, Jr. Hall, December 2, 1984
CH-CH-CH-CHANGES: ARTISTS TALK ABOUT TEACHING
No full textAn indispensable guide for artists, teachers and students, this volume of interviews focuses on artists teaching Europe, predominantly in the UK and Germany. The interviews provide an insight into the artist’s different teaching methods and the impact their role as teachers has on their work – bringing to light their often heroic endeavors to survive within the world of art education. Selected from a variety of institutions including Goldsmiths, London; Glasgow School of Art; Staatliche Hochschule für Bildende Künste, Frankfurt and the Kunstakademie Münster, it represents a range of approaches to teaching. Artists interviewed include: Phyllida Barlow, Thomas Bayrle, Pavel Bücher, Michael Craig-Martin, Graham Crowley, Liam Gillick, John Hillard, Klaus Jung, Simon Lewandowski, Philip Napier, Tobias Rehberger, Christoph Schlingensief, John Thompson, Richard Wentworth and more
Glioblastoma
No full textGlioblastoma is the most common primary parenchymal brain tumor. Its histopathological definition is based essentially on the presence of tumor cells thought to be of neuroglial origin and on the detection of neovascularization and necrosis. At the molecular level, glioblastomas are typically characterized by the absence of isocitrate dehydrogenase (IDH) 1 or 2 mutations and the presence of mutations in genes regulating receptor tyrosine kinase (RTK)/rat sarcoma (RAS)/phosphoinositide 3-kinase (PI3K), p53, and retinoblastoma protein (RB) signaling. Amplifications and mutations of the epidermal growth factor receptor (EGFR) gene are found in 40% of the tumors. Giant cell glioblastoma, gliosarcoma, and epithelioid glioblastoma are morphological variants with a similar molecular profile. Gain of function mutations of the IDH 1 or 2 genes define a subgroup of patients with glioblastomas that occur at younger age and share a more favorable outcome. Histone mutations, mostly H3K27M, have been described in a subset of midline and thalamic gliomas characterized by poor prognosis. The standard of care for typical IDH wild-type glioblastoma comprises maximum safe resection as feasible followed by involved field radiotherapy with concomitant and then six cycles of maintenance temozolomide chemotherapy. Methylation of the promoter region of the DNA repair gene, O6-methylguanyl DNA methyltransferase (MGMT), predicts prolonged progression-free and overall survival for patients treated with alkylating agent chemotherapy. Testing for MGMT promoter methylation plays a particular role for selecting between radiotherapy alone and temozolomide alone for patients not considered to be eligible for combined modality treatment. Interventions at progression are more individualized, pharmacotherapy with lomustine and bevacizumab, depending on availability, being most frequently used, although survival gains with these approaches are probably small. Tumor-treating fields are a novel treatment approach based on the exposure of the affected brain region to an alternating low-voltage electrical field which has been shown to prolong survival in an open-label randomized trial in the newly diagnosed setting, but not in recurrent disease. Current topics of controversy concern the integration of tumor-treating fields into standards of care and the future role of targeted therapy and immunotherapy approaches including vaccination
The case of Mobility as a Service: A critical reflection on challenges for urban transport and mobility governance
No full textThis chapter provides a reflective critique of Mobility as a Service (MaaS), an emerging development seeking a role within the Smart Mobility paradigm. We assess a range of its future implications for urban policymakers in terms of governance and sustainability (i.e., social and environmental impacts). We begin by describing the origins of the MaaS concept, along with the features of precursor technologies and current early examples. We then reflect on the marketing of MaaS and use it to consider how we might anticipate some potentially less desirable aspects of the promoted business models. Finally, we discuss the implications for governance.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Spatial Planning and StrategyTransport and Plannin
Springfield Diving Fundamentals (1978)
No full textThis booklet titled "Springfield Diving Fundamentals" was written by Charles J. Smith (Springfield College's diving coach) and Edward V. Reardon (a previous varsity diver for Springfield who graduated in 1976). The book was written to assist both coaches and divers during the learning process of diving. It is filled with photographs and analyses of the different types of dives. It was dedicated to Edward V. Reardon and James "Butch" Podmore. and is dated December 20, 1978. The book begins with an introduction to diving and the principles and conditioning techniques associated with the sport. Multiple dives are then looked at, including: forward dives, back dives, reverse dives, inward dives, forward dive with twists, and dives with somersaults. Each dive is described with instructions and a picture for more clarification. Two Springfield College divers are used in the booklet, including Bruce Mitchell, Class of 1974, Joseph Gallagher, Class of 1976, David Siconolfi, Class of 1973, and Alice Barber, Class of 1979. The book has a signed message to Dr. Edward Stietz in the front cover.Charles J. Smith graduated from Springfield College in 1955, and became a member of the physical education faculty in 1966. At this time, he became the head diving coach and assistant varsity coach, until becoming the head coach in 1978. Edward V. Reardon received his bachelors from Springfield. During his four years of swimming, he earned All-New England honors in 1975 and 1976. He was the 1978 New England AAU Senior Men's one meter champion
A year into the pandemic:shifts, improvisations and impacts for people, place, and policy
No full textThis chapter provides an overarching framework for exploring the relationships between people, place and policy and living with the COVID-19 pandemic. It recognises that these three Ps are interdependent; people are embedded in places and local and national policy is developed and applied to places. The chapter starts by exploring the debate on risk societies, non-calculable uncertainty, and the emergence of Jenga capitalism as a precursor for exploring the impacts of Covid-19. It then explores the relationship between globalisation and disease, before outlining national responses to COVID-19, including the emergence of socially distanced economies. The chapter also considers some dimensions of life after the pandemic, including a discussion of the impacts on policy and taxation. In so doing, the Chapter highlights Covid-19 as a cultural inflection point. The Chapter concludes by providing an outline of the contributions to the edited collection of the same name, to which this chapter forms the introduction
The Digital Role-Playing Game and Technical Communication: A History of Bethesda, BioWare, and CD Projekt Red
No full textWith annual gross sales surpassing 100 billion U.S. dollars each of the last two years, the digital games industry may one day challenge theatrical-release movies as the highest-grossing entertainment media in the world. In their examination of the tremendous cultural influence of digital games, Daniel Reardon and David Wright analyze three companies that have shaped the industry: Bethesda, located in Rockville, Maryland; BioWare in Edmonton, Alberta, and CD Projekt Red in Warsaw, Poland.
Each company has used social media and technical content in the games to promote players\u27 belief that players control the companies\u27 game narratives. The result has been at times explosive, as empowered players often attempted to co-op the creative processes of games through discussion board forum demands, fund-raising campaigns to persuade companies to change or add game content, and modifications (“modding”) of the games through fan-created downloads. The result has changed the way we understand the interactive nature of digital games and the power of fan culture to shape those games. Source: Publishe
Incentives for Fertilizer Use in Sub-Saharan Africa: A Review of Empirical Evidence on Fertilizer Response and Profitability
No full textThis research addresses two questions: Why is fertilizer not yet fulfilling its potential as a major stimulus to agricultural productivity in SSA? What can be done to improve the situation? Our answers are based on an extensive review of fertilizer response, profitability, and policy literature as well as some analysis of crop budgets and aggregate national statistics on fertilizer consumption. Much of the debate about fertilizer use in SSA focuses on two issues: whether the profit incentive is adequate and, if so, whether farmers have the capacity to access and use it.food security, food policy, fertilizer use, sub-Saharan Africa, Crop Production/Industries, Downloads May 2008-July 2009: 153, Q18,
PROSPECTUS at LAABF Printed Matter's Los Angeles Art Book Fair
No full textFRIENDLY FIRE
PROSPECTUS
With the launch of PROSPECTUS (Artschool/UK 2013), the publishing collective (Verina Gfader, John Reardon, Ruth Höflich) initiates a series of post-PROSPECTUS events and actions for LAABF 2014, including panel discussion and reading in the Classroom, production of flag, and distribution of posters via their book in the Friendly Fire section. Posters by Paul Bailey, David Blamey, Gürsoy Doğtaş, Samuel Dowd, Oliver Lerone Schultz, Ruth Maclennan and Simon O'Sullivan ... Artschool/UK is a self-organised artistic entity based in London.
www.artschooluk.org
The Classroom
After five years at the NY Art Book Fair, The Classroom makes its inaugural trip to the west coast for LAABF14. This curated series of informal conversations, workshops, readings and other artist-led programs is also an informal venue for artists, writers and publishers to feature new releases and present their publications, organised by David Senior of the Museum of Modern Art Library. Located in Gallery D.
FRIDAY, JANUARY 31
11:00 am - 1:00 pm
PRO–SPECTUS: Materials of the Future – How can we speculate
In conjunction with the launch of PROSPECTUS (ARTSCHOOL/UK, 2013), the publishing collective moderates a discursive event, expanding the topics of the book around academies and factories, art schooling and extra-institutional frameworks, into new enquiries of future materials. Themes of secondary knowledge, wildflower poetries, botanical diasporas, artistic agency and experimental analytical models, are addressed in a mix of informal panel discussion, poster distribution, reading and screening, including Fritz Haeg, Mark Allen of Machine Project, Johnnie JungleGuts / Kchung community radio station, and P.collective (John Reardon, Verina Gfader, Ruth Höflich). A limited edition flag by Ruth Höflich will be produced to coincide with the event
Improved outcomes associated with maximal extent of resection for butterfly glioblastoma: insights from institutional and national data
No full textBackground Butterfly glioblastomas (bGBMs) are grade IV gliomas that infiltrate the corpus callosum and spread to bilateral cerebral hemispheres. Due to the rarity of cases, there is a dearth of information in existing literature. Herein, we evaluate clinical and genetic characteristics, associated predictors, and survival outcomes in an institutional series and compare them to a national cohort. Methods We identified all adult patients with bGBM treated at Brigham & Women's Hospital (2008-2018). The National Cancer Database (NCDB) was also queried for bGBM patients. Survival was analyzed with Kaplan-Meier methods, and Cox models were built to assess for predictive factors. Results Of 993 glioblastoma patients, 62 cases (6.2%) of bGBM were identified. Craniotomy for resection was attempted in 26 patients (41.9%), with a median volumetric extent of resection (vEOR) of 72.3% (95% confidence interval [95%CI] 58.3-82.1). The IDH1 R132H mutation was detected in two patients (3.2%), and MGMT promoter was methylated in 55.5% of the assessed cases. In multivariable regression, factors predictive of longer OS were increased vEOR, MGMT promoter methylation, and receipt of adjuvant therapy. Median OS for the resected cases was 11.5 months (95%CI 7.7-18.8) vs. 6.3 (95%CI 5.1-8.9) for the biopsied. Of 21,353 GBMs, 719 (3.37%) bGBM patients were identified in the NCDB. Resection was more likely to be pursued in recent years, and GTR was independently associated with prolonged OS (p < 0.01). Conclusion Surgical resection followed by adjuvant chemoradiation is associated with significant survival gains and should be pursued in carefully selected bGBM patients
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