4,907 research outputs found
Exploring small area demand for grocery retailers in tourist areas
No full textNewing, A., Clarke, G.P. and Clarke, M. 2014. Exploring small area demand for grocery retailers in tourist areas. Tourism Economics, 20(2), pp.407-427This paper uses data from a major loyalty card scheme to draw insights about the characteristics of grocery expenditure by tourists. The authors explore the volume, value and composition of store based visitor expenditure using consumer data from the loyalty card scheme. They focus on grocery spending at selected stores in Cornwall, a popular tourist destination in South West England. Theloyalty card data provide a valuable source rarely available for academic investigations. The authors are able to analyse visitor spend by socio-economic and geodemographic characteristics, drawing a range of comparisons with residential demand from within the store catchment areas. They demonstrate that visitor grocery expenditure is complex and varies by store, destination and type of customer. The paper presents evidence to suggest that the current approaches used to estimate sales uplift and local-level economic impact from visitor demand are unable to account for the complexities of this form of expenditure. Based on these insights, the authors recommend that sophisticated modelling is employed to estimate the impact of visitor expenditure
Determining the Location of the Alpha-Synuclein Dimer Interface using Native Top-Down Fragmentation and Isotope Depletion-Mass Spectrometry
No full textAlpha-synuclein (αSyn), a 140-residue intrinsically disordered protein, comprises the primary proteinaceous component of pathology-associated Lewy body inclusions in Parkinson’s disease (PD). Due to its association with PD αSyn is studied extensively; however the endogenous structure and physiological roles of this protein are yet to be fully understood. Here, ion mobility-mass spectrometry and native top-down electron capture dissociation fragmentation have been used to elucidate the structural properties associated with a stable, naturally-occurring dimeric species of αSyn. This stable dimer appears in both wild-type (WT) αSyn and the PD-associated variant A53E. Furthermore, we integrated a novel method for generating isotopically depleted protein into our native top-down workflow. Isotope depletion increases signal-to-noise ratio and reduces the spectral complexity of fragmentation data, enabling the monoisotopic peak of low abundant fragment ions to be observed. This enables the accurate and confident assignment of fragments unique to the αSyn dimer to be assigned, and structural information about this species to be inferred. Using this approach, we were able to identify fragments unique to the dimer, which demonstrates a C-terminal to C-terminal interaction between the monomer subunits. The approach in this study holds promise for further investigation into the structural properties of endogenous multimeric species of αSyn. The data relates to the following publication:
Kiani Jeacock, Alexandre Chappard, Kelly J. Gallagher, C. Logan Mackay, David P. A. Kilgour, Mathew H. Horrocks, Tilo Kunath and David J. Clarke. 'Determining the Location of the Alpha-Synuclein Dimer Interface using Native Top-Down Fragmentation and Isotope Depletion-Mass Spectrometry.' J. Am. Soc Mass Spec. (in submission)
Replacement Names for <i>Elwoodius</i> Clarke & Oberprieler and <i>Platychirus</i> Clarke & Oberprieler (Coleoptera: Curculionoidea: Mesophyletidae)
No full textIn a recent paper we published on the weevil fauna preserved in Burmese amber, two newly proposed generic names were subsequently identified as preoccupied names (Elwoodius Clarke & Oberprieler and Platychirus Clarke & Oberprieler). We propose the name Zimmiorhinus as a replacement name for Elwoodius Clarke & Oberprieler and Burmophyletis as a replacement name for Platychirus Clarke & Oberprieler
Unwell: A Study on the Perception of Black and Aged Bodies, McKenzie Clarke, Spring 2020
No full textMckenzie Clarke is a rising senior from Murfreeboro, Tennessee. Her professional goal is to become a tenured professor of English
Learning to See: A Reflection on Intergenerational Experiences, McKenzie Clarke, Spring 2020
No full textMckenzie Clarke is a rising senior from Murfreeboro, Tennessee. Her professional goal is to become a tenured professor of English
Agnosthaetus leviceps Clarke 2011, new species
No full text(17) Agnosthaetus leviceps Clarke, new species (Figs. 137–139, Map 4) Type Material. Holotype. ♂, with four labels: " New Zealand SL| 2km SW Longwood | Trig [46°13.602′S, 167°50.292′E] 610m | Longwood Ra| 1 Feb 1976 / L.L. Deitz | moss in forest| 76/11/ FMNH-INS 0000 038 382 / HOLOTYPE Agnosthaetus leviceps Clarke, ♂, design. D. Clarke 2011", in NZAC. Paratypes. 2 specimens (2♂). Same data as holotype, 2♂, FMNH-INS 38380–381 (in NZAC). Diagnosis. Agnosthaetus leviceps may be distinguished from all other known Agnosthaetus species by the combination of lack of punctures on the dorsum of the head (cf. A. nitidus, with indistinct punctures), medial pronotal sulcus separated from both anterior setal puncture and basal fovea (Fig. 24, ap, bf; similar to A. vicinus: Fig. 75), incomplete to largely effaced lateral pronotal carina (similar to Fig. 80, pc), and absence of an elytral sutural stria. The aedeagus differs from all others with aedeagus " Type A" in having copious, long apicomedial setae on the median lobe (Fig. 139). Description. Color: Attractive, pale brown, and shiny species. Head: Frontal ridge absent. Dorsum impunctate on disc; with distinct shallow punctures only posterolaterally. Dorsal microsculpture absent. Dorsal tentorial sulcus (cf. Figs. 10–11, dt) broadly ovate. Sublongitudinal ridge (cf. Fig. 10, sr) distinct; not confused by smaller carinae or punctures; crest at antennal tubercle without distinct microsculpture. Area above and behind antennoocular carina (Figs. 10–11, arrow) with distinct subsidiary carina formed by confluent punctures. Antenno-ocular carina joining eye behind middle (cf. Fig. 59). Temple (Fig. 11, tm) long, greater than 50% EYL. Subocular surface without microsculpture, completely smooth between punctures (cf. Figs. 63–64). Apical labral margin in males moderately broadly and shallowly emarginate medially, evenly dentate, with 16–18 teeth (n =3), all teeth normal, projecting more or less anteriorly (Fig. 137). Adoral labral surface in males smooth, without subapical transverse ridge. Mandible more or less identical in both sexes; males with single, mesially directed tooth, without preapical spur (cf. Fig. 189); females with single, mesially projecting tooth, without spur. Prothorax: Pronotum without microsculpture. Medial pronotal sulci anteriorly separate from, and terminating posterior to anterior punctures; basally distant from remnant basal foveae (cf. Fig. 75). Distance between medial sulci slightly greater posteriorly. Lateral pronotal sulcus partly to completely interrupted at middle (cf. Figs. 77, 80, ls). Pronotal basolateral carina present, but only weakly developed. Base of pronotum without pair of median foveae (cf. Fig. 75); without lateral foveae, or with single distinct lateral fovea. Pronotal macrosetal punctures absent (cf. Fig. 77). Medial pronotal seta adjacent to lateral sulcus (cf. Fig. 77). Lateral pronotal carina, anteriorly complete, continuous with anterior pronotal margin and incomplete, usually more or less completely absent beyond middle of pronotum, if present anteriorly then difficult to discern even at high magnification (cf. Fig. 80, pc). Pronotal hypomeron (Fig. 24, hy) shiny, without microsculpture. Prosternum (Fig. 24, pro) impunctate; with distinctly reticulate microsculpture. Pterothorax: Elytron (Fig. 23, e) without microsculpture; without sutural stria; without macrosetae; laterally with single ridge (cf. Fig. 24, ek). Mesothoracic epimeral region (Fig. 24, mer) shiny, without microsculpture. Metathoracic pleural region (Fig. 24, m) shiny, without microsculpture. Metathoracic pleural ridge absent (cf. Fig. 86); metathoracic pleural groove (Fig. 24, gr) complete, continuing to or near to pleurocoxal articulation. Abdomen: Abdominal vestiture short, somewhat appressed, dorsally more or less evenly projecting posteriorly. Abdominal sternite VI of male with setose apicomedial protuberance. Aedeagus (Fig. 138): " Type A" (see description on p. 8). Apical part of median lobe with rounded lateral lobes and abruptly distinct, broadly acuminate, sharply pointed apicomedian lobe. Apicolateral setae small; apicomedial setae up to 10X longer than apicolateral setae (Fig. 139). Paramere extending to about level of median lobe apex; in lateral view produced apically into lobe; in dorsal view with outer side gently convex; with 4 large setae at apex. Etymology. The specific epithet leviceps is a noun in apposition from the Latin levis (smooth) combined with ceps (head) in reference to the unique lack of punctation on the dorsum of the head. Distribution. (Map 4). South Island: SL. Remarks. The holotype and paratypes of this species share some unusual and otherwise unique pronotal characters with A. nitidus and A. vicinus. From both of these species, A. leviceps can be distinguished most easily by the lack of the elytral sutural stria. The male secondary sexual character on abdominal sternite VI is a unique structure within Agnosthaetus.Published as part of Clarke, Dave J., 2011, A Revision of the New Zealand Endemic Rove Beetle Genus Agnosthaetus Bernhauer (Coleoptera: Staphylinidae), pp. 1-118 in The Coleopterists Bulletin (mo 10) (mo 10) 2011 on page 47, DOI: 10.1649/0010-065X-65.mo4.1, http://zenodo.org/record/490708
What the News Taught Me About Age and Ageism I Did Not Know, McKenzie Clarke, Spring 2020
No full textMckenzie Clarke is a rising senior from Murfreeboro, Tennessee. Her professional goal is to become a tenured professor of English
What Mrs. Callie Terrell Taught Me About Strength and Fragility That I Did Not Know, McKenzie Clarke, Spring 2020
No full textMckenzie Clarke is a rising senior from Murfreeboro, Tennessee. Her professional goal is to become a tenured professor of English
Figs. 121–124 in A Revision of the New Zealand Endemic Rove Beetle Genus Agnosthaetus Bernhauer (Coleoptera: Staphylinidae)
No full textFigs. 121–124. Aedeagi of species in the Agnosthaetus brouni species-group, dorsal (left) and right lateral (right) views. 121) A. brouni; 122) A. tumidus; 123) A. aequalis; 124) A. akatarawa. Scale bar = 100 mm.Published as part of Clarke, Dave J., 2011, A Revision of the New Zealand Endemic Rove Beetle Genus Agnosthaetus Bernhauer (Coleoptera: Staphylinidae), pp. 1-118 in The Coleopterists Bulletin (mo10) 2011 on page 94, DOI: 10.1649/0010-065X-65.mo4.1, http://zenodo.org/record/490708
Ted Clarke Interview, July 23, 2021
No full textTed Clarke discusses being born in Eureka, Montana and living in the “new” town of Rexford after Lake Koocanusa inundated their home during the Kootenai Dam construction. Ted remembers being 11 in 1955 when his dad, Ed, became the lookout at Webb Mountain Lookout above Eureka. Ted recalls his first experience with pack trains; hauling water from a spring ¼-mile below the lookout, sleeping with younger brother, Dave on the lookout floor; and learning to help with duties like using the alidade, taking the weather, and watching for storms. He tells of brother Dave and him gathering huckleberries and morel mushrooms; having squirrels, crows, and a dog as pets; playing with slingshots; and fishing Boulder Lake. Ted says he and Dave made their own “slide” (a zip line) out of #9 copper wire with a galvanized pipe as a handle. Ted remembers one rainstorm with the lightning protection humming and forming an electrical charge as big as a volleyball. He remembers the family each taking one side of the lookout recording lightning strikes for several hours. Ted recalls his father getting a job on Black Butte Lookout when Ted was 14. The family stayed there until his dad died in 1964. Ted tells of working for the U.S. Forest Service for a short while on Red Mountain Lookout in his teen years.https://scholarworks.umt.edu/nwmt-ffla/1014/thumbnail.jp
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