471 research outputs found
COMMIPHORA MUKUL EXTRACT AND GUGGULSTERONE EXHIBIT ANTITUMOUR ACTIVITY THROUGH INHIBITION OF CYCLIN D1, NF-Κβ AND INDUCTION OF APOPTOSIS IN ORAL CANCER CELLS
No full textComiphora mukul, a promising medicinal plant and its constituent Guggulsterone (GS) is used in Ayurveda since decades. This study was aimed to investigate the anticancer potential of C. mukul and GS on oral cancer cell lines (SCC-4, KB). MTT assay was used to determine tumour cell proliferation, propidium iodide labeling and annexin V- binding, followed by flow cytometry was used to determine cell cycle and apoptosis of tumor cells after treatment. Expression of regulatory proteins such as NF-κß, cyclin D1, p53 and vascular endothelial growth factor was determined by western blot. C. mukul and GS significantly inhibited tumor cell growth, caused cell cycle arrest and apoptosis in both tumor cells. Such activities appeared to be due to inhibition of NF-κß, cyclin D1and restoration of p53. Overall our data suggests that C. mukul and GS may be developed as chemopreventive and chemotherapeutic drug for oral cancer
From Bengal to Japan : The Impact of Mukul Chandra Dey on Indo-Japanese Art Interactions
No full textIn: Moinuddin Mohammad, Kokado Minori eds. Reconceptualizing Cross-Border Academic Mobility in the Interdisciplinary Research Agenda, International Affairs Office, School of Letters/Graduate School of Humanities, The University of Osaka, 2025, 93p.Mukul Chandra Dey (1895-1985), a pioneering Indian artist, played a crucial role in this transnational cultural exchange. Dey, one of the first Indian artists to study in Japan, deeply engaged with traditional Japanese woodcut printing techniques, incorporating them into his own artistic practices. His work represents a unique synthesis of Japanese aesthetics and Indian sensibilities, contributing to the evolution of modern Indian art. Despite his significant contributions, Dey's role in this cultural interaction has been largely overlooked in both Indian and Japanese art history. This research seeks to address the underrepresentation of Mukul Dey's contributions by re-examining his work within the context of Indo-Japanese cultural relations. By focusing on Dey’s engagement with Japanese art and its influence on his oeuvre, this study fills a critical gap in the scholarship, offering new insights into the artistic exchanges that shaped modern cultural landscapes in both India and Japan. Dey's work stands as a testament to the deep and enduring connection between the two nations
Recent developments in rare-earths doped nano-engineered glass based optical fibers for high power fiber lasers
No full textRecent advances of development of rare-earth (RE) doped optical fibers have become increasingly important due to their applications in various optoelectronic devices such as high power optical fiber amplifiers, fiber lasers, etc. We present a review of recent progress on development of RE-doped glass host based optical fiber materials with special emphasis on large mode area fibers for efficient laser and amplifier. The challenging task is to manage high power inside the active core otherwise output power instability would affect the beam quality. Best solution is to use suitable dopants in addition to active elements during the process of fabrication. Modified chemical vapour deposition (MCVD) process combined with solution doping technique is deployed to develop RE-doped nano-engineered glass based optical fibers through suitable thermal annealing of optical preforms. The developed doped fibers are characterized by DTA, TEM, XRD, XAS, EPMA and EXAFS to assess the structural parameters. This new class of optical fiber materials will open up new possibilities for extended functionality and greater optoelectronic integration
Caste and Nature
No full textRarely do Indian environmental discourses examine nature through the lens of caste. Whereas nature is considered as universal and inherent, caste is understood as a constructed historical and social entity. Mukul Sharma shows how caste and nature are intimately connected. He compares Dalit meanings of environment to ideas and practices of neo-Brahmanism and certain mainstreams of environmental thought. Showing how Dalit experiences of environment are ridden with metaphors of pollution, impurity, and dirt, the author is able to bring forth new dimensions on both environment and Dalits, without valourizing the latter’s standpoint. Rather than looking for a coherent understanding of their ecology, the book explores the diverse and rich intellectual resources of Dalits, such as movements, songs, myths, memories, and metaphors around nature. These reveal their quest to define themselves in caste-ridden nature and building a form of environmentalism free from the burdens of caste. The Dalits also pose a critical challenge to Indian environmentalism, which has, until now, marginalized such linkages between caste and nature.</p
Evaluating levy flight parameters for random searches in a 2D space
No full textThesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2013.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (pag 23).It is experimentally known that the flight lengths of random searches by foragers such as honey bees statistically belong to a power law distribution. Optimality of such random searches has been a topic of extensive research because knowing their optimal parameters may help applied sciences. Viswanathan et al. have shown the inverse-square power law to be the optimal law for such random searches. This thesis explores the capability of the model presented in such that it can be applied to Unmanned Autonomous Vehicles (UAVs). The thesis also identifies the minimum flight length, lmin, as an important factor that needs to be controlled based on the UAV's sensor range. We present a theoretical lmin as an explicit function of the sensor range, rv, and an estimated target density, p.by Mukul Kumar Singh.S.B
Nano-engineered glass based optical fiber for fiber laser
No full textWe have developed the technology for making of dielectric nano-particles doped nano-engineered glass based optical fibers. Two kinds of dielectric nano-particles (DNP) containing silica glass based Yb2O3 doped fibers are made successfully through solution doping (SD) technique. One: Yb2O3 doped yttria-rich alumino-silica nano-particles based optical fiber developed during drawing of D-shaped low RI resin coated large mode area (LMA) optical fiber from the modified preform which annealed at 1450-1550°C for 3 hours under heating and cooling rates of 20°C/min and other: Yb2O3 doped zirconia-germanium-alumino (ZGA) rich yttria-silica nano-particles based optical fibers developed during drawing of normal RI coated single mode optical fiber from the modified preform which annealed at 1000-1100°C for 3 hours under heating and cooling rates of 20°C/min. Fabrication of Yb2O3 doped yttria-rich alumino-silica nano-particles based D-shaped low RI coated large core optical fibers having core diameter around 20.0-30.0 micron was made. The size of DNP nano-particles was maintained within 5-10 nm under doping of 0.20 mole of fluorine. The start fiber preforms are studied by means of EPMA, EDX, and electron diffraction analyses, revealing phase-separated nano-sized ytterbium-rich areas in their cores. There is a great need to engineer the composition as well as doping levels of different elements within the core glass during the preform making stages to generate phase-separated Yb 2O3 doped DNP nano particles in the fiber. The matter concentrates on making of Yb2O3 doped DNP containing optical fibers along with material characterizations, study of spectroscopic properties, photo-darkening phenomena and lasing characteristics. Such kind of nano-engineered glass based optical fibers shows good lasing efficiency with improved photodarkening phenomena compared to the standard silica glass based fiber. © 2012 IEEE
Multicore optical fibers for multi-band laser and amplifier
No full textWe report the fabrication and characterisation of rare-earth-doped multicore optical fiber with the aim to develop multi-band optical fiber laser sources and amplifiers to exploit future novel multicore fiber laser and amplifiers.</p
Author Correction: Native diversity buffers against severity of non-native tree invasions (Nature, (2023), 621, 7980, (773-781), 10.1038/s41586-023-06440-7)
No full textCorrection to: Nature Published online 23 August 2023 In the version of the article initially published, Stanislaw Miscicki’s name incorrectly appeared as Miscicki Stanislaw. Additionally, the affiliation for Thomas T. Ibanez has been updated to “AMAP, University of Montpellier, CIRAD, CNRS, INRAE, IRD, Montpellier, France”, and the second affiliation for Sharif A. Mukul has been updated to “Department of Environment and Development Studies, United International University, Dhaka, Bangladesh”. The corrections have been made to the HTML and PDF versions of the article. © 2023, The Author(s)
Full transcript: Agyeya and the multitudes he contained
No full textAuthor and journalist Akshaya Mukul has recently published a book about the Hindi writer Sachchidananda Hirananda Vatsyayan, better known as Agyeya, titled Writer, Rebel, Soldier, Lover: The Many Lives of Agyeya. The following is a transcript of an interview with Mukul, conducted by Trisha Gupta, journalist, critic and professor at the Jindal School of Journalism and Communication”?. They discuss the book and the ‘multitudes’ that the writer contained. The following is a transcript of the interview. It has been edited for style and clarity
Problems in Task Scheduling in Multiprocessor System
No full textThis Contemporary computer systems are multiprocessor or multicomputer machines. Their efficiency depends on good methods of administering the executed works. Fast processing of a parallel application is possible only when its parts are appropriately ordered in time and space. This calls for efficient scheduling policies in parallel computer systems. In this work deterministic problems of scheduling are considered. The classical scheduling theory assumed that the application in any moment of time is executed by only one processor. This assumption has been weakened recently, especially in the context of parallel and distributed computer systems. This monograph is devoted to problems of deterministic scheduling applications or tasks according to the scheduling terminology requiring more than one processor simultaneously. We name such applications multiprocessor tasks. In this work the complexity of open multiprocessor task scheduling problems has been established. Algorithms for scheduling multiprocessor tasks on parallel and dedicated processors are proposed. For a special case of applications with regular structure which allow for dividing it into parts of arbitrary size processed independently in parallel, a method of finding optimal scattering of work in a distributed computer system is proposed. The applications with such regular characteristics are called divisible tasks. The concept of a divisible task enables creation of tractable computation models in a wide class of computer architectures such as chains, stars, meshes, hypercubes, multistage networks. Divisible task method gives rise to the evaluation of computer system performance. Examples of such performance evaluation are presented. This work summarizes earlier works of the author as well as contains new original results. Mukul Varshney | Jyotsna | Abhakiran Rajpoot | Shivani Garg "Problems in Task Scheduling in Multiprocessor System" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-1 | Issue-4 , June 2017, URL: https://www.ijtsrd.com/papers/ijtsrd2198.pd
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