162 research outputs found

    Bilateral and unilateral arm training improve motor function through differing neuroplastic mechanisms: a single-blinded randomized controlled trial

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    BACKGROUND AND PURPOSE: This randomized controlled trial tests the efficacy of bilateral arm training with rhythmic auditory cueing (BATRAC) versus dose-matched therapeutic exercises (DMTEs) on upper-extremity (UE) function in stroke survivors and uses functional magnetic resonance imaging (fMRI) to examine effects on cortical reorganization. METHODS: A total of 111 adults with chronic UE paresis were randomized to 6 weeks (3×/week) of BATRAC or DMTE. Primary end points of UE assessments of Fugl-Meyer UE Test (FM) and modified Wolf Motor Function Test Time (WT) were performed 6 weeks prior to and at baseline, after training, and 4 months later. Pretraining and posttraining, fMRI for UE movement was evaluated in 17 BATRAC and 21 DMTE participants. RESULTS: The improvements in UE function (BATRAC: FM Δ = 1.1 + 0.5, P = .03; WT Δ = -2.6 + 0.8, P < .00; DMTE: FM Δ = 1.9 + 0.4, P < .00; WT Δ = -1.6 + 0.7; P = .04) were comparable between groups and retained after 4 months. Satisfaction was higher after BATRAC than DMTE (P = .003). BATRAC led to significantly higher increase in activation in ipsilesional precentral, anterior cingulate and postcentral gyri, and supplementary motor area and contralesional superior frontal gyrus (P < .05). Activation change in the latter was correlated with improvement in the WMFT (P = .01). CONCLUSIONS: BATRAC is not superior to DMTE, but both rehabilitation programs durably improve motor function for individuals with chronic UE hemiparesis and with varied deficit severity. Adaptations in brain activation are greater after BATRAC than DMTE, suggesting that given similar benefits to motor function, these therapies operate through different mechanisms

    Spatial distribution of diuron sorption affinity as affected by soil, terrain and management practices in an intensively managed apple orchard

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    We investigated how the sorption affinity of diuron (3'-(3,4-dichlorophenyl)-1,1-dimenthyl-urea), a moderately hydrophobic herbicide, is affected by soil properties, topography and management practices in an intensively managed orchard system. Soil-landscape analysis was carried out in an apple orchard which had a strong texture contrast soil and a landform with relief difference of 50 m. Diuron sorption (K(d)) affinity was successfully predicted (R(2)=0.79; p<0.001) using a mid-infrared - partial least squares model and calibrated against measured data using a conventional batch sorption technique. Soil and terrain properties explained 75% of the variance of diuron K(d) with TOC, pH(w), slope and WI as key variables. Mean diuron K(d) values were also significantly different (p<0.05) between alley and tree line and between the different management zones. Soil in the tree line generally had lower sorption capacity for diuron than soil in the alleys. Younger stands, which were found to have lower TOC than in the older stands, also had lower diuron K(d) values. In intensively managed orchards, sorption affinity of pesticides to soils was not only affected by soil properties and terrain attributes but also by management regime.Beng P. Umali, Danielle P. Oliver, Bertram Ostendorf, Sean Forrester, David J. Chittleborough, John L. Hutson and Rai S. Kookan

    "Montgomery and his Legions:" A Study of Operational Development, Innovation and Command in 21st Army Group, North-West Europe, 1944-45

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    This thesis considers armour and infantry unit organization and structure in the British Army during the Second World War, specifically in Montgomery's 21st Army Group in North-West Europe. The strengths and weaknesses of how corps and divisions responded to Montgomery's command system - and in particular the commonality of doctrinal practice - has become an issue of debate among historians. This thesis examines and analyses the factors that produced both an effective weapon and a functional doctrine for combining armour and infantry. It does this by tracking how 21st Army Group moved from 'anarchy' to 'problem solving' under Montgomery's direction. It shows that far from being either authoritarian or anarchic, Montgomery's ultimate command system actually encouraged commanders to use their initiative within the goals set out by Montgomery in late 1944 in a series of pamphlets. He believed in the imposition of doctrine, but this overlooks mid-July to end-of-September 1944 when he was open to the "bubble-up" of new ideas: albeit post-pamphlets the subsequent price of uniformity of doctrine was a certain apparent inflexibility. By late 1944 when Montgomery's 21st Army Group "stood at the door of Germany", armour-infantry co-operation practice is shown to have involved the coordination of armour originally intended to play different roles; infantry, and artillery on the basis of commonly agreed upon understandings which had been reached by an essentially collaborative process. Once set out in Montgomery's pamphlets, however, no deviation from this framework was subsequently permitted. Simultaneously, success in action depended on commanders exercising their initiative to be proactive to a greater extent than has hitherto been suggested: Montgomery wanted to constrain choices yet he allowed armoured commanders enough freedom of action to respond to challenges within the "master plan". This thesis thus makes an original contribution to the debate on Montgomery's command style, and its consequences, and more widely on the role of a great commander

    Social networks: the future of marketing for small business

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    Purpose – The authors review recent developments in online marketing strategy that demonstrate the growing power of online communities in building brand reputations and customer relationships. Design/methodologies/approach – This work draws upon the results of an ongoing research project that is investigating the use of new technologies by entrepreneurial growing businesses in the London area. A range of examples from our 30 case study businesses are drawn upon to illustrate some of the opportunities and threats associated with these new marketing priorities.<br/

    Outsourcing the Business Services

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    The nowadays international market of outsourcing services is relatively mature and with age comes wisdom ... Thus, on a grown market, choosing to outsource services can not only be justified by the strive to reduce costs but it aims to meeting more advanced objectives as accurate alignment with business strategies of the enterprise. As a result, outsourcing has reached new forms of expression that can help the enterprises to gain competitive advantage. In the context of a grown market, a new concept appears, namely the multisourcing which it refers to the outsourcing model of the future [1] that businesses must prepare to accept and use. This concept or model of the future refers to working with several suppliers, which are competitors in a spirit of trust and teamwork, in a collaborative process to maximize the benefits associated with outsourcing process.Business Outsourcing, Audit, Economic and Financial Analysis, Information Technology Outsourcing
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