112 research outputs found
Breve Análise De Um Romance Regional Alemão: Das Neckartreiben Da Autora Sybille Baecker
No full textIn this article will be made a brief presentation of the german regional detective story Neckartreiben of the german author Sybille Baecker. German regional crime stories narrate a crime, but also make the presentation of the region where it takes place, in this case the city of Tübingen and its region.Neste artigo será feita uma breve apresentação do romance policial regional alemão Neckartreiben da autora alemã Sybille Baecker. Os policiais regionais alemães narram um crime, mas também fazem a apresentação da região onde o mesmo tem lugar, neste caso da cidade de Tübingen e a sua região
Symposion Autorschaft
No full textDas Symposion über Autorschaft schließt an das Symposion über Plagiate (Heft 4/2022) an. Es geht um das Verhältnis von Autor und Text, Text und Gegenstand, Text und Leser:in. Wann ist es sinnvoll und erlaubt, mit dem Personalpronomen ›Ich‹ die Autorschaft in einem Text auch explizit zu machen, fragt Paula-Irene Villa. Maren Lehmann entwirft eine Soziologie der Personalisierung, die sich vor einer Subjektivierung hüten muss, auf die dennoch nicht verzichtet werden kann. In welchen blinden Flecken bewegt sich eine Autor:in, die sich postkolonial engagiert, fragt Manuela Boatcă. Und Dirk Baecker diskutiert die Frage, inwiefern ein Text und sein/e Autor:in Teil der sozialen Wirklichkeit sind, von denen sie handeln.
The symposium on authorship follows on from the symposium on plagiarism (issue 4/2022). It deals with the relationship between author and text, text and subject, text and reader. Paula-Irene Villa asks when it makes sense and is permissible to use the personal pronoun ›I‹ to make authorship explicit in a text. Maren Lehmann drafts a sociology of personalization that must be wary of subjectification, which nevertheless cannot be dispensed with. Manuela Boatcă asks what blind spots an author who engages in postcolonialism finds themselves in. And Dirk Baecker discusses the question of the extent to which a text and its author(s) are part of the social reality they deal with
Response to Dual Antiplatelet Therapy in Patients with Peripheral Artery Occlusive Disease Suffering from Critical Limb Ischemia
No full textBackground: Failure to reach the level of therapeutic anticoagulation represents a risk factor for occlusive events in patients suffering from peripheral arterial disease. Our study aimed to analyze the prevalence of nonresponse to dual antiplatelet therapy in a group of patients admitted to our hospital with critical limb ischemia (CLI) following stent-thrombosis. Methods: This prospective study was approved by the local Ethics Review Board. Patients with critical limb ischemia following stent thrombosis were included if dual antiplatelet therapy consisting of 100 mg aspirin and 75 mg clopidogrel per day had been administered over three months prior to enrollment. The antiaggregatory effects were analyzed using the Multiple Electrode Aggregometry (MEA, Multiplate (R), Roche AG, Grenzach, Germany). The primary endpoints were the area under the aggregation curve (AUC) of the ex-vivo-induced platelet aggregation following stimulation with adenosine diphosphate (ADP, ADPtest) and arachidonic acid (ASPItest). Results: Sixty patients were enrolled in this study. Platelet aggregation was 39.6 (24/54) [median (25th/75th percentile)] U in the ADPtest and 22.4 (13/35) U in the ASPItest. Effective aspirin- and ADP-induced therapeutic inhibition of platelet aggregation was confirmed in 78% and 53% of our patients, respectively. Effective dual platelet inhibition was achieved in 27 patients (45%). A non-response to both of the antiaggregatory drugs was found in 14% of the patients. Conclusions: The results of the present study indicate a high prevalence of nonresponse to antiaggregatory medication in our study collective. Further studies are needed to confirm our hypothesis that individual adjustments of both aspirin and clopidogrel dosages may potentially reduce the incidence of CLI in patients suffering from peripheral arterial occlusive disease.University of Frankfur
Introducing Audio Podcasts into a Practical Laboratory Course for Pharmacy Students as a Novel Tool for Performance Assessment
No full textThe use of digital tools can positively impact higher education for both scholars and faculty. In recent years, it has become apparent that podcasts are a suitable medium for use in teaching. They are provided almost exclusively by lecturers for students, with students passively listening to them rather than actively participating in their production. However, this could also be valuable for students. Therefore, this pilot study investigated the extent to which the creation of a podcast would be accepted by students as a method for capturing pharmacy students’ understanding of the learning content. The evaluation was performed as part of the “Clinical Chemistry” practical course, which was attended by third-year pharmacy students in groups of three. After passing the station dealing with practical clinical chemistry relevant diagnostic systems, the groups were asked to produce an educational podcast covering the essential content on the topics of urine test strips or pulse oximetry, respectively. Student attitudes toward the adoption of podcasts as a tool for performance assessment were determined with an anonymous and voluntary survey. The respondents reported that they had fun creating the podcast, which enabled them to look at the instructional content from a different perspective. Competencies such as social and communication skills and media literacy as well as self-organized and self-directed learning were also promoted. However, the students assumed that the tool is not ideally suited for dealing with extensive topics. Nonetheless, the students clearly support the continued creation of podcasts as a performance assessment tool. In addition, they suggest integrating podcasts into other courses within the pharmacy curriculum. This may also be related to the infrequent use of novel technologies, such as podcasts, in their education thus far
Die Erneuerung des Gewohnten: Thesen zur Kultur- und Kreativwirtschaft
No full textDirk Baecker Kultur- und Kreativwirtschaft ist ein Sammelbegriff zur Bezeichnung von Aktivitäten, die eine Gesellschaft kulturell und kreativ bewirtschaften. ((Sei es erwerbswirtschaftlich, in privater oder staatlicher Trägerschaft, siehe Michael Söndermann, Christoph Backes, Olaf Arndt und Daniel Brünink, Kultur- und Kreativwirtschaft: Ermittlung der gemeinsamen charakteristischen Definitionselemente der heterogenen Teilbereiche der „Kulturwirtschaft“ zur Bestimmung ihrer Perspektiven aus ..
Ernährung im Spannungsfeld von Natürlichkeit und technischer Innovation: Eine kultursoziologische Beobachtung von Kommunikationen über Ökolebensmittel und High-Tech-Food
No full textErnährung im Spannungsfeld von Natürlichkeit und technischer Innovation: Eine kultursoziologische Beobachtung von Kommunikationen über Ökolebensmittel und High-Tech-Food
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General Applicability of High-Resolution Continuum-Source Graphite Furnace Molecular Absorption Spectrometry to the Quantification of Oligopeptides Using the Example of Glutathione
No full textThis communication introduces the first-time application of high-resolution continuum-source molecular absorption spectrometry (HR CS MAS) for the quantification of a peptide. The graphite furnace technique was employed and the tripeptide glutathione (GSH) served as a model compound. Based on measuring sulfur in terms of carbon monosulfide (CS), a method was elaborated to analyze aqueous solutions of GSH. The most prominent wavelength of the CS molecule occurred at 258.0560 nm and was adduced for monitoring. The methodological development covered the optimization of the pyrolysis and vaporization temperatures. These were found optimally to be 250 °C and 2250 °C, respectively. Moreover, the effect of modifiers (zirconium, calcium, magnesium, palladium) on the absorption signals was investigated. The best results were obtained after permanent coating of the graphite tube with zirconium (total amount of 400 μg) and adding a combination of palladium (10 µL, 10 g L−1) and calcium (2 µL, 1 g L−1) as a chemical modifier to the probes (10 µL). Aqueous standard samples of GSH were used for the calibration. It showed a linear range of 2.5–100 µg mL−1 sulfur contained in GSH with a correlation coefficient R2 > 0.997. The developed method exhibited a limit of detection (LOD) and quantification (LOQ) of 2.1 µg mL−1 and 4.3 µg mL−1 sulfur, respectively. The characteristic mass accounted for 5.9 ng sulfur. The method confirmed the general suitability of MAS for the analysis of an oligopeptide. Thus, this study serves as groundwork for further development in order to extend the application of classical atomic absorption spectrometry (AAS)
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