1,036 research outputs found
Ferguson-Smith, Malcolm: transcript of a video interview (06-Jun-2015)
No full textInterview with Professor Malcolm Ferguson-Smith, conducted by Ms Emma M. Jones, for the History of Modern Biomedicine Research Group, 06 June 2015, in Glasgow. Transcribed by Mrs Debra Gee, and edited by Professor Tilli Tansey and Mr Alan Yabsley. The project management was undertaken by Mr Adam Wilkinson. Professor Malcolm Ferguson-Smith (b. 1931) is Emeritus Professor of Pathology, University of Cambridge. He graduated in medicine at Glasgow University in 1955 and, while undertaking postgraduate training there in pathology, was introduced to research on sex chromatin under Bernard Lennox. An interest in Klinefelter’s syndrome in 1957 to 1958 led to his appointment as Fellow in Medicine at Johns Hopkins University, Baltimore, in 1959, where he established the first chromosome diagnostic service in the USA, and undertook cytogenetic research into Turner syndrome. Research interests include molecular cytogenetics, karyotype evolution, vertebrate sex determination and comparative genomics. He is joint author of 'Essential Medical Genetics'.The History of Modern Biomedicine Research Group is funded by the Wellcome Trust, which is a registered charity (no. 210183). The current interview has been funded by the Wellcome Trust Strategic Award entitled “Makers of modern biomedicine: testimonies and legacy” (2012-2017; awarded to Professor Tilli Tansey)
"The honor of firing before His Majesty": Patrick Ferguson's will and the Royal Armouries’ Ferguson rifle
No full textPatrick Ferguson (1744-80) designed the first breech-loading rifle to be used by the British Army. In November 2000, the Royal Armouries purchased an early example, formerly in the possession of the Fergusons of Pitfour, descendants of Patrick's younger brother, George. Patrick Ferguson's will has helped the author identify the Royal Armouries' Ferguson Rifle as the one which Patrick Ferguson used when he demonstrated it before George III and Queen Charlotte at Windsor in 1776
Increasing the region of attraction in DC microgrids
No full textBased on the port-Hamiltonian framework, this paper proposes a novel control scheme for stabilising the voltage in DC networks affected by (i) unknown ZIP-loads, i.e., nonlinear loads consisting of the parallel combination of constant impedance (Z), current (I) and power (P) load types, and (ii) unknown (but bounded) time-varying disturbances. Differently from the results existing in the literature, where restrictive (sufficient) conditions on the load parameters, voltage trajectory and voltage reference are assumed to be satisfied, this is the first paper (to the best of our knowledge) proposing a controller that relaxes such conditions and guarantees the exponential stability of the desired equilibrium point, whose region of attraction can be increased by simply tuning the control gains. In the case the network is affected by unknown time-varying disturbances, local input-to-state stability (l-ISS) is ensured. Furthermore, if non-ideal P-loads are considered, excluding the unrealistic possibility that the load absorbs infinite current when the voltage approaches zero, the aforementioned stability results hold globally.(c) 2023 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
De afsluiting van het Haringvliet
No full textIr. H. A. Ferguson - Ten geleide ** H. J. Stuvel - BoIwerk en hoafdkraan ** Ir. P. Santema - De Haringvlietafsluiting aIs instrument vaor regionalewaterbeheersing in Zuidwest-Nedefland ** Prof. ir. P. A. van de Velde - Het ontwerp in hoofdlijnen vaor de uitwateringssluis ** H. J . Stuvel - De kraan van de Delta ** Ir. J. E. Prins - Haringvlietproject stuwde waterloopkundig ondefzoek naar hager plan ** lr. F. Spaargaren en iT. J. J. Vinje - Waterloopkundig onderzoek ten behoeve van vormgeving kunstwerk, vorm bouwput en vonn sluitgat ** H. J. Stroband, ing. - De'Deltar' ** Ir. P. H. van der Weele- De bodembescherming ter weerszijden van de spuisluizen ** W. Drooger - Mechanisch zinken ** Ir. C. A. ZuMerwijk - 'Grootgrondverzet' in het Haringvliet ** Ir. P. Blokland - De problemen van de schaalvergroting bij het ontwerpen en bouwen van de spnisluis in het Haringvliet ** H. J. Stuvel - De produktie van de nablaliggers ** Ir. A. van Dam en ir. Ph. Diderich - Terugblik op een inspirerende opdracht ** Ir. drs. H. Kuiper - De segmentschuiven met elektro-hydraulische aandrijving ** fr. M. Geleedst en ir. W. A. Venis - OnderLoek naar het dynamisch gedrag van de Haringvlietsluis ** Ir. R.I. Schor - De vervaardiging van de schuiven ** Ir. J. ter Brugge - De montage van de schuiven ** Ir. P. H. van der Weele - De kabelbaan ** Ir. T. G. van der Meer - De sluiling van het Rak van Scheelhoek ** Ir. A. 1. Woestenenk - Bijzondere toerassing van zandasfalt in de waterbouw ** Ir. J.J. Pilon- De Hydrometische begeleiding van de Haringvlietwerken ** W. A. A. van Eyden en ir. F. Langeweg - De functie van de Haringvlietsluizen binnen het waterbeheersingssysteem van het noordelijk Deltabekken ** Prof. ir. P. Ph. Jansen - Een historisch gebeurenDeltawerke
Measuring business value and sustainability performance
No full textThe integration of corporate sustainability within operations remains an important and fundamental challenge for business. This paper first consolidates and then builds upon the EABIS-supported activities of Cranfield School of Management with business practitioners. It focuses on the performance and evaluation criteria relating to determining corporate responsibility (CR) value.
The paper begins by categorising components of CR in terms of decision-making levels and business case requirements. It then describes a methodology for establishing CR issues with the prioritisation of stakeholders before linking this relationship onto business benefits and shareholder value drivers. Using illustrated models and worked examples, sections within the paper provide further practical advice and guidance for developing and populating elements within the framework. Additional sections then complement the application of the CR Value-chain framework, with a chapter on performance measurement that explores the key performance measure characteristics required to underpin the performance element of the framework. The final chapter describes decision-making support tools, such as financial appraisals and risk evaluations, which also underpin the shareholder value approach and should be integrated within this corporate sustainability value management framework.
A key purpose of this approach is to support the integration of sustainability performance management processes and systems within business practice. It explores methods for making more explicit the issues surrounding CR and financial value. It also provides useful approaches for helping businesses select, measure and evaluate performance for internal CR strategies, policies and processes. Some analytical methods are considered for identifying the costs and benefits from sustainability-related issues, projects and new ventures, including discussions with regard to harmonising existing business functions.
This paper serves to provide an early prototype for future approaches towards integrated sustainability performance management systems.The European Academy for Business and Society, IBM, Johnson & Johnson, Microsoft, Shell and Unileve
A high resolution M band study of W3 IRS5
No full textvi, 111 leaves : ill ; 28 cm.Includes bibliographical references (leaves 78-81).This thesis presents an infrared spectral analysis of the high mass protostar W3 IRS5. A high resolution M band spectrum of W3 IRS5 was obtained from the CFHT with the Fourier Transform Spectrometer. The spectrum was measured using a Fortran program developed by the author. Four gas phase absorption components were detected in [superscript 12]CO with outflow velocities up to 38 km s[superscript-1]. Analysis of this absorption indicates gas temperatures up to 400 K with a temperature gradient possibly present. Source velocity [superscript 13]CO absorption which was also detected, demonstrates that two separate gas clouds are present along the line of sight to W3 IRS. Warm, neutral [superscript 13]CO gas has a temperature of 50 K whereas 300 AU from W3 IRS5, hot, 470 K gas is detected. Absorption due to solid phase [superscript 12]CO is interpreted as originating in the warm, neutral gas some distance from the source. A rotationally supported accretion disk, which reprocesses starlight, may explain the hot gas close to the source
Grammia eureka Ferguson & Schmidt, 2007, New Species
No full textGrammia eureka New Species (Figs. 1 h, 7) Diagnosis. Males of G. eureka resemble those of G. b o w m a n i, n. sp. (the female of bowmani unknown) but have a reduced, elliptical eye and a larger, more exposed gena; the reduced eyes suggest that both sexes are diurnal, which may help explain why so few have been collected. The longest antennal branches are shorter than those of both bowmani and nevadensis: 2–2.5 times the intersegmental length in eureka compared to 3– 3.5 and 4–4.5 for bowmani and nevadensis, respectively. The black spots of the hindwing are mainly clustered toward the outer margin as in bowmani and some forms of G. nevadensis, but the hindwing ground colour is a more orangetinted shade, not the pink to deep salmon pink of bowmani. Although somewhat faded from age, the male and female hindwings of eureka appear to be coloured alike (not as in G. nevadensis, in which female hindwing colouring is much more saturated). Also, surprisingly for a Grammia species of this group, the male genitalia appear to be distinctive (only one specimen was dissected), in that the apex of the valve is blunt and squared off, not elongate and rounded as in other members of the group (Fig. 6). Collection dates indicate a much earlier flight period than G. nevadensis, with records from April to May, compared to August through September for G. n. nevadensis. G. e u re k a and G. nevadensis are sympatric at Eureka, Utah, with numerous nevadensis specimens known from Eureka (T. Spalding; CNC, USNM) and nearby localities (D.F. Hardwick; CNC). Description. MALE. Head: Eyes reduced to little more than half the size seen in most species of Grammia, including G. nevadensis, behrii, and bowmani, and having the appearance of being directed forward. The eye reduction leaves an exposed gena, which bears a few brown scales, more in one male than the other. Upper edge of eye set well apart from base of antenna, whereas it almost touches base of antenna in species with larger eyes. Compound eye roughly equals onefourth of a sphere; that of nevadensis, bowmani, and most others of the group is onehalf a sphere or close. Antennae bipectinate with relatively short branches, the longest 2–2.5 X longer than intersegmental distance; antenna brown, the branches tending to be slightly clavate, the shaft and branches fully scaled above, setose beneath in the usual way; palpi appearing long but probably only because of their long vestiture and more conspicuous appearance relative to the reduced eye. Front and tips of palpi white at sides, otherwise dark brown or blackish. Thorax: Vertex with tuft of long, black scales; each patagium black with border of whitish vestiture along both sides; tegula black with whitish border along each side; dorsum of thorax otherwise whitish with wide middorsal black band. Thorax beneath mostly with shaggy black vestiture (with some small white patches), except for legs, which are largely white, especially the tibiae. Abdomen: Abdomen with mediumwidth black middorsal band, reddish at sides, pale ventrally except for a segmental series of vertical bars in zone between pink and pale areas. Forewing (Fig. 1 h) dorsally with an almost complete set of whitish bands, except that the basal and antemedial bands may be fragmentary as in bowmani and many specimens of nevadensis. General pattern as in other members of group except that medial band is nearly straight, as in bowmani; not as strongly convex as in nevadensis. Postmedial band curved or bent basad near costa, but not as strongly so as in most members of the nevadensis complex (bowmani differs in having this band nearly straight as in williamsii); cubital band well developed. Wing length: holotype, 16.5 mm; paratype male, 17 mm. Length to width ratio = 2.25 (n = 2). Hindwing (Fig. 1 h) dorsally orange red, not pink to salmon coloured as in bowmani, or bright red as in many nevadensis; submarginal dark spots with tendency to be concentrated as a border on outer margin much as in bowmani. Ventrally with pattern very similar to upper side, but with colour less intense. Abdomen: Male genitalia (Fig. 6) with valves relatively distinctive for this genus, with the distal part of the valve wide and spatulate, appearing squaredoff not tapered and rounded. Inner median ridge and median process of valve moderately developed; Juxta wide with broad, shallow dorsal notch; basal 1 / 4 of uncus with pronounced constriction, smoothly tapering to apex with slight constriction 2 / 3 of distance to apex. Aedeagus with strong dorsad curve at 2 / 3 distance beyond base. Vesica apparently indistinguishable from G. nevadensis, coarsely and extensively scobinate but not much more so than in related species. Largest (apical) chamber of vesica more elongate like nevadensis in comparison to the short, broad vesica of G. williamsii (Fig. 6) and G. bowmani (Fig. 8). The genitalia of only one male was examined so that the other could be kept intact for future reference and illustration, since the abdominal markings are sometimes important in Grammia. FEMALE. Head: palpus with or without pale tip. Eye reduced as in male; gena large, partly scaled; antenna somewhat laminate, appearing serrate at sides, black. Thorax: Legs black with creamcoloured markings as in male; tibiae characteristically pale outwardly (laterally), blackish inwardly (proximally). Markings of both wings much like those of male, except that basal and antemedial bands of forewing tend to be further reduced; basal band essentially absent; antemedial band wide and prominent, although broken in the middle in the Utah female, absent except for a trace at costa in the Idaho female. It should be emphasized that in most members of the nevadensis complex and other species of Grammia, the hindwings are more intensely coloured than those of the male, but G. eureka differs in having the sexes coloured alike. Length of forewing: 18 mm; lengthwidth ratio = 2.25 (n = 2). Abdomen: Generally similar to male but larger, and nearly all black ventrally. Genitalia not examined. Holotype: Male. UTAH, [Juab County], Eureka, 16 May 1909, Tom Spalding (Fig. 1 h). (illustrated in Barnes & McDunnough (1912) pl. 3, fig. 1). Paratypes: 1 male, 2 females. Male, same locality and collector as holotype, 9 May 1910, USNM Slide No. 56401; female, same locality and collector, 20 April 1910 (illustrated in Barnes & McDunnough (1912) pl. 3, fig. 8); female, IDAHO, Ada Co., Boise, Jim Manning [no date, and locality not certain see Remarks below]. All types deposited in USNM. The female dated 20 April 1910 has slightly crumpled wings as though it had been reared or perhaps collected before the wings had fully hardened. Distribution. Eastern and northern edges of the Great Basin in Utah and Idaho, insofar as known. Flight period. 20 April– 16 May. Remarks. Grammia eureka is based on three old specimens from the Barnes collection in the USNM, collected in Utah by Tom Spalding almost a century ago, and a female paratype thought to have been collected near Boise, Idaho (see below). The three Utah specimens collected in 1909 and 1910 were acquired by Barnes and McDunnough for the Barnes Collection, the largest privately held North American Lepidoptera collection of its day. Spalding was one of several field collectors from whom Barnes purchased western material or paid to collect for him, and the Barnes collection was later purchased by the U.S. Dept. of Agriculture for the National Collection. Barnes and McDunnough (1912: p. 10, pl. 3, figs. 1, 8) published photographs of the specimen here designated as holotype of G. e u re k a and the female from Utah as examples of what "is probably the true blakei.” This determination was wrong, as McDunnough must later have realized, but no one pursued the matter further. These specimens remained intact just as McDunnough (Barnes’ curator) had left them. Their specific identity has remained somewhat of a puzzle without additional specimens coming to light, with the exception of the paratype female; this specimen was received in the 1950 s by the senior author from Jim Manning, a butterfly collector of Boise, Idaho. Received as a papered specimen, it bore no data and it is merely assumed that the collection locality was at or near Boise. That region, like Eureka, Utah, is near the edge of the Great Basin, which may provide a clue to the species’ habitat.Published as part of Ferguson, Douglas C. & Schmidt, Christian, 2007, Taxonomic review of the Grammia nevadensis species group (Lepidoptera: Arctiidae) with descriptions of`two new species, pp. 39-49 in Zootaxa 1405 on pages 42-44, DOI: 10.5281/zenodo.17549
Fixation of mucus on rainbow trout (Oncorhynchus mykiss Walbaum) gills for light and electron microscopy
No full textPT: J; CR: BOLLARD JE, 1986, DIGEST DIS SCI, V31, P1338 BOYD RB, 1980, CELL TISSUE RES, V213, P361 CACECI T, 1984, J FISH BIOL, V25, P1 CORNISH J, 1987, BRIT J EXP PATHOL, V68, P369 FERGUSON HW, 1989, SYSTEMATIC PATHOLOGY, P11 GAIL DB, 1983, AM REV RESPIR DIS, V127, P366 GARLAND CD, 1979, J MICROSC, V116, P227 HANDY RD, 1991, J FISH BIOL, V38, P153 HOSSLER FE, 1986, J SUBMICR CYTOL PATH, V18, P519 HUGHES GM, 1979, J ZOOLOGY LONDON, V187, P443 HUMBERT W, 1984, J FISH BIOL, V25, P117 ICHIKAWA M, 1987, J ELECTRON MICROSC, V36, P117 KENDALL MW, 1979, J FISH RES BOARD CAN, V36, P1072 LUCHTEL DL, 1978, SCANNING ELECT MICRO, V11, P1089 OSTLAND VE, 1990, DIS AQUAT ORGAN, V9, P5 PICKERING AD, 1974, J FISH BIOL, V6, P111 PIIPER J, 1986, J EXP BIOL, V126, P499 ROZEE KR, 1982, APPL ENVIRON MICROB, V43, P1451 SIMS DE, 1991, BIOTECH HISTOCHEM, V66, P173 SPEARE DJ, 1991, J FISH DIS, V14, P21 SPEARE DJ, 1992, IN PRESS J COMP PATH SUMMERFELT RC, 1990, METHODS FISH BIOL, P213 THURSTON RJ, 1976, J ULTRASTRUCT RES, V56, P39 TURNER CR, 1990, STAIN TECHNOL, V65, P95 WHITEAR M, 1984, J FISH BIOL, V25, P317 WRIGHT PA, 1989, J COMP PHYSIOL B, V158, P627; NR: 26; TC: 14; J9: J FISH BIOL; PG: 12; GA: JY797Source type: Electronic(1
Fixation artifacts in rainbow-trout (Salmo-gairdner) gills - a morphometric evaluation
No full textPT: J; CR: ALBASSAM M, 1987, VET PATHOL, V24, P34 BENVILLE PE, 1968, TOXICOL APPL PHARM, V12, P156 CHRETIEN M, 1986, BIOL CELL, V56, P137 DAOUST PY, 1984, VET PATHOL, V21, P93 DEJOUR P, 1981, PRINCIPLES COMP RESP ELLER LL, 1975, PATHOLOGY FISHES, P305 GRIZZLE JM, 1981, T AM FISH SOC, V110, P29 HARGENS AR, 1974, COMP BIOCH PHYSL A, V48, P675 HERMAN RL, 1985, T AM FISH SOC, V114, P911 HUGHES GM, 1979, WATER RES, V13, P665 LAURENT P, 1984, FISH PHYSIOL, V10, P73 MALLATT J, 1985, CAN J FISH AQUAT SCI, V42, P630 NICHOLS DJ, 1987, COMP BIOCHEM PHYS A, V87, P703 PERRY SF, 1984, FISH PHYSL B, V10, P324 RANDALL DJ, 1981, EVOLUTION AIRBREATHI RHODIN JAG, 1964, ANAT REC, V148, P420 ROBERTS RJ, 1978, FISH PATHOL, P55 ROBIN ED, 1973, NEW ENGL J MED, V238, P292 SNEDECOR GW, 1980, STATISTICAL METHODS THOMPSON SW, 1966, SELECTED HISTOCHEMIC WALSH AH, 1975, PATHOLOGY FISHES, P515 WEST JB, 1982, PULMONARY PATHOPHYSI WOBESER G, 1975, J FISH RES BOARD CAN, V32, P2005 ZENKER WGE, 1987, COMP BIOCHEM PHYS A, V86, P423; NR: 24; TC: 21; J9: CAN J FISHERIES AQUAT SCI; PG: 6; GA: U5947Source type: Electronic(1
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