1,721,778 research outputs found
Comment on: Prevalence, outcome and management of patients with SLE and secondary antiphospholipid antibody syndrome after aPL seroconversion: reply
No full text
Monotherapy is a relevant option in rheumatoid arthritis treatment: a literature review
No full textThe latest revision of the European League Against Rheumatism (EULAR) recommendations for rheumatoid arthritis (RA) treatment maintains the indication for the combined therapy of biological disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs), namely Jak-inhibitors as tofacitinib and baricitinib, with conventional synthetic DMARDs (csDMARDs). Moreover, the use of bDMARDs and tsDMARDs should be restricted to patients who failed to achieve an adequate response to one or more csDMARDs, in accordance with the current evidence showing the superiority of combination therapy over monotherapy. In patients who cannot use csDMARDs as comedication, IL-6 inhibitors and tsDMARDs should be preferred to other bDMARDs because they are apparently more effective as monotherapy. Registry and real-world data demonstrate that monotherapy is far more commonly used than expected based on treatment recommendations, currently being about 30% of patients with RA on bDMARD monotherapy. We review here the literature on most commonly used DMARDs in monotherapy for RA. Our review points at an increasing evidence of the potential of some bDMARDs and tsDMARDs in monotherapy, which may become a considerable and realistic option in RA patients
Fibromialgia-cap. 9 Reumatismi extra-articolari
No full textEpidemiologia, Eziopatogenesi, Quadro clinico, Manifestazioni extra-muscolo-scheletriche, Nuovi criteri per la diagnosi,
Esami bioumorali, Esami strumentali, Diagnosi, Diagnosi differenziale, Prognosi, Clinimetria, Terapi
PRINCIPALI SINTOMI E SEGNI DELL’APPARATO LOCOMOTORE- Cap. 2 Basi per lo studio delle malattie reumatiche
No full textESAME OBIETTIVO DELL’APPARATO LOCOMOTORE-Cap. 2 Basi per lo studio delle malattie reumatiche
No full textPalpazione , Valutazione del movimento, Manovre semeiologiche particolari, Esame obiettivo di specifiche
Articolazioni, Rachide cervicale, Rachide dorsale, Rachide lombosacrale, Articolazioni sacroiliache, Anc
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