1,720,997 research outputs found
A note on Lang's conjecture for quotients of bounded domains
Full text linkIt was conjectured by Lang that a complex projective manifold is Kobayashi hyperbolic if and only if it is of general type together with all of its subvarieties. We verify this conjecture for projective manifolds whose universal cover carries a bounded, strictly plurisubharmonic function. This includes in particular compact free quotients of bounded domains
Glycocomposition of the apocrine interdigital gland secretions in the fallow deer (Dama dama)
Full text linkThe secretions of the tubular interdigital glands were investigated by conventional (Periodic-Acid Schiff,
Alcian-Blue at different pH, Low Iron Diamine and High Iron Diamine) and lectin (Con-A, UEA-I, LTA,
WGA, GSA-II, GSA-IB4, SBA, PNA, ECA, DBA, MAL-II and SNA) histochemical methods in adult males
and females of different age of fallow deer during the breeding season. Sialidase digestion and deacetylation
pre-treatment were also employed in conjunction with lectin histochemistry.
The glandular epithelium consisted of a single layer of low columnar cells with typical apical protrusions.
No substantial differences of the above histochemical staining in relation to sex and age were
observed. Conventional histochemical staining revealed that the interdigital glands secreted neutral glycoproteins
whereas acidic glycocomponents did not seem to be present. Lectin histochemical technique
allowed us to disclose a great heterogeneity of glycoproteins with N- and O-linked oligosaccharides containing
alpha-D-Man/alpha-D-Glc, GlcNAc, alpha-Fuc, terminal beta-D-Gal-(1-3)-D-GalNAc, -D-Gal-(1-4)-D-GlcNAc, alpha-Gal
and beta-GalNAc residues. beta-GalNAc and disaccharide beta-D-Gal-(1-3)-D-GalNAc were also found as subterminal
to sialyl moieties. The lack of sexual and age-related differences in the glucidic content of the glandular
secretions seems to indicate that the glycoderivatives may play only an accessory role in the
production of odoriferous signals in fallow deer
On subvarieties of singular quotients of bounded domains
Full text linkLet (Formula presented.) be a quotient of a bounded domain in (Formula presented.). Under suitable assumptions, we prove that every subvariety of (Formula presented.) not included in the branch locus of the quotient map is of log-general type in some orbifold sense. This generalizes a recent result by Boucksom and Diverio, which treated the case of compact, étale quotients. Finally, in the case where (Formula presented.) is compact, we give a sufficient condition under which there exists a proper analytic subset of (Formula presented.) containing all entire curves and all subvarieties not of general type (meant this time in in the usual sense as opposed to the orbifold sense)
Weakly Kähler hyperbolic manifolds and the Green–Griffiths–Lang conjecture
Full text linkWe introduce the notion of weakly Kähler hyperbolic manifold which generalizes that of Kähler hyperbolic manifold given in the early 1990s by M. Gromov, and establish its basic features. We then investigate its spectral properties and show a spectral gap result (on a suitable modification). As applications, we prove that weakly Kähler hyperbolic manifolds are of general type and we study the geometry of their subvarieties and entire curves, verifying – among other things – various aspects of the Lang and the Green–Griffiths conjectures for this class of manifolds
The effect of training and competition on the endocrine-metabolic response to stress in trotters.
No full textSince iti is possible that additional stressors may exacerbate the agonistic related stress response in athletic horses, we investigated and compared the endocrine-metabolic changes elicited by training and sporting competition in trotters. A group of 8 trotters were randomly subjected to two different treatments: a standard training and a sporting competition. Higher plasma beta-endorphin , cortisol, PCV, total proteins, LDH and Ca concentration were recorded after competition (P<0.001). Within 12o minall parameters returned within their normal reest values
Variations in the lectin-binding on the zona pellucida during oocyte growth in some wild ungulates
Full text linkThe aim of the present study was to examine the glycoconjugate modifications occurring in the zona pellucida during oocyte growth in fallow, red and roe deer using a battery of lectins combined with sialidase digestion and chemical treatments. This histochemical approach allowed us to sequence the oligosaccharidic side chains of the zona pellucida glycoproteins in these wild ungulates. The most effective lectins in the zona pellucida of these species were SBA, PNA, RCA-I GSA-IB4, and WGA, indicating the presence of beta-D-N-Acetylgalactosamine, beta-D-Galactose, alpha-D-Galactose and N-Acetylglucosamine residues. Additionally, sialic acid moieties were demonstrated. We also observed differences in the glycosidic residue content and in their spatial distribution, depending on the species and stage of follicle development
Histochemical detection of the lectin-binding carbohydrates in the zona pellucida during oocyte growth in the wild boar (Sus scrofa scrofa)
Full text linkThe changes that occur in the carbohydrate composition of zona pellucida glycoproteins during oocyte maturation in the wild-boar were studied using periodic-acid Schiff (PAS), High Iron Diamine (HID) and Low Iron Diamine (LID). Lectin staining was performed with a panel of 11 HRP-lectin conjugates combined with neuraminidase digestion and chemical treatments. There were few internal glucidic residues, such as N-acetylglucosamine, in the wild boar zona pellucida but there were many subterminal beta-N-acetylgalactosamine, alpha- and beta-galactose determinants masked by sialic acid. In addition, beta-N-acetylgalactosamine, beta-galactose-(1-3)-N-acetylgalactosamine and beta-galactose-(1-4)-N-acetylglucosamine were detected in the sulphated form in the terminal and/or subterminal position. Some differences in the lectin reactive sites occurred in the zona pellucida, depending on the stage of oocyte maturatio
Quasi-negative holomorphic sectional curvature and positivity of the canonical bundle
Full text linkWe show that if a compact complex manifold admits a Kähler metric whose holomorphic sectional curvature is everywhere non-positive and strictly negative in at least one point, then its canonical bundle is positive. This answers in the affirmative to a question first asked by S.-T. Yau
Partial analytic validation of determination of cortisol in dog hair using a commercial EIA kit
Full text linkThe quantification of cortisol in hair samples is a relatively recent method that has been increasingly used for the evaluation of long-term cortisol secretion and chronic stress levels, in both humans and non-human animals. The use of hair presents many advantages in relation to the use of other biological matrices, e.g. a very low invasiveness of the sample collection. Besides, cortisol analysis in hair samples provides measurements over a long period of time, which can be used as a chronic stress indicator. Nevertheless, the physiology of cortisol in hair and the evaluation of reliable methods for its quantification in hair samples need to be further investigated. The aim of this study was to perform a partial analytical validation for the quantification of cortisol in domestic dog hair samples using a commercially available high sensitivity salivary cortisol enzyme immunoassay kit. Results on both precision and linearity tests were overall favorable, supporting that the kit can be used to reliably measure hair cortisol concentrations in dogs
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