196,109 research outputs found
Epidemiology and evolution of the diagnostic classification of factitious disorders in DSM-5
No full textIvano Caselli, Nicola Poloni, Marta Ielmini, Marcello Diurni, Camilla Callegari Department of Medicine and Surgery, Section of Psychiatry, University of Insubria, Varese, Italy Abstract: A systematic search for all case reports and case series of adult patients with factitious disorders (FD) in the databases MEDLINE, Scopus, and PsycINFO was conducted. FD is a psychiatric disorder in which sufferers intentionally fabricate physical or psychological symptoms in order to assume the role of a patient, without any obvious gain. The clinical and demographic profile of patients with FD has not been sufficiently clear. Thus, the aims of this study were to outline a demographic and clinical profile of a large sample of patients with FD and to study the evolution of the position of FD in the Diagnostic and Statistical Manual of Mental Disorders. One thousand six hundred thirty-six records were obtained based on key search terms, after exclusion of duplicate records. Five hundred seventy-seven articles were identified as potentially eligible for the study, of which 314 studies were retrieved for full-text review. These studies included 514 cases. Variables extracted included age, gender, reported occupation, comorbid psychopathology, clinical presentation, and factors leading to the diagnosis of FD. In the sample, 65.4% of patients were females. Mean age at presentation was 33.5 years. A health care profession was reported most frequently (n=113). Patients were most likely to present in psychiatry, neurology, emergency, and internal medicine departments. The broad survey of sociodemographic profile of the sample has highlighted some important points for early diagnosis and early psychiatric treatment. The study showed that the patients did not meet Diagnostic and Statistical Manual of Mental Disorders-5 diagnostic criteria in 11.3% of cases. Keywords: fabricated illness, factitious disorder, medically unexplained symptoms, Munchausen syndrom
Applicazione di una metodica di valutazione nei Centri diurni della regione Toscana: presentazione dei risultati della ricerca
No full textIl Coordinamento Toscano dei Centri Diurni ha condotto uno studio su 20 centri diurni rilevando le caratteristiche socio-anagrafiche e cliniche di 330 utenti ed utilizzando i seguenti strumenti standardizzati per la valutazione di esito: 1) Health of the Nation Outcome Scales (HoNOS- Roma); 2) General Satisfaction Questionnaire for psychiatric inpatients (GSQ-8); 3) Questionario dei problemi familiari (QPF). Nel presente studio descriviamo le caratteristiche degli utenti che afferiscono ai centri diurni e presentiamo i dati di follow-up condotti a 6 e 12 mesi, considerando le modificazioni relative ai sintomi psicopatologici e le modificazioni del funzionamento sociale
Applicazione di una metodica di valutazione nei centri diurni della regione Toscana: presentazione dei risultati della ricerca
No full textIl Coordinamento Toscano dei Centri Diurni ha condotto uno studio su 20 centri diurni rilevando le caratteristiche socio-anagrafiche e cliniche di 330 utenti ed utilizzando i seguenti strumenti standardizzati per la valutazione di esito: 1) Health of the Nation Outcome Scales (HoNOS- Roma); 2) General Satisfaction Questionnaire for psychiatric inpatients (GSQ-8); 3) Questionario dei problemi familiari (QPF). Nel presente studio descriviamo le caratteristiche degli utenti che afferiscono ai centri diurni e presentiamo i dati di follow-up condotti a 6 e 12 mesi, considerando le modificazioni relative ai sintomi psicopatologici e le modificazioni del funzionamento social
Prime liste faunistiche di Lepidotteri diurni in aree protette italiane
No full textNell’ambito del progetto Life+ 2008, Validation of risk management tools for genetically modified plants in protected and sensitive areas in Italy (MAN-GMP-ITA), sono stati condotti studi di caratterizzazione dell’entomofauna di alcune aree protette in Italia, da marzo a settembre di due anni consecutivi (2011-2012). Tali studi hanno condotto alla redazione di liste faunistiche di Lepidotteri diurni, Lepidotteri notturni e Coccinellidi per ciascun sito. I due gruppi di specie sono stati scelti in considerazione del loro possibile ruolo come specie “non-target” in studi di impatto ambientale.
Le aree oggetto di studio sono state scelte in modo da essere rappresentative di diverse aree bio-geografiche in Italia (2 aree al nord, 1 al centro e 3 al sud):
o IT4050001 - SCI Gessi bolognesi e Calanchi dell'Abbadessa (Bologna)
o IT4050024 - SCI/SPZ Biotopi e ripristini ambientali di Bentivoglio, San Pietro in Casale, Malalbergo e Baricella (Bologna)
o IT6030015 - SCI Macchia di Sant'Angelo Romano (Roma)
o IT9220090 - SCI Costa Ionica - Foce Bradano (Metaponto – MT / Ginosa – TA)
o ITA020006 - SCI Capo Gallo (Palermo)
o ITA020023 - SCI Raffo Rosso, Monte Cuccio e Vallone Sagana (Palermo)
Lo scopo del presente lavoro è stato quello di: 1) costruire una lista faunistica per questi particolari siti in cui non esisteva (eccetto per un unico studio sui Lepidotteri diurni nell’area SIC IT4050024) nessun riferimento bibliografico e 2) comparare la lepidotterofauna diurna rilevata nelle diverse aree e individuare specie potenzialmente esposte, quali bioindicatori specifici nelle diverse aree
Effetti metabolici dei farmaci antipsicotici di seconda generazione in pazienti dru-naive: uno studio preliminare
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Injection of colorectal cancer cells in mesenteric and antimesenteric sides of the colon results in different patterns of metastatic diffusion: An experimental study in rats
No full textAbstract Background This experimental study was designed to investigate the differences in pattern of local growth and diffusion of colorectal cancer cells injected into either mesenteric (M) or antimesenteric (AM) sides of the colon. Methods A total of 1 × 106 colonic adenocarcinoma cells (line DHD/K12-TRb) were injected into the cecal wall of BDIX syngeneic male rats at an M or AM site of the colon. At six weeks after injection, all animals were sacrificed and the presence or absence of tumor in the cecum as well as regional metastasis and peritoneal carcinomatosis were determined. Results Six weeks after injection, macroscopic tumor growth was observed in 27/37 (72%) animals in group M and 21/32 (65%) in group AM (P = 0.98). In group AM, diffuse peritoneal carcinomatosis was present in 19/21 rats (90.4%) versus 3/27 rats (11%) in group M; this difference was statistically significant (P = 0.025). Regional mesenteric lymph nodes were the only location in which tumor was detected in 23/27 rats (85%) in group M versus 2/21 (9.5%) in group AM; this difference too was statistically significant (P = 0.031) Conclusion The patterns of diffusion of tumors implanted in mesenteric and antimesenteric sites of the colon appear to be different, although the reason for this is not clear.</p
Injection of colorectal cancer cells in mesenteric and antimesenteric sides of the colon results in different patterns of metastatic diffusion: an experimental study in rats
No full textThis experimental study was designed to investigate the differences in pattern of local growth and diffusion of colorectal cancer cells injected into either mesenteric (M) or antimesenteric (AM) sides of the colon. A total of 1 x 10(6) colonic adenocarcinoma cells (line DHD/K12-TRb) were injected into the cecal wall of BDIX syngeneic male rats at an M or AM site of the colon. At six weeks after injection, all animals were sacrificed and the presence or absence of tumor in the cecum as well as regional metastasis and peritoneal carcinomatosis were determined. Six weeks after injection, macroscopic tumor growth was observed in 27/37 (72%) animals in group M and 21/32 (65%) in group AM (P = 0.98). In group AM, diffuse peritoneal carcinomatosis was present in 19/21 rats (90.4%) versus 3/27 rats (11%) in group M; this difference was statistically significant (P = 0.025). Regional mesenteric lymph nodes were the only location in which tumor was detected in 23/27 rats (85%) in group M versus 2/21 (9.5%) in group AM; this difference too was statistically significant (P = 0.031) The patterns of diffusion of tumors implanted in mesenteric and antimesenteric sites of the colon appear to be different, although the reason for this is not clear
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