100,361 research outputs found
Qualcuno volò dal nido familiare: convivenza o matrimonio? Spagna e Portogallo a confronto
No full textIn Spagna e Portogallo il matrimonio continua ad essere la forma prevalente di unione (88% di
entrata in matrimonio per la Spagna e 95% per il Portogallo); anche se le generazioni di donne più
giovani manifestano una maggior propensione alla convivenza rispetto alle coorti precedenti. I nati tra il 1978 e il 1985 presentano una maggiore tendenza a convivere
rispetto a coloro che sono nati nella prima metà del XX secolo, più in Spagna che in Portogallo
(23,9% vs 20,2%).Si noti che la convivenza, confrontata con il matrimonio quale prima unione,
differisce significativamente tra i due Paesi, con una più ampia e anticipata diffusione in Spagna. La fonte di dati utilizzata permette di
confrontare le differenze tra convivenza e matrimonio attraverso la loro relazione con altri eventi del
corso di vita quali: l’età media all’unione, l’attività lavorativa, l’emancipazione dal nucleo familiare e
la presenza di figli
Nonaffine correlations in random elastic media
No full textDiDonna, B.A.; Lubensky, T.C.. (2005). Nonaffine correlations in random elastic media. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/4156
Topical anesthesia for hysteroscopy in postmenopausal women
No full textAbstract
STUDY OBJECTIVE:
To evaluate the efficacy and safety of topical anesthesia in reducing pain and the frequency of vasovagal reactions during diagnostic hysteroscopy with endometrial biopsy in postmenopausal women.
DESIGN:
Randomized, placebo-controlled, double-blind study.
SETTING:
A university hospital.
PATIENTS:
Forty-two postmenopausal women undergoing diagnostic hysteroscopy and endometrial biopsy.
INTERVENTIONS:
Two milliliters of 2% mepivacaine or saline solution was injected transcervically into the uterine cavity before performing the procedures.
MEASUREMENTS AND MAIN RESULTS:
Pain was evaluated on a visual analog scale, and heart rate and blood pressure were monitored continuously. Anesthesia reduced the pain experienced at hysteroscopy and endometrial biopsy, but not significantly. The frequency of vasovagal reactions was significantly lower in the anesthetized group.
CONCLUSIONS:
Topical anesthesia effectively prevents the occurrence of vasovagal reactions in postmenopausal women undergoing hysteroscopy and endometrial biopsy
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Topical anesthesia in diagnostic hysteroscopy and endometrial biopsy in post-menopausal women:a randomized placebo-controlled double-blind study
No full textOBJECTIVE:
To evaluate the efficacy and safety of topical anaesthesia in reducing pain and incidence of vasovagal reactions during diagnostic hysteroscopy with endometrial biopsy in postmenopausal women.
DESIGN:
Randomised placebo-controlled double-blind study.
SETTING:
University hospital.
PARTICIPANTS:
Eighty postmenopausal women undergoing diagnostic hysteroscopy and endometrial biopsy.
INTERVENTIONS:
Two millilitres of 2% mepivacaine or saline solution were injected transcervically into the uterine cavity before performing the procedures.
MAIN OUTCOME MEASURES:
Evaluation of pain reduction on a visual analogue scale and continuous monitoring of heart rate and blood pressure.
RESULTS:
The use of the anaesthetic significantly reduced the pain experienced at hysteroscopy and endometrial biopsy. The occurrence of vasovagal reactions was significantly lower in the anaesthetised group.
CONCLUSIONS:
Topical anaesthesia attenuated pain and effectively prevented the occurrence of vasovagal reactions during hysteroscopy and endometrial biopsy in postmenopausal women
Topical anaesthesia for diagnostic hysteroscopy and endometrial biopsy in postmenopausal women: a randomised placebo-controlled double-blind study
No full textParacervical anesthesia for hysteroscopy and endometrial biopsy in postmenopausal women. A randomized, double-blind, placebo-controlled study
No full textDifferent plasma levels of nitric oxide in arterial and venous blood in postmenopausal women
No full text
Characterization of four new monoclonal antibodies against the distal N-terminal region of PrPc
No full textPrion diseases are a group of fatal neurodegenerative disorders that affect humans and animals. They are characterized by the accumulation in the central nervous system of a pathological form of the host-encoded prion protein (PrPC). The prion protein is a membrane glycoprotein that consists of two domains: a globular, structured C-terminus and an unstructured N-terminus. The N-terminal part of the protein is involved in different functions in both health and disease. In the present work we discuss the production and biochemical characterization of a panel of four monoclonal antibodies (mAbs) against the distal N-terminus of PrPC using a well-established methodology based on the immunization of Prnp0/0 mice. Additionally, we show their ability to block prion (PrPSc) replication at nanomolar concentrations in a cell culture model of prion infection. These mAbs represent a promising tool for prion diagnostics and for studying the physiological role of the N-terminal domain of PrPC
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