1,721,113 research outputs found
Topical immunotherapy with squaric acid dibutylester: unusual hair pigmentary changes in two cases of alopecia areata.
No full textTopical immunotherapy with contact sensitizers: a model to study the natural history of delayed hypersensitivity
No full textSo-called ‘topical immunotherapy’ (TI) is a well-established treatment modality based on the use of potent contact sensitizers, such as squaric acid dibutylester (SADBE), that are not found in the general or occupational environment of man, and do not induce cross-sensitization to other substances. Thus, unlike patients with sensitivity to other more or less commonplace allergens, subjects submitted to this treatment modality might provide useful data for the study of the natural course of contact sensitivity. On the basis of these premises, we have retrospectively reviewed 40 patients who had consecutively received TI with SADBE for severe alopecia areata and viral warts in the period 1993–2001, and returned to visit after a 1–7-year period since the last therapeutic challenge with the sensitizer. The chronological profile of loss of contact sensitization of this case cohort has been evaluated and compared to that of other series available in the literature. Provided more standardized TI application procedures are established, aim-oriented studies of the outcome of this treatment modality may bring useful data to be employed in construction of predictive models of decay of contact sensitization under conditions of antigen avoidance
Seborrhoeic dermatitis in the elderly: inferences on the possible role of disability and loss of self-sufficiency
No full textSeborrhoeic dermatitis in the elderly: inferences on the possible role of disability and loss of self-sufficiency
No full textDermatite allergica da contatto all'acido sulfonico fenil benzimidazolico e all'ottil dimetil PABA
No full textSurvival of substructure within dark matter haloes
No full textUsing high-resolution cosmological N-body simulations, we investigate the survival of dark matter satellites falling into larger haloes. Satellites preserve their identity for some time after merging. We compute their loss of mass, energy and angular momentum as they are dissolved by dynamical friction, tidal forces and collisions with other satellites. We also analyse the evolution of their internal structure. Satellites with less than a few per cent of the mass of the main halo may survive for several billion years, whereas larger satellites rapidly sink into the centre of the main halo potential well and lose their identity. Penetrating encounters between satellites are frequent and may lead to significant mass loss and disruption. Only a minor fraction of cluster mass (10-15 per cent on average) is bound to substructure at most redshifts of interest. We discuss the application of these results to the survival and extent of dark matter haloes associated with galaxies in clusters, and to their interactions. We find that a minor fraction of galaxy-size dark matter haloes are disrupted by redshift z=0. The fraction of satellites undergoing close encounters is similar to the observed fraction of interacting or merging galaxies in clusters at moderate redshift
Deep spectroscopic luminosity function of Abell 85 : no evidence for a steep upturn of the faint-end slope
Full text linkIA, AD and ALS acknowledge partial support from the INFN grant InDark and from the grant Progetti di Ateneo TO Call 2012 0011 ‘Marco Polo’ of the University of Torino.We present a new deep determination of the spectroscopic luminosity function (LF) within the virial radius of the nearby and massive Abell 85 (A85) cluster down to the dwarf regime (M* + 6) using Very Large Telescope/Visible Multi-Object Spectrograph (VLT/VIMOS) spectra for ∼2000 galaxies with mr ≤ 21 mag and 〈μe,r〉 ≤ 24 mag arcsec−2. The resulting LF from 438 cluster members is best modelled by a double Schechter function due to the presence of a statistically significant upturn at the faint end. The amplitude of this upturn (αf ~ -1.58+0.19-0.15), however, is much smaller than that of the Sloan Digital Sky Survey (SDSS) composite photometric cluster LF by Popesso et al., αf ∼ −2. The faint-end slope of the LF in A85 is consistent, within the uncertainties, with that of the field. The red galaxy population dominates the LF at low luminosities, and is the main factor responsible for the upturn. The fact that the slopes of the spectroscopic LFs in the field and in a cluster as massive as A85 are similar suggests that the cluster environment does not play a major role in determining the abundance of low-mass galaxies.Peer reviewe
A sub-resolution multiphase interstellar medium model of star formation and SNe energy feedback
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