1,721,041 research outputs found
Psychiatric disorders in burning mouth syndrome
No full textObjectives. The aim of this observational study was to evaluate the prevalence of psychiatric symptoms in the population
of patients with Burning Mouth Syndrome (BMS).
Methods. 25 patients (mean age 61 y.o.), 23 females (92%) and 2 males (8%), with BMS, of the Dental Clinic of the
Second University of Naples, underwent a psychiatric evaluation, with clinical interview and the feeding of five psychometric
scales: Visual Analogue Scale (VAS), Hamilton Rating Scale for Depression (HRSD), State-Trait Anxiety
Inventory (STAI 1-2), Distress Thermometer (DT) and Brief Fatigue Inventory (BFI). Pearson’s analysis (r) was performed
for variables distress, pain (VAS score), state and trait anxiety and depressive symptoms on the HAM-D. Distress
was tested in a linear regression model with stepwise method, with independent variables VAS, STAI-state and
STAI-trait.
Results. 48% of the sample presented a VAS score of severe type, 32% moderate type, and 20% mild type; 56%
had depressive symptoms; 91% had a score above the cut-off for state anxiety and 83% for trait anxiety; 68% presented
Fatigue (70% severe, 30% mild to moderate); 96% presented Distress (64% severe, 32% moderate type).
Pearson’s analysis (r) showed that variable Distress correlates with VAS score (r = 0.723, p = 0.0001), with state
anxiety (r = 0.584, p = 0.01) and trait anxiety (r = 0.637, p = 0.001). Results showed that distress is influenced by
pain (VAS) (p = 0.0001) and trait anxiety (STAI Y-2) (p = 0.01).
Conclusions. Significant correlation between the intensity of the pain (burning), the presence of anxious trait and
the presence of Distress have been found; the anxious trait and a greater intensity of burning are predictors for the
development of Distress. These results show the influence of psychiatric disorders in the pathophysiology of BMS so
clinicians may suggest a psychiatric consultation to improve treatment efficacy
ULTRASOUND IMAGING OF ORAL FIBROMA: A CASE REPORT
No full textOral mucosa is constantly under the influence of various internal and external stimuli, therefore it is interested by a range of developmental disorders, irritation, inflammation, and neoplastic conditions. Traumatic fibroma is one of these lesions. The aim of this work is to obtain an ultrasound characterization of a lip fibroma with a high frequency probe (8-18 MHz) as feasibility and experimental model of this non-invasive technique in the oral mucosa compared with its histo-pathological section. Ultrasound characterization of a fibroma in a 50-year-old patient in the right retro commissural area of mucosa was performed. The ultrasound images were compared with its histological image. Fibroma is a traumatic lesion clinically recognizable and with a complex and well-defined histopathology structure. Although further investigations are necessary to determine the potential of ultrasonographic images as an aid in the diagnosis of oral lesions, this case report might be a model for ultrasound imaging compared with its histological section.Oral mucosa is constantly under the influence of various internal and external stimuli, therefore it is interested by a range of developmental disorders, irritation, inflammation, and neoplastic conditions. Traumatic fibroma is one of these lesions. The aim of this work is to obtain an ultrasound characterization of a lip fibroma with a high frequency probe (8-18 MHz) as feasibility and experimental model of this non-invasive technique in the oral mucosa compared with its histo-pathological section. Ultrasound characterization of a fibroma in a 50-year-old patient in the right retro commissural area of mucosa was performed. The ultrasound images were compared with its histological image. Fibroma is a traumatic lesion clinically recognizable and with a complex and well-defined histopathology structure. Although further investigations are necessary to determine the potential of ultrasonographic images as an aid in the diagnosis of oral lesions, this case report might be a model for ultrasound imaging compared with its histological section
Effetto dell’integrazione dietetica di elevate dosi di vitamine C ed E sulle caratteristiche qualitative del seme fresco e conservato di coniglio.
No full textDuring a four month period, 48 hybrid bucks, allotted to four experimental groups, were fed ad lib diets with different supplementation of vitamins C and E (BD: basal diet, 40 ppm of vitamin E; E200 and E400: BD plus 200 and 400 ppm of vitamin E respectively; E200+C: BD plus 200 ppm of vitamin E and 1,000 ppm of vitamin C). Pooled semen samples obtained from 4 bucks per each group, after dilution in Tris-Buffer (20% yolk egg), were measured by CASA (Computer Aided Sperm Analysis) as fresh or stored at 5 deg C for 48 h. The results indicated that vitamin supplementation did not affect either the fresh and stored semen quality, with the exception of amplitude of lateral head displacement (ALH), which showed higher values in rabbits receiving high levels of vitamin
Surgical treatment of oral cavity nodular fasciitis
No full textBackground: Nodular fascitiis is a myofibroblastic neoplasm of the soft tissue that rarely affects oral cavity. With a broad pattern of presentation, sometimes Nodular Fascitiis can have a rapid growth and appear highly cellular with local aggressiveness on biopsies, thus simulating a sarcoma. The aim of this paper is to present a case of troublesome diagnosis of nodular fascitiis mimicking a Malignant Fibrous Histiocytoma, with the purpose of alert clinicians and pathologists on the difficulties that can be met in the differential diagnosis between these 2 lesions. A 42-year-old male presented an exophytic lesion on the cheek. After the excisional biopsy, histological and immunohistochemical evaluations revealed a picture of doubtful significance. With a careful analysis, the diagnosis of nodular fasciitis was made and the patient was not further treated. At a 3-year follow-up, no recurrence was found. Differential diagnosis within myofibroblastic neoplasm can be a real challenge for both Clinicians and Pathologist. A coordinated team-work is mandatory to avoid clinical malpractice and unnecessarily aggressive treatment
Real time in vivo confocal microscopic analysis of the enamel remineralization by casein phosphopeptide-amorphous calcium phosphate (CPP-ACP): A clinical proof-of-concept study
No full textEnamel defects (EDs) are qualitative and/or quantitative disturbances of the dental surface. To date, the responsiveness to remineralizing treatments has been studied ex vivo, on dental sections from extracted teeth. The present research aims to establish if in vivo reflectance confocal laser scanning microscopy is able to visualize the changes in the enamel architecture on living teeth, before, during and after remineralizing treatments by casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). As proof-of-concept study, 17 consecutive children affected by EDs were enrolled and 38 EDs were considered. A CPP-ACP mousse was applied twice a week for 6 weeks and clinical and microscopic images were collected before, during and after the treatment for evaluating the changes occurred. For in vivo microscopic imaging, a reflectance confocal laser scanning microscope (RCM) for in vivo use was adopted. In this study RCM was proven to be able to visualize in vivo and at microscopic resolution the changes occurred during the remineralizing processes without needing for dental extractions and histopathological procedures. This in vivo RCM capability could encourage its clinical application in monitoring responsiveness to enamel therapies
Topical toluidine blue-mediated photodynamic therapy for the treatment of oral lichen planus
No full textPhotodynamic Therapy (PDT) is a minimally invasive approach that has shown promising results in management of oral, head and neck lesions. PDT can be used alone or in combination with other conventional treatments (surgery, chemotherapy, radiotherapy). Oral Lichen Planus (OLP) is a mucosal and cutaneous chronic disease characterized by an autoimmune insult of basal keratinocytes. We aim to evaluate the feasibility of topical toluidine blue-mediated PDT for the treatment of oral cavity multifocal homogeneous white lesions by oral lichen planus without dysplastic features
High-Definition Ultrasound Characterization of Squamous Carcinoma of the Tongue: A Descriptive Observational Study
Full text linkHigh-definition ultrasonography is a diagnostic tool that uses sound echoes to produce images of tissues and organs. In the head and neck region, ultrasounds have been used to diagnose different types of lesions. The intraoral approach was shown to be a real-time, non-invasive way to characterize oral lesions. The tongue is the most often examined region because of its accessibility. This observational study aimed to describe the qualitative characteristics of tongue squamous cell carcinoma images obtained with high-definition intraoral ultrasound by comparing them with the corresponding histopathological sample. Twenty patients were enrolled in this study. The scans of the lesions were carried out with an 18 MHz linear ultrasound probe following the long axis of the lesion. For each lesion, five frames were selected, on which descriptive analysis was performed. A histological sample was taken and then compared to the ultrasonographic acquisition. The so-nographic appearance of the tissue layers has a good correlation between ultrasound and histolog-ical morphology, and it was easy to distinguish the tumor from the homogenous composition of the tongue tissues. Furthermore, a correlation between the structure by section and pattern of tumor margin features by ultrasound was obtained. Intraoral ultrasonography appears to be a promising technique in the non-invasive characterization of tongue squamous cell carcinoma. Further studies will be needed to improve the technique in terms of ergonomics and repeatability
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