1,720,963 research outputs found
Thyroid and thyrotropin functions in subjects with pituitary nanism treated with growth hormone
No full textValutazione della secrezione dell'ormone della crescita durante 24 ore nella sindrome di Turner
No full textEffetto di un antagonista colinergico sulla secrezione di GH in eta' pediatrica. Dati preliminari
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The correlation between blood concentrations of somatomedin C and the auxological characteristics in short-stature subjects
No full textGHRH-test in short children with "non classic" GH deficiency. A comparison with "classic" GH deficiency and short normal stature.
No full textn this study GHRH-test has been performed (2 micrograms/Kg of an iv bolus of GHRH 1-44) sampling for GH measurement every 15 min over 2 hours in three groups of short children. Group 1 consisted of 10 subjects with classic GH deficiency (CGHD): GH response less than 10 ng/ml to two conventional tests and 24-h mean GH concentration (MGHC) less than 3 ng/ml; group 2 consisted of 16 subjects with non-classic GH deficiency (NCGHD): response greater than 10 ng/ml to at least one conventional test and MGHC less than 3 ng/ml; group 3 consisted of 18 subjects with short normal stature: GH response greater than 10 ng/ml to at least one conventional test and MGHC greater than 3 ng/ml. GH peak and area under the curve (AUC) values were significantly lower in group 1 than groups 2 and 3 and in group 2 than group 3. GH peak and AUC values statistically correlated with height, height velocity, bone age/chronological age ratio and MGHC. Six children in group 1, 14 children in group 2 and all 18 children in group 3 showed after GHRH a GH peak greater than 10 ng/ml and were considered as 'responders'. Considering only the responders, GH peak and AUC values were significantly lower in group 1 than groups 2 and 3 and in group 2 than group 3. In conclusion, our data have shown that 87% of children with NCGHD responded to a single bolus of GHRH with an increase in GH levels greater than 10 ng/ml and that their responses were intermediate compared to those of CGHD and short normal subjects
Valutazione della secrezione notturna dell'ormone della crescita. Rapporto con la secrezione durante le 24 ore.
No full textImpiego del test dell’ipoglicemia insulino-indotta nella valutazione della secrezione somatotropinica nei bambini con deficit staturale. considerazioni su 325 casi
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