1,721,045 research outputs found
["STRESSEN" in the treatment of psycho-physical stress and hyperhomocysteinemia in patients with migraine without aura].
No full textA previous clinical trial evidenced, in patients affected by migraine without aura, that treatment with medicinal product STRESSEN determined a reduction of homocysteinemia and an improved general state of health, also if the protocol had not provided for the latter evaluation. The aim of this study is to confirm, in a similar population, the efficacy of STRESSEN on hyperhomocysteinemia and to control the psycho-physical state of the patients by means of specific parameters. 20 hyperhomocysteinemic (> 15 micromol/ 1) patients suffering from psycho-physical stress and migraine without aura were enrolled. The efficacy of a 30 days treatment with STRESSEN was evaluated through dosage of this amino acid and through a questionnaire on the general state of health. Homocysteinemia was reduced of 52.1% (P < 0.001) and the score representing the general state of health decreased from 1.63 +/- 0.38 to 0.78 +/- 0.12 (P < 0.001). This study supported the effectiveness of STRESSEN treatment to restore physiological profile of homocysteinemia and to improve the psycho-physical conditions, usually altered by stress for which the drug is already indicated
[Comparison of treatment with STRESSEN and arginine glutamate on homocysteine blood levels].
No full textElevated plasma concentrations of homocysteine may occur because of impaired metabolism of this amino acid as a result of genetic factors or can be attributed to inadeguate blood levels of folate and vitamin B12. Recent studies demonstrated that STRESSEN decreases homocysteinemia more than the above mentioned vitamins do, as reported in literature; this behaviour could be due to the presence in the drug of arginine glutamate, whose specific activity, in comparison with STRESSEN, is here evaluated. The trial was carried out on 20 patients with hyperhomocysteinemia (> 15 micromol/l) and affected by migraine without aura; 10 subjects have received STRESSEN and 10 arginine glutamate. After 30 days of treatment, homocysteinemia was evaluated. Reduction of blood concentration of this amino acid was 56.3% (P < 0.001) after STRESSEN therapy and 27.0% (P < 0.001) after arginine glutamate. Obtained results show, for the first time, the efficacy of arginine glutamate on homocysteinemia and strengthen the hypotesis that STRESSEN activity is due to all its components, including arginine glutamate that itself acts on this parameter
Segreteria Editoriale della Rivista Hemicrania, organo ufficiale della Società Italiana per lo Studio delle Cefalee dal 1992 al 1994.
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Cluster headache in a patient with Hodgkin's lymphoma in the course of roentgen- and chemotherapy [CEFALEA A GRAPPOLO INSORTA IN SOGGETTO AFFETTO DA MORBO DI HODGKIN IN TRATTAMENTO ROENTGEN-CHEMIOTERAPICO, IMMUNODEPRESSO]
No full textDerangment of IL-2 receptor expression associated with growing IL-2 plasma levels in juvenile form of food-induceded migraine
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