1,721,003 research outputs found
Some model for the generalization of the binomial distribution: algorithms and applications
Generation and enumeration of atoms in the presence of logical constraints through binary trees
Un modello semi-Markoviano omogeneo con reward: applicazione alle malattie professionali invalidanti
HIV evolution: a quantification of the effects due to age and to medical progress
Abstract. This paper offers an analysis of HIV/AIDS dynamics, defined by CD4 levels and Viral
load, carried out from a macroscopic point of view by means of a general stochastic model. The
model focuses on the patient’s age as a relevant factor to forecast the transitions among the different
levels of seriousness of the disease and simultaneously on the chronological time. The third
model considers the two previous features simultaneously. In this way it is possible to quantify the
medical scientific progresses due to the advances in the treatment of the HIV. The analyses have
been performed through non-homogeneous semi-Markov processes. These models have been implemented
by using real data provided by ISS (Istituto Superiore di Sanità, Rome, Italy). They refer
to 2159 subjects enrolled in Italian public structures from September 1983 to January 2006. The
relevant results include also the survival analysis of the infected patients. The computed conditional
probabilities show the different responses of the subjects depending on their ages and the elapsing
of time
Bioimpedance analysis and resting energy expenditure in undernourished and refed anorectic patients.
ABSTRACT
Anthropometry, bioimpedance analysis (BIA) and resting energy expenditure (REE) were evaluated in young female patients affected by anorexia nervosa who were either severely malnourished (MnA) or already refed (RfA) and in a control group of healthy young women (WnC). Fat-free mass (FFM) and fat mass (FM), evaluated from skinfold thickness, were severely decreased in the MnA group while they were very similar in the RfA group and in the WnC group. With respect to BIA parameters, impedance (Z) was significantly higher in absolute terms in the MnA but lower than in the other groups when expressed as specific impedance, i.e. after normalization for both FFM and height. Phase angle significantly differed between the three groups, being significantly (P < 0.01) lower in the MnA (3.70+/- 0.83 degrees) and the RfA (4.36 +/- 0.82) than in the WnC (5.17 +/- 0.40). REE was comparable in RfA subjects and WnC subjects, while it was sharply decreased (P < 0.01) in the MnA patients both in absolute value and after adjustment for body composition (FFM and FM) or body weight. This cross-sectional study shows that marked changes in BIA parameters occur in undernourished anorectic patients and also in the anorectic subjects who were previously very underweight but studied only after having already regained a normal body size. REE was deeply decreased in the undernourished anorectic women even when the differences in body composition or Wt were taken into account, indicating the occurrence of a significant adaptation of energy expenditure to chronic underfeeding
The Aggregate Claim Amount and the Claim Number Discrete Time Homogeneous and Non-Homogeneous Semi-Markov Models: An Algorithmic Approach
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