1,721,369 research outputs found
Use of myocardial imaging to identify and manage subclinical heart disease in thyroid and other endocrine diseases
No full textIntegrated analysis of erythrocyte Na+/H+ antiport activity and left ventricular myocardial function in type I insulin-dependent diabetes mellitus.
No full textMembrane NA+/H+ exchanger regulates cell pH, volume, and growth. Abnormal activities have been reported in essential hypertension and type I insulin-dependent diabetes mellitus (IDDM). The aim of this study was to analyze the relationship between erythrocyte NA+/H+ antiport activity and myocardial anatomical and functional parameters in normotensive type I insulin-dependent diabetic patients. We evaluated 26 insulin-dependent diabetic patients (20 normo- and 6 microalbuminuric) and 17 age- and sex-matched healthy controls. Plasma and urine analytes as well as erythrocyte NA+/H+ antiport rate were measured. M-Mode- and 2D echocardiograms with Doppler analysis were performed in all subjects. Diabetic people, both normo- and microalbuminuric, had a Na+/H+ antiport activity significantly higher than control subjects (p < 0.01). All echocardiographic parameters relative to left ventricular volume, cardiac mass and systolic function overlapped in the study groups. Of Doppler indexes, evaluating the left ventricular diastolic filling, the late peak flow velocity (peak A) was significantly higher in diabetic patients (p < 0.01). E/A ratio was heightened in the control group compared to diabetics, as a whole as well separately considered (p < 0.01). Antiport significantly correlated with PWTh, STh, E/A, UAER, serum sodium, and gender (p < 0.0001). The linear and significant correlation found between Na+/H+ exchange and some cardiac indexes suggest the increased Na+/H+ antiport activity as possible predictive risk factor for the development of diabetic cardiomyopathy
2D-Strain in the evaluation of early alterations of global and regional left ventricular function in pre-hypertension
No full textRecenti applicazioni delle nuove metodiche ultrasoniche allo studio della cardiopatia ipertensiva,
No full textVALUTAZIONE DELLA RISPOSTA CARDIACA ALLO SFORZO ISOMETRICO ED ISOTONICO MEDIANTE ECG DINAMICO NELLA SINDROME DI WPW
No full textEarly myocardial alterations in subclinical hypothyroidism (SH): an ultrasonic tissue characterization backscatter anaysis
No full textMyocardial Tissue Characterization and Aortic Stenosis
No full textIn this issue of JASE, Fijalkowski et al.(1) describe an improvement in myocardial reflectivity induced by aortic valve replacement (AVR) in severe aortic stenosis (AS), using integrated backscatter (IBS) analysis, one of the ultrasonic methods for tissue characterization currently available. Furthermore, they found that IBS parameters have a predictive value for left ventricular (LV) reverse remodeling after AVR. The study population consisted of 58 patients with severe AS who were followed up for an average of 18 +/- 5 months after AVR. The authors observed a significant reduction of LV mass index and a significant increase in IBS mean cyclic variation and a decrease in the absolute end-diastole IBS intensity after AVR, showing an improvement of ultrasonic myocardial properties after AVR. They also demonstrated that preoperative analysis of IBS parameters might provide additional information to predict LV reverse remodeling in patients with a mean duration of 1.5 years of follow-up after AVR
Cyclic variation of the myocardial integrated backscatter signal and geometric remodelling in essential arterial hypertension
No full textCombining blood flow and tissue Doppler imaging with N-terminal pro-type B natriuretic peptide for risk stratification of clinically stable patients with systolic heart failure
No full textThis study was designed to ascertain whether the combination of Doppler assessment of the ratio of mitral blood flow to myocardial early diastolic velocities (E/E(m) ratio) and plasma N-terminal pro-type B natriuretic peptide (NT-proBNP) testing is useful to better stratify patients with stable systolic heart failure (HF). A total of 362 outpatients with chronic systolic HF (left ventricular ejection fraction = 12), 77% in those with the E/E(m) ratio in the intermediate third, and 86% in those with the E/E(m) ratio in the lower third (< 7) (P < 0.0001). By stratifying patients according to NT-proBNP above the median, patients' outcome was predicted in 13 out of 17 in the intermediate third (P = 0.002) and in 9 out of 10 in the lower third of E/E(m) ratio (P= 0.005). In patients with stable HF categorized according to the E/E(m) ratio, NT-proBNP testing improves risk stratification, particularly in those with minor degrees of diastolic dysfunction
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