27 research outputs found
Resting stages abundance in the biogenic sediment fraction from the deep Mediterranean Sea
No full textApproaches to the ethology of hydroids and medusae (Cnidaria, Hydrozoa)
No full textThe behavioural patterns of 26 species of Antho- and Leptomedusae (with or without medusa stage) were investigated by video recordings. The analysed activities were: answers to mechanical stimuli, prey capture and ingestion, digestion, egestion, and swimming. The quantity of behavioural patterns identified in the small number of hydrozoan diversity studied so far is sufficient to demonstrate that these supposedly "simple" animals have evolved a complex array of responses to both external and internal stimuli
Correlation between neuropsychometric tests and semiquantitative evaluation of the regional cerebral blood flow (rCBF) in a group of outpatients affected by cognitive impairment.
No full text
Clinical and Biochemical Implications of Hyaluronic Acid in Musculoskeletal Rehabilitation: A Comprehensive Review
No full textHyaluronic acid (HA) naturally occurs as a biopolymer in the human body, primarily in connective tissues like joints and skin. Functioning as a vital element of synovial fluid, it lubricates joints, facilitating fluid movement and diminishing bone friction to protect articular well-being. Its distinctive attributes encompass notable viscosity and water retention capacities, ensuring flexibility and absorbing shock during motion. Furthermore, HA has gained significant attention for its potential benefits in various medical applications, including rehabilitation. Ongoing research explores its properties and functions, especially its biomedical applications in several clinical trials, with a focus on its role in improving rehabilitation outcomes. But the clinical and biochemical implications of HA in musculoskeletal rehabilitation have yet to be fully explored. This review thoroughly investigates the properties and functions of HA while highlighting its biomedical applications in different clinical trials, with a special emphasis on its role in rehabilitation. The presented findings provide evidence that HA, as a natural substance, enhances the outcomes of musculoskeletal rehabilitation through its exceptional mechanical and biochemical effects
Novel Synthesis of Zinc Oxide Nanoparticles from Type IV Deep Eutectic Solvents
No full textOne of the fields where DES show remarkable added-values is the synthesis of inorganic materials, in particular nanoparticles. In this field, the inherent and highly-tunable nano-homogeneities of DES structure give origin to a marked templating effect, a precious role that has led to the recent bloom of a vast number of studies exploiting these new synthesis media to prepare nanomaterials and composite structures of various kinds. In this contribution, three examples of synthesis of nanoparticles containing zinc, using metal type-IV Deep Eutectic Solvents, a pathway that has never been explored so far, is described. The prepared materials have layered shapes, and when zinc nitrate is used as DES component, pure layered ZnO is obtained, forming nanometric platelets that assemble to form flower-like aggregates. The prepared nanoparticles show intrinsic fluorescence, and are being further studied to set up sensors for the detection of various contaminants
Biochemical Mechanisms and Rehabilitation Strategies in Osteoporosis-Related Pain: A Systematic Review
No full textBackground/Objectives: Osteoporosis causes a bone mass reduction and often determines acute and chronic pain. Understanding the biochemical and neurophysiological mechanisms behind this pain is crucial for developing new, effective rehabilitative and therapeutic approaches. This systematic review synthesizes recent advances in muscle–bone interactions and molecular pathways related to osteoporosis-associated pain. Methods: We carried out a systematic review including studies
published from 2018 to 2024 using PubMed, Scopus, clinicaltrials.gov and Cochrane Library. The Cochrane Collaboration tool was used to assess bias risk. The review adhered to PRISMA guidelines and is registered with PROSPERO (CRD42024574456); Results: Thirteen studies were included. It emerged that osteoporosis causes progressive bone loss due to disruptions in biochemical processes and muscle–bone interactions. This condition is also closely associated with the development of pain, both acute and chronic. Key findings include the role of the miR-92a-3p/PTEN/AKT pathway and
the impact of muscle–bone disconnection on bone health. Mechanotransduction is critical for bone maintenance. Effective pain management and rehabilitation strategies include physical therapy and physical exercise, yoga, Pilates, and cognitive behavioral therapy (CBT); they all improve pain relief and functional outcomes by enhancing muscle strength, flexibility, and balance. Pharmacological options such as NSAIDs, opioids, and new agents like SHR-1222, along with surgical interventions like percutaneous vertebroplasty, offer additional pain reduction, especially when included in individualized
rehabilitation projects; Conclusions: This review highlights advancements in understanding
osteoporotic pain mechanisms and identifies promising treatments. Integrating targeted therapies
and rehabilitation strategies can enhance patients’ pain relief
Medial or Lateral, That Is the Question: A Retrospective Study to Compare Two Injection Techniques in the Treatment of Knee Osteoarthritis Pain with Hyaluronic Acid
No full textBackground: Mild-to-moderate knee osteoarthritis (KOA) can be successfully treated using intra-articular hyaluronic acid (IA-HA). The medial infrapatellar (MIP) approach and lateral infrapatellar (LIP) approach are two of the most used techniques for performing IA-HA, but it is still not clear which one is preferable. Objectives: The study aims to find the best knee injection technique between MIP and LIP approaches. Methods: In total, 161 patients were enrolled, divided into two groups (MIP or LIP). Each technique was performed once a week for three weeks. Patients were evaluated using the Numeric Rating Scale (NRS), Knee Injury and Osteoarthritis Outcome Score (KOOS) and Roles and Maudsley Score (RMS) at T0 (before the first injection), T1 (one week after the third injection) and T2 (six months after). Results: NRS, KOOS and RMS showed a statistically significant improvement in both groups at all the detection times, without significant differences. No differences were detected between the groups in terms of systemic effect effusions, while the MIP group presented a mildly higher number of bruises in comparison with the LIP group (p = 0.034). Conclusions: Both the IA-HA techniques are equally effective in measured outcomes. The MIP approach seems to produce some local and transient side effects. So, the choice of the LIP or MIP approach depends on the operator’s skill and experience
NOVEL SYNTHESIS OF METAL OXIDE NANOPARTICLES FROM TYPE IV DEEP EUTECTIC SOLVENTS
No full textOne of the fields where DES show remarkable added-values is the synthesis of inorganic
materials, in particular nanoparticles. In this field, the inherent and highly-tunable nano homogeneities of DES structure give origin to a marked templating effect, a precious role that
has led to the recent bloom of a vast number of studies exploiting these new synthesis media to
prepare nanomaterials and composite structures of various kinds. In this contribution, the most
recent developments in the field will be reviewed and some exciting examples of novel metal
oxide nanoparticles syntheses using non-toxic type-IV Deep Eutectic Solvents will be
described. The prepared materials possess nanometric dimensions and show flower-like/thin layered shapes. Use of the prepared nanoparticles as fluorescent materials for the detection of
various contaminants is under development
