1,720,977 research outputs found
Prognostic value of differential expression of Laminin-5 gamma2 in oral squamous cell carcinomas: Correlation with survival
No full textAnamnestic Factors and Functional aspects in the selection of patients with migrainous vertigo
No full textSignaling function of beta-catenin in human oral squamous carcinoma cell lines: a confocal laser scanning microscopy study
No full textInvading islands in oral squamous cell carcinomas positive for SMAC/DIABLO and cytochrome c: an immunohistochemical study on the possible activation of apoptotic pathways
No full textMonterenzio (prov. De Bologne) : la nécropole celto-etrusque de Monterenzio Vecchio
No full textUna quarantina di tombe scavate fra il 2000 e il 2005, a cui si aggiungono un'altra mezza dozzina di sepolture individuate nel 1988, forniscono un quadro sorprendente del rituale funerario etrusco-celtico dell'Appennino bolognese. La parte conservata della necropoli copre un breve lasso di tempo che va dalla fine del IV sec. a.C. all'inizio del III sec. a.C. I dati archeologici del territorio cispadano, relativi ai Boi e ai Senoni, testimoniano una marcata influenza mediterranea. e una non totale adesione, da parte delle comunità transalpine ai modelli etruschi
Prognostic value of differential expression of Laminin-5gamma2 in oral squamous cell carcinomas: correlation to survival
No full textIn oral squamous cell carcinomas of the head and neck, Laminin-5 γ2 has been associated with tissue invasion, lymph node metastasis and histopathological grading. In the present study, we compared the expression of the subunit γ2 of Laminin-5 under normal, dysplastic and invading epithelia in 65 biopsies previously diagnosed for oral squamous cell carcinoma. The number of γ2-positive cells were analyzed in relation to patients' survival, tumor grading, size of the lesion, TNM stage, histopathological pattern of invasion and inflammatory reaction. Biopsies of oral squamous cell carcinomas were deparaffinised, processed for antigen unmasking procedures and stained with antibody anti-Laminin-5 γ2. By light microscopy, 4 optical fields of x200 were selected in three different areas including normal, dysplastic and invading epithelia. Positive cells were counted and divided into three categories, which included 50 stained cells. Patient survival was analyzed by Kaplan-Mayer curves. γ2-positive cells were found in the basal layer of dysplastic epithelium, within inflammatory infiltrate, at the margins of differentiated invading islands and at the forefront of undifferentiated invading nests. Observations showed that an increased number of γ2-positive cells correlated significantly with a shorter life expectancy under invading epithelia (log-rank test p<0.05), not when a count was performed under normal or dysplastic epithelia of the same patient. The number of γ2-positive cells also correlated with the histopathological pattern of invasion. Our results show that γ2 may be a reliable prognostic tool for oral squamous cell carcinomas
Prognostic value of differential expression of Laminin-5 in oral squamous cell carcinomas: correlation with survival.
No full textΚατὰ τόν ποταμόν. Un arsenale navale sulla via per Spina
No full textIl contributo fornisce una sintesi non esaustiva e preliminare dei risultati delle campagne di scavo effettuate a Comacchio, nella zona di Valle Pega, lungo Strada Fiume, nel 2017 e 2021 dalla Soprintendenza ABAP per la città metropolitana di Bologna e le province di Modena, Reggio Emilia e Ferrara. L’area indagata ha restituito le evidenze di un edificio monumentale di epoca ellenistica, per il quale si propone l’identificazione con un neorion (arsenale navale), sorto in stretta correlazione con un bacino di acque interne, la cui planimetria e tecnica costruttiva, non trovano attualmente confronti in ambito spinetico e, più in generale, in ambito deltizio. Lo studio affronta specificamente l’esame dei reperti ceramici, dei laterizi, dei materiali numismatici e della malacofauna
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