1,721,789 research outputs found
A High De Ritis Ratio is Associated with Mortality in Adult Trauma Patients
No full textChing-Hua Tsai, Ting-Min Hsieh, Shiun-Yuan Hsu, Ching-Hua Hsieh Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, 83301, TaiwanCorrespondence: Ching-Hua Hsieh, Tel +886-7-7327476, Email [email protected]: The De Ritis ratio, which is the ratio of aspartate aminotransferase (AST) to alanine aminotransferase (ALT), has been suggested as a potential prognostic marker for various diseases. This study aimed to investigate the association between the De Ritis ratio and in-hospital mortality in adult trauma patients.Methods: A total of 17,472 adult trauma patients hospitalized between January 1, 2009, and December 31, 2020, were allocated into groups according to the De Ritis ratio. The normal range of the De Ritis ratio was calculated from 3320 individuals in the National Taiwan Biobank. Statistical analyses were performed using SPSS software.Results: Patients with a De Ritis ratio > 1.6 had a significantly higher in-hospital mortality rate (7.3% vs 1.5%, odds ratio 5.29; Q1–Q3 2.72– 10.30; p 1.6 may serve as an early prognostic tool to identify adult trauma patients at high risk of in-hospital mortality.Keywords: aspartate aminotransferase, AST, alanine aminotransferase, ALT, De Ritis ratio, in-hospital mortality, traum
Predictive Role of De Ritis Ratio in Biochemical Recurrence After Radical Prostatectomy
No full textAim:To analyze the role of De Ritis (aspartate aminotransferase/alanine aminotransferase) ratio in predicting biochemical recurrence (BCR) after radical prostatectomy (RP).Methods:We retrospectively evaluated 425 patients with localised prostate cancer who underwent RP from 2009 to 2018. Patients with neo-adjuvant treatment, elevated liver enzymes, postoperative early hormone therapy, incomplete clinicopathological data and a follow-up of less than 6 months were excluded from the study. Demographic, clinical, pathological and follow-up data of the patients were recorded. Patients with and without BCR were compared. Sensitivity and specificity of De Ritis ratio in predicting BCR were calculated.Results:According to the maximum value of the Youden index, optimal threshold of De Ritis ratio for BCR was 1.1. Sensitivity, specificity, positive predictive value and negative predictive value were 69.7%, 61.1%, 37.6% and 85.7%, respectively. Multivariate analysis showed that the De Ritis ratio (HR=1.968, p=0.014) was a significant predictor factor for BCR. BCR-free survival rate was significantly lower in patients with higher De Ritis ratio.Conclusion:Our study suggests that elevated De Ritis ratio and detailed pathological findings could be an independent predictive factor for BCR after RP
Il modello societario quale via preferibile per l’esercizio di attività sportiva dilettantistica: il lucro attenuato
No full textThe article examines the legal evolution of amateur sports, focusing on
the emergence of a model of “attenuated profit” for sports companies. The
author argues that corporate forms are preferable to associations due to
greater managerial efficiency and statutory flexibility. The new rules allow a
limited distribution of profits within strict limits, applicable only to specific
capital companies. The analysis addresses interactions with Third Sector
regulation and exemptions from democratic principles for corporations.L’articolo analizza le trasformazioni normative che hanno interessato
lo sport dilettantistico, evidenziando il progressivo riconoscimento di una
forma di “lucro attenuato” nelle società sportive. L’autore sostiene la preferibilità del modello societario rispetto a quello associativo, per efficienza
gestionale e flessibilità statutaria. La nuova disciplina consente una limitata
distribuzione degli utili, entro rigorosi limiti, esclusivamente a favore di alcune società di capitali. Si approfondisce il coordinamento con la normativa
del Terzo settore e le deroghe ai principi i di democraticità per le società
Prehipertansif Hastalarda De Ritis Oranı ve Glasgow Prognostik Skorunun Önemi
Get PDFAim: To evaluate Glasgow prognostic score (GPS) and De Ritis ratio in optimal blood pressure and prehypertensive patients, and investigate whether these parameters can predict antihypertensive treatment in the follow-up period. Methods: A total of 402 patients who were followed up with a 24-hour ambulatory blood pressure with a pre-diagnosis of hypertension between January 2018 and December 2018 were included in the study. Routine laboratory parameters of the patients were recorded in the hospital digital system. The common health system data of the patients was analyzed until June 2020, and those who were started on antihypertensive treatment were recorded. Results: 402 patients (mean age 40.16 ± 13.01 years, 49% male) were included in the study. 226 of these were in prehypertension group. The mean GPS and the De Ritis ratio, aspartate aminotransferase levels, mean systolic and diastolic blood pressures were different between the groups (p=0.035, p=0.023, p=0.039, p<0.001 and p=0.012, respectively). When patients whose antihypertensive treatment was started and those who did not receive antihypertensive treatment were compared; age, De Ritis ratio and mean diastolic blood pressure differed between the two subgroups (p<0.001, p=0.015 and p=0.040, respectively). Multivariate logistic regression analysis showed that De Ritis ratio and age were, independently, predictors for antihypertensive treatment (OR:3.064, p=0.015 and OR:1.050, p= 0.001 respectively). In ROC curve analysis, both age and De Ritis ratio were successful at predicting the initiation of antihypertensive treatment with an AUC:0.697 and p<0.001 and AUC:0.630 and p=0.018 respectively. Conclusions: Both GPS and the De Ritis ratio were found to be significantly higher in prehypertensive patients than those with optimal blood pressure. Moreover, the De Ritis ratio, an easily calculated laboratory parameter, can be used as a predictive value for antihypertensive treatment
Vincenzio de Ritis e i metri arabi nella Napoli di inizio 800
No full textVincenzo de Ritis is the author of The Arabs’ Metres, a noteworthy report on Arab prosody, presented at the Accademia Pontaniana of Naples in 1829 and published in 1833. In this work, de Ritis offers a reading of ‘ilm al-‘arud, paying special attention in the first part to the similarities between the Arabic and the Latin and Greek prosody traditions, devoting an entire section to the Hazrajiyya poem. In the second part, he presents the Arab metres through numerous poetical examples. Vincenzo de Ritis’ work, ideally located in the golden age of Arab metric scholarship, places Italy within a wider international context, in sync with the studies of G. Ewald, A.I. Silvetsre de Sacy, G. Freytag
De Ritis ratio (AST/ALT) as an independent predictor of poor outcome in patients with acute ischemic stroke
No full textFan Gao,1 Chen Chen,2 Jun Lu,1 Jie Zheng,1 Xian-Cang Ma,1,3 Xing-Yun Yuan,2 Kang Huo,2 Jian-Feng Han2 1Clinical Research Center, 2Department of Neurology, 3Department of Psychiatry, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China Purpose: The aspartate transaminase/alanine transaminase ratio (De Ritis ratio, AAR) was reported to be associated with patients’ prognosis in certain diseases recently. The objective of the current study was to determine the association between the AAR at admission and poor outcome at 3 months in acute ischemic stroke (AIS) patients.Patients and methods: This retrospective cohort study included patients who experienced their first-ever AIS between June 2015 and March 2016. The primary outcome measure was a poor outcome at 3 months (modified Rankin Scale score >2). Multivariate logistic regression models were used to assess the relationship between AAR quartiles and clinical outcomes among the AIS patients. Receiver operating characteristic curve analysis was applied to identify the optimal cutoff for AAR in predicting the prognosis of AIS.Results: In terms of the relationship between poor outcome and AAR, the adjusted odds ratio comparing the highest and lowest AAR quartiles was 2.15 (95% confidence interval =1.14–4.05). An AAR of 1.53 was identified as the optimal cutoff. In a prespecified subgroup analysis according to the time from symptom onset to treatment (>24 vs ≤24 hours), there was no significant difference in the effect of AAR >1.53 between the two groups.Conclusion: An increased AAR at admission is significantly associated with a poor outcome at 3 months in AIS patients. Keywords: De Ritis ratio, stroke, prognosis, aspartate transaminase, alanine transaminase, modified Rankin scale, poor outcom
De Ritis ratio as a predictor of 1-year mortality after burn surgery
No full textBackground: Burn is an overwhelming injury. The De Ritis ratio, defined as aspartate aminotransferase to alanine aminotransferase ratio, can be used to predict poor outcomes. We evaluated the risk factors, including the De Ritis ratio, associated with 1-year mortality after burn surgery.
Methods: Patients who underwent burn surgery from 2009 to 2019 were retrospectively evaluated. Multivariate Cox regression analysis was conducted to evaluate the risk factors for 1-year mortality after burn surgery. Receiver operating characteristic (ROC) curve analysis of the De Ritis ratio was performed to predict postoperative 1-year mortality. Kaplan-Meier survival analysis was also conducted. Other postoperative outcomes, such as durations of hospital and intensive care unit stays, acute kidney injury, and major adverse cardiac events, were evaluated.
Results: One-year mortality after burn surgery occurred in 247 (19.9%) of 1244 patients. The risk factors for 1-year mortality after burn surgery were the De Ritis ratio, age, American Society of Anesthesiologists physical status, diabetes mellitus, total body surface area burned, inhalation injury, serum creatinine level, and serum albumin level. The area under the ROC curve for the De Ritis ratio was 0.716 (optimal cutoff=1.9). The 1-year mortality rate after burn surgery was significantly higher in patients with a De Ritis ratio >1.9 than in those with a De Ritis ratio ≤1.9 (35.8% vs. 11.8%, P<0.001). The survival rate was significantly higher in patients with a De Ritis ratio ≤1.9 than in those with a De Ritis ratio >1.9 (log-rank test, P<0.001). Intensive care unit stay, acute kidney injury, and major adverse cardiac events were significantly higher in patients with a De Ritis ratio >1.9 than in those with a De Ritis ratio ≤1.9 (P=0.006, P<0.001, and P<0.001, respectively).
Conclusions: The preoperative De Ritis ratio was a risk factor for 1-year mortality after burn surgery. The De Ritis ratio >1.9 was significantly associated with an increased 1-year mortality after burn surgery. These findings emphasized the importance of identifying burn patients with an increased De Ritis ratio to reduce the mortality after burn surgery
Dell'associazione in partecipazione. Commento all'art. 2549 c.c.
No full textNel commento alle disposizioni del codice civile dettate in tema di associazione in partecipazione, vengono affrontati i singoli problemi che sorgono dalle disposizioni, quali la partecipazione alle perdite dell'associato, la rendicontazione, le possibili clausole atte ad integrare le regole legali, i limiti all'autonomia privata. Particolare attenzione è prestata alle tipologie di apporti dell'associato ed ai consequenziali obblighi a carico delle parti anche relativamente all'obbligo di restituzione a carico dell'associante al termine del rapporto. Nel lavoro si tratta anche della differenza tra cointeressenza propria e impropria e sono delineate le differenze con l'associazione in partecipazion
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