1,724,182 research outputs found
Indigenous students’ beliefs about science
No full textResearch shows that Australia’s Indigenous 15-year-olds are more environmentally aware and have higher levels of belief in the value of science than their non-Indigenous peers. Lisa De Bortoli reports
EXPERIÊNCIA NA UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO, CAMPUS SÃO MATEUS
Full text linkEsse trabalho relata a experiência profissional da Profa. Valquíria Camin de Bortoli na Universidade Federal do Espírito Santo, campus São Mateus, onde vem desenvolvendo diversos projetos de pesquisa, ensino e extensão
Maths + confidence = higher scores for boys
No full textTeenage boys outperform Australian girls in mathematics by the equivalent of about one-third of a school year, according to the latest PISA survey, as Sue Thomson and Lisa De Bortoli explain
Australia's Indigenous students and PISA 2000
No full textLisa de Bortoli and John Cressell analyse the OECD/Programme for International Student Assessment (PISA 2000) data on Australian Indigenous students in comparison with other Australian students and in relation to other countries. They also examine some of the characteristics of the Indigenous students
Unspecified intestinal malabsorption in patients treated with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers: a retrospective analysis in primary care settings
No full textObjective: To investigate the possible relationship between the use of Angiotensin II Receptor Blockers (ARBs) or Angiotensin-Converting-Enzyme Inhibitors (ACE-i) and unspecified intestinal malabsorption (IM) within the Italian and German real-life context. Research design and methods: a retrospective cohort of patients with a new unspecified IM diagnosis during the period 1 January 2010â31 December 2013 was extracted from Italian IMS Health Longitudinal Patient Database and German IMS Disease Analyzer. Only patients with at least one prescription of ARB or ACE-i medication during the 6Â months preceding the IM diagnosis were included and then followed up for 12Â months to assess treatment exposure. Results: After stratification by year and molecule, the proportion of patients experiencing an unspecified IM diagnosis on total patients receiving ARBs or ACE-i ranged from 0% to 0.14%, showing no relevant differences between molecules and no time trends. Conclusions: this study indicates that ACE-i or ARBs were rarely associated to an unspecified IM diagnosis. No relevant difference between each specific ACE-i and ARB was highlighted
PlayWithEyes: a new way to test children eyes.
No full textOne of the major problems of doctors when dealing with children is to capture and maintain their attention. This is particularly true for oculists that must test children eyes, especially if they are very young. In this paper we present PlayWithEyes, a serious game that aims at testing the children eyes while they are having fun playing with Lea symbols and images taken from popular cartoons, using a touch interface. PlayWithEyes was created to perform screening of visual acuity of very young children, since early diagnosis is very important for some sight defects like amblyopia (lazy eye)
MODELLIZZAZIONE DI SISTEMI DI GENERAZIONE DI ENERGIA ELETTRICA PER VIA EOLICA
No full textThe arguments of this PhD Thesis are divided in two parts: a first part regarding the development of control algorithms to optimize the efficiency of wind energy systems and, at the same time, to simplify the system structure avoiding the mechanical sensors.
The second part regards the analysis and design of axial flux permanent magnet generators for wind applications. Furthermore, I analyzed other particular aspects such as axial strengths and permanent magnet losses.Gli argomenti trattati in questa Tesi di Dottorato sono articolati in due parti. Una prima è rivolta allo sviluppo di algoritmi di controllo aventi lo scopo di ottimizzare la resa energetica di sistemi eolici consentendo allo stesso tempo una semplificazione del sistema stesso grazie all'assenza di sensori per la rilevazione di grandezze meccaniche.
La seconda parte riguarda l'analisi ed il progetto di generatori sincroni a flusso assiale a magneti permanenti da utilizzare in applicazioni eoliche. Sono stati inoltre analizzati particolari aspetti elettromagnetici quali gli sforzi assiali gravanti sulle parti statoriche e rotoriche ed il calcolo delle perdite per correnti indotte nei magneti permanenti
Characterization of ion channels in chloroplasts and mitochondria of land plants
Full text linkChloroplasts and mitochondria play essential roles in the plant physiology and are emerging as important players in intracellular Ca2+ signaling. A major role in the context of organellar ion homeostasis is played by ion channels. In fact, they are responsible for the regulation of ion distribution between compartments and they are proposed to guarantee Ca2+ signaling, proper osmotic potential, optimal pH for enzymatic activities and electron transport chains’ function. In plants, only a few of channel families have been found to localize to chloroplast/mitochondria and most of them have not been fully characterized. In addition, the molecular mechanisms by which chloroplasts and mitochondria accumulate and release Ca2+ are still far from being clarified. The present work aimed to characterize possible players in organellar Ca2+ flux-mediating systems in plants, namely the Ionotropic Glutamate Receptors (GLRs, non-selective cation channels) and Mitochondrial Calcium Uniporters (MCUs), combining reverse genetics, biochemistry and in vivo localization studies.
The research here presented allowed to deepen the study on land plant GLRs, to characterize two novel organellar channels of A. thaliana, i. e. AtGLR3.5 and AtMCU, and to lay the ground for the characterization of the Physcomitrella patens GLRS, PpGLRs, from different points of view. Results revealed additional variability of GLRs among photosynthetic organisms and support the role of GLRs in the regulation of various organellar processes such as photoprotective mechanisms, senescence and mitochondrial structure integrity maintenance. Importantly, the characterization of AtGLR3.5 provided the molecular identification of the first cation channel in plant mitochondria and the characterization of AtMCU1 and MICU allowed for the first time the proposal of a model for the existence and regulation of Ca2+ fluxes in plant mitochondria via MCU complex. The present work therefore contributed to add new knowledge to the field of the regulation of ion homeostasis, especially Ca2+ homeostasis, in mitochondria and chloroplasts.Cloroplasti e mitocondri hanno un ruolo fondamentale nella fisiologia vegetale e stanno emergendo come importanti attori nel signaling del Ca2+ intracellulare. Un ruolo fondamentale nel contesto dell’omeostasi ionica organellare è giocato dai canali ionici. Infatti essi sono responsabili della regolazione della distribuzione ionica fra compartimenti ed è stato proposto che contribuiscano a garantire il signaling del Ca2+, l’appropriato potenziale osmotico, il pH ottimale per le attività enzimatiche e il funzionamento delle catene di trasporto elettronico. Nelle piante, solo poche famiglie di canali sono state identificate in cloroplasti/mitocondri e la maggior parte di loro non è stata pienamente caratterizzata. Inoltre, il meccanismo molecolare attraverso cui cloroplasti e mitocondri accumulano e rilasciano Ca2+ è ancora lontano dall’essere chiarito. Lo scopo del presente lavoro è stato quello di caratterizzare possibili attori coinvolti nel nella mediazione dei flussi di Ca2+ organellari, in particolare i recettori ionotropici del glutammato (GLRs) e gli uniporti mitocondriali del calcio (MCU), combinando tecniche di genetica inversa, biochimica e studi di localizzazione in vivo.
La ricerca qui presentata ha permesso di approfondire lo studio sui GLR vegetali, di caratterizzare due nuovi canali organellari di A. thaliana, AtGLR3.5 e AtMCU, e di gettare le fondamenta per la caratterizzazione dei GLR di Physcomitrella patens, PpGLR, da diversi punti di vista. I risultati del lavoro hanno rivelato ulteriore variabilità dei GLR fra gli organismi fotosintetici e hanno mostrato come i GLR siano coinvolti nella regolazione di diversi processi organellari come i meccanismi di fotoprotezione, la senescenza e il mantenimento dell’integrità strutturale mitocondriale. La caratterizzazione di AtGLR3.5 ha permesso l’identificazione molecolare del primo canale cationico mitocondriale vegetale e la caratterizzazione di AtMCU1 ha permesso per la prima volta di proporre un modello che preveda l’esistenza e la regolazione dei flussi di Ca2+ nei mitocondri vegetali per mezzo del complesso MCU. Il lavoro qui presentato ha pertanto contribuito ad aggiungere nuova conoscenza al campo della regolazione dell’omeostasi ionica, specialmente l’omeostasi del Ca2+, nei mitocondri e nei cloroplasti
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