1,720,986 research outputs found
Valutazione su ampia scala del recupero epidermico funzionale dopo attivazione biomimetica
No full textNell’ambito di un progetto integrato del Centro di Cosmetologia Chimica dell’Università di Padova sono state messe in evidenza le correlazioni esistenti tra lo sbilanciamento delle forze inter e intramolecolari dovute al turnover cellulare epidermico ed il riflesso energetico da esse indotte a livello superficiale
Il TVS skin test
No full textL’applicazione topica per sua natura provoca delle perturbazioni che coinvolgono il dominio strutturale e superficiale del sistema-pelle con cui si viene a contatto.
Il TVS skin test si basa sulla misura del riflesso energetico superficiale indotto dallo sbilanciamento delle forze attrattive di coesione.
L’attività biosintetica epidermica e il turnover cellulare provocano uno sbilanciamento delle forze inter e intramolecolari che a livello superficiale si riflettono sottoforma di energia libera superficiale (ELS) nelle sue due componenti fondamentali dispersa (CD) e polare (CP).
Tale riflesso è stato misurato in vivo e in vitro per la prima volta nel Centro di Cosmetologia Chimica C.A. Benassi dell’Università di Padova
Bioadhesive topical application of tryptophan derivatives
No full textInnovative formulations with high affinity for biological substrates can be designed by exploiting the TVS tensiometric versus skin approach. Combining a compressed air continous-spray application system with biomimetic agents modulating the epidermal barrier (badsystem), bioadhesive topical application of tryptophan derivatives are well obtained without side effects. The biomimetic effect of tryptophan-badsystem was observed
Hydrophobic Eutectic Solvent-Based Dispersive Liquid-Liquid Microextraction Applied to the Analysis of Pesticides in Wine
Full text linkA green solvent-based DLLME/HPLC-MS method for the determination of 19 pesticides in wine samples has been developed. The extractant solvent is a hydrophobic eutectic mixture composed of L-menthol and butylated hydroxytoluene in a molar ratio of 3:1. The endogenous ethanol of wine has been used as dispersive solvent, in order to avoid the solidification of the extracts under 19◦C. The mobile phase composition, the elution gradient and the sample injection volume were optimized in order to make this hydrophobic mixture compatible with conventional reversed phase chromatography and electrospray ionization. The method was validated in matrix, using a wine free from the target compounds. Average recovery as high as 80%, precision between 3 and 14%, and limits of detection and quantification much lower than the maximum residue levels (MRLs) for grapes and wines fixed by the EU regulation, make this multiresidue method fitted for the purpose, with the further advantages of being quick, cheap and in compliance with the green analytical chemistry. From the analysis of 11 commercial wines it was found that just in a bio sample the target compounds were not detectable or lower than quantification limit; as for the other samples, the most widespread and abundant pesticides were methoxyfenozide and boscalid, but their levels were much lower than the relative MRLs
INTRODUCTION TO THE "TOPICAL DESIGN TVS"
No full textBy TVS* approach (Tensiometric Versus Skin), the superficial-skin free energy (SFE) and related polar (CP) and dispersed components (CD) have been measured in vivo and in the isolated epidermis and corneum layer. Topical design TVS is a conceptually innovative pathway in the design phase, development and evaluation of formulative prototypes intended for contact with the skin and mucous membranes [4,5]. A typical application is reporte
Tensiometric Versus Skin (TVS) modelling as improved approach for the direct evaluation of skin hydration
No full textHORSE-SKIN REACTIVITY EVALUATION BY TVS MODELING
No full textThe epidermis in man has a well defined biosintetic activity. In the granular layer are sintetized the lamellar bodies, also called Oddland bodies, successively fragmented in the stratum lucidum. The fragments which forms, after modifications, make a physiological barrier that has selective permeability.
The efficiency of the epidermal functional state was recently measured by TVS1 skin test. In this work has been used the tensiometric TVS model to characterize the skin of the horse and to evaluate the superficial energetic mudulations after biomimetic activatio
Bioadhesive application and dermatological evaluation of Valgrande (Dolimites) thermal water
No full textINTRODUCTION TO BIOADHESIVE TOPICAL DESIGN TVS: A CONCEPTUALLY INNOVATIVE PATHWAY IN THE DESIGN PHASE, DEVELOPMENT AND EFFICACY EVALUATION OF COSMETIC PRODUCTS
No full textCorrelation between epidermal tihickening and surface free energy reflex in patients operated for breast carcinoma by a combined ultrasound imaging and tenskinmetric analysis (TVS skin test). The influence of a biomimetic cosmetic-treatment.
No full textThe aims of this work were to establish the correlation between epidermal thickening, with functional changes in surface energy, which occurs in breast operated for cancer, and to evaluate the effect of cosmetic biomimetic activation on the recovery of the epidermal functional state of breast tissue. The combination of ultrasound imaging and TVS (tenskinmetric) techniques with liposomal application of well-defined energy (68.5 mN/m) in the form of a cosmetic biomimetic activator, can reveal in a sensitive and non-invasive way the surface energy epidermal functional state in both healthy and operated breast in various conditions. Tests were carried out chronologically in 14 women operated for mastectomy and/or quadrantectomy, followed by radiotherapy. An increase in mean skin thickening of about 50.5 %, with respect to healthy values, was measured, and an increase in mean epidermal energy after biomimetic activation. of about 176 %, with respect to baseline values
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