830 research outputs found

    Distal radius articular fractures: a comparison between ORIF with angular stability plate and percutaneous Kirschner wires.

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    Distal radius articular fractures: a comparison between ORIF with angular stability plate and percutaneous Kirschner wires. Tronci V1, Campochiaro G, Gazzotti G, Rebuzzi M, Tsatsis C, Catani F. Author information Abstract PURPOSE OF THE STUDY: To analize and compare vantages and disadvantages in long-term of two different techniques to treat distal radius articular fractures: ORIF with plate versus percutaneous pinning with K-wires. MATERIALS AND METHODS: We reviewed 77 distal radial articular fractures treated surgically from 2005 to 2009. Fractures were divided in two homogeneous groups according to patient age, gender, fracture-type and follow-up. The first group was treated with ORIF using angular stability volar plate, while the second one with closed reduction, K-wires percutaneous pinning and ante-brachial plaster casting. Functional outcomes were assessed with MAYO and DASH score, wrist range-of-movement and handgrip. Radiographic parameters were calculated in the post-operative and long-term x-rays. RESULTS: ORIF group showed better mean DASH and MAYO score, range of movement and handgrip strength compare to K-wires group. Expecially in type C fractures and in younger patients (<65 years). Minor differences were observed in type B fractures. About complications: two cases of surgically-treated medial nerve compression in ORIF group and one in K-wire group, one case of algodystrophy in K-wire group. Referring to radiographic parameters, long term values show data positive for ORIF. CONCLUSIONS: Though several studies about these techniques has been performed, but no scientific evidence proves the superiority of one surgical treatment. C-type need to be treated with plate in young patients or in elderly patients with high functional demand. Elderly patients with low functional demand can achieve satisfactory results also with percutaneous pinning, especially in Btype fractures

    Cantori and dynamical localization in the Bunimovich Stadium

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    Classical and quantum properties of the Bunimovich stadium in the diffusive regime are reviewed. In particular, the quantum properties are directly investigated using an approximate quantum map. Different localized regimes are found, namely, perturbative, quasi-integrable (due to classical Can- tori), dynamical and ergodic

    Standard model Higgs-boson branching ratios with uncertainties.

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    We present an update of the branching ratios for Higgs-boson decays in the Standard Model. We list results for all relevant branching ratios together with corresponding uncertainties resulting from input parameters and missing higher-order corrections. As sources of parametric uncertainties we include the masses of the charm, bottom, and top quarks as well as the QCD coupling constant. We compare our results with other predictions in the literature.Peer Reviewe

    Measurement of D*+/- meson production in jets from pp collisions at √s = 7 TeV with the ATLAS detector

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    This paper reports a measurement of D*± meson production in jets from proton-proton collisions at a center-of-mass energy of √s=7 TeV at the CERN Large Hadron Collider. The measurement is based on a data sample recorded with the ATLAS detector with an integrated luminosity of 0.30 pb-1 for jets with transverse momentum between 25 and 70 GeV in the pseudorapidity range |η|<2.5. D*± mesons found in jets are fully reconstructed in the decay chain: D*+→D0π+, D0→K-π+, and its charge conjugate. The production rate is found to be N(D*±)/N(jet)=0.025±0.001(stat.)±0.004(syst.) for D*± mesons that carry a fraction z of the jet momentum in the range 0.3<z<1. Monte Carlo predictions fail to describe the data at small values of z, and this is most marked at low jet transverse momentum

    Multiple systemic treatment options in a patient with malignant tenosynovial giant cell tumour

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    Tenosynovial giant cell tumour (TGCT) is a group of rare soft tissues neoplasia affecting synovial joints, bursae and tendon sheaths and is classified as localized type or diffuse type. The diffuse type (TGCT-D), also known as 'pigmented villonodular (teno)synovitis' is characterized by local aggressivity, with invasion and destruction of adjacent soft-tissue structures, and high local recurrence rate. Radical surgery remains the standard therapy while adjuvant radiotherapy may help to control local spread. Malignant TGCT is characterized by high rate of local recurrences and distant metastasis. Few cases of malignant TGCT and very few evidences on systemic therapies are described in the literature, so, to date, no systemic treatment is approved for this rare disease. We report the case of a malignant TGCT patient treated with many different systemic therapies, including chemotherapy and tyrosine-kinase inhibitors, and performed a review of the literature on the systemic treatment options of this rare tumour

    Gastrointestinal stromal tumors and second primary malignancies: a retrospective monocentric analysis

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    In the post-Imatinib era, the median survival of patients diagnosed with GIST has reached almost 5 years. Prolonging GIST-specific survival, GIST patients have an increased incidence of secondary neoplasia. Data on the prognostic impact of second tumors in GIST patients are very poor with few and small retrospective analyses available in the literature. We conducted a retrospective monocentric analysis on 145 patients diagnosed with GIST between April 2001 and October 2018. Kaplan-Meier and Cox hazard methods were used for survival analysis. A total of 154 GIST patients were included and 31 patients of them (21%) were diagnosed with at least one additional malignancy. The most common second tumors associated with GIST were gastrointestinal tumors. GIST patients with additional malignancies showed to have lower size (&gt;5 cm: 35% vs 45%; p = 0.75), higher mitotic rate (&gt; 5/50 HPFs: 42% vs 29%; p = 0.24), higher presence of cKIT mutation (85% vs 69%), a lower presence of PDGFRα mutation (8% vs 17%; p = 0.05) and shorter survival (mOS: 9.6 vs 15.5 years; p = 0.30). In conclusion, our study did not find any significant correlation between clinicopathological characteristics and the development of a second tumor in GIST patients. Further analyses and strict follow up protocols are needed in order to early diagnose and promptly treat a second primary tumor in the GIST population
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