139 research outputs found

    Pigmented villonodular bursitis (PVNB) in the medial gastrocnemius bursa:report of an unusual case.

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    INTRODUCTION: Pigmented villonodular synovitis (PVNS) represents an uncommon benign proliferative disorder that may involve the synovium of the joint diffusely or focally, or that may occur extraarticularly in a bursa (pigmented villonodular bursitis [PVNB]) or tendon sheath (pigmented villonodular tenosynovitis [PVNTS]). The knee, followed by the hip, is the most common location for PVNS or PVNB, whereas PVNTS occurs most often in the hand and foot. It primarily involves young adults, the peak age being between the second and fourth decade of life and appears with non-specific symptoms which mimic other pathologies, including traumatic knee injuries, thus often delaying the correct diagnosis. REPORT/DISCUSSION: A 17 year old female presented with swelling and mild degree of pain in her left knee for three months. No history of trauma or any other significant illness was present. Routine laboratory investigations were normal. X-ray was normal. MRI of the knee was performed and it showed a joint effusion with non-specific synovial proliferation and two focal nodular formations at the insertion of medial head of gastrocnemius muscle in the medial gastrocnemius bursa. Those two nodular formations had low signal intensity on all pulse sequences and bloom artifacts on the FGRE-sequence. T1 weighted fat-saturated gadolinium enhanced MR image showed a low marginal contrast-enhancement of the two nodular formations, and high contrast-enhancement of the synovial proliferation. Biopsy from the two lobulated nodules revealed synovial nodules which contained haemosiderin pigment. Imaging characteristics of PVNS and PVNB are almost the same: radiographically visible calcifications are rare; CT scans show the lesions as high attenuating because of the haemosiderin content; MRI findings are prominent low signal intensity (seen with T2-weighting) and "blooming" artifacts from the hemosiderin deposits (seen with gradient-echo sequences) that are nearly pathognomonic. In addition, MR imaging is optimal for evaluating lesion extent. This information is crucial to guide treatment and to achieve complete surgical resection

    Organizzazione Centro-Sud Trapianti: Outcome analysis 1999 to 2002

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    Background. The Organizzazione Centro-Sud Trapianti (OCST), which was created in 1998, is organized into eight regional areas, each referring to a local Regional Transplant Coordinating Center. Organs are primarily allocated to meet the demands of transplant C, centers in each regional area. Urgencies, pediatric grafts, and paybacks are managed by an Interregional Transplant Coordinating Center. The aim of the current work is to report on the impact of introduction of OCST on organ donation and transplant activity over the period from 1999 to 2002. Materials and methods. A retrospective analysis of donor and transplant data charts over the period from 1999 to 2002 focused on outcome analysis based on donor epidemiological data, cause of death, reasons for discards and grafts performed at OCST local transplant centers. Results. From 1999 to 2002, we observed a remarkable increase in organ donation from 8.8 to 22.5 donors per million people. Donor epidemiology showed an increase in median a(ye and stroke incidence rates and a decrease in trauma cases. The nonharvested donor rate rose steadily over the study period, plateauing at 58%, which was compensated for by a threefold increase in donation. Family oppositions ranged as high as 35.5% on average, despite public efforts to support donation. Transplant activity rose by 76%. Conclusions. The institution of OCST and the efforts from central and regional authorities have yielded a significant increase in organ donation and transplant activity rates over the period from 1999 to 2002. Major areas of concern are the high opposition rate and the decreasing quality of harvested grafts. Long-term analysis is underway to assess the impact of OCST on the quality of transplants performed in the catchment area

    The organizational model of the Interregional Transplant Agency Organizzazione Centro-Sud Trapianti

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    In Italy, all donation and transplant activities were officially disciplined in 1999 by the law 91 of April 1, 1999. This law enacted a coordinator-based model of transplantation, instituted the National Center for Transplantation (Centro Nazionale Trapianti-CNT), and endorsed the existing interregional transplant agencies (ITA), such as the Nord Italia Transplant program (NITp), the Associazione InterRegionale Trapianti (AIRT), and the Organizzazione Centro-Sud Trapianti (OCST). Within its borders each ITA has adopted its own organizational model; there is no overt centralized control exerted by the CNT according to the law 91/1999. The aim of the current work is to report on the organizational model adopted by OCST, the ITA gathering the Italian regions of Abruzzo, Basilicata, Calabria, Campania, Latium, Molise, Sardinia, Sicily, and Umbria
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