2,922 research outputs found
Teaching the virtual generation
No full textUsing Gioia and Brass’ 1986 article, “Teaching the TV Generation,” as a point of
departure for considering our current instructional environment, we focus on a relatively
recent development that once again has implications for our teaching pedagogies: that
we are, in fact, no longer teaching a verbal, nor even just a visual, but now a virtual
generation of students. Technological and social changes in the wider environment can
have major implications for teaching and learning pedagogies—i.e., optimal teaching
and learning occur when teaching styles align with learning styles. For that reason, we
consider some key learning principles in light of the learning styles of our current
generation of students, who are quite facile with virtual technologies. We argue that the
effective use of some electronic learning tools can provide useful and engaging means
for their education by addressing this generation’s preferences for virtual media while
also enabling student-directed interactivity (via online searches, games, simulations, etc.).
We first articulate the conceptual grounds for arguing that there has been another shift
in the teaching and learning environment we now face—which implies some necessary
adaptation of traditional learning principles. We then discuss: (a) some technologies and
applications (mainly Internet-based tools and videogames) that can facilitate the
convergence between virtual generation (V-Gen) preferences and classroom interactions;
(b) some guidelines for using these technologies to fulfil these learning principles and; (c)
some pitfalls that can occur and how to avoid them
A graphic method for depicting basin evolution and changes in the dominant hydrodynamic process from paleocurrent data
No full textPaleocurrent data measured on depositional elements and sedimentary structures (e.g., channels, cross-strata) are commonly utilized in the description of sedimentary strata. Paleocurrent data provide information about the depositional setting and in some cases can be useful for immediately detecting specific depositional processes (e.g., herringbone cross-strata for bimodal tidal currents). The typical graphical representation used to report paleocurrent data is the rose diagram. However, rose diagrams are not able to disclose all information contained in paleocurrent data, limiting the potentiality of such a representation method. In particular, there is presently no method to highlight changes in the paleogeographic configuration that can ultimately have an impact on the evolution of depositional processes and paleocurrent direction through time. Here, we present a graphic method that permits instant visualization of anomalies in paleocurrent distributions of the stratigraphic record that can be linked to changes in the paleogeography due to tectonic evolution or in the dominant hydrodynamic process. It is important to highlight that the proposed method does not aspire to replace rose diagrams but to provide an additional tool to be used before and in combination with rose diagrams in order to extrapolate as much information as possible from paleocurrent data
LC ANALYSIS OF LEUPROLIDE COMPONENT AMINO ACIDS IN INJECTABLE SOLUTION BY PHANQUINONE PRE-COLUMN DERIVATIZATION LABELLING PROCEDURE
No full textLuteinizing hormone-releasing hormone (LH-RH) is the blood-borne messenger between the hypothalamus and the anterior pituitary which controls reproductive function. The therapeutic usefulness of LH-RH would be limited because of its short biological half-life and also because of rapid inactivation in vivo. Rat ovulation studies revealed Leuprolide to be 50-80 times more active than LH-RH. Leuprolide is chemically defined as: p-Glu-L-His-L-Trp-L-Ser-L-Tyr-D-Leu-L-Leu-L-Arg-L-Pro-ethylamide.
An HPLC method was developed to analyze component amino acids in Leuprolide acetate (except Pro) using phanquinone derivatization and fluorometric detection. The amino acid analysis, indeed, presents difficulty because a weak detectability of the compounds. A fluorogenic derivatization prior to HPLC separation constitutes an effective and convenient technique to overcome the problem and to perform sensitive analyses. In previous studies (1,2) phanquinone reagent, devoid of significant native fluorescence, was found to react selectively with the primary amino function to give stable and highly fluorescent iminoquinols without degradation product forming.
The peptide was hydrolyzed with HCl 37% at reflux for 3 h and the resulting solution was derivatized and analyzed. The amino acid was found to react in 45 min at 50°C using 0.1 M phosphate buffer (pH 7). The RP-HPLC separations of the amino acid adducts were performed at 33±2°C on a Phenomenex Prodigy 5u ODS (250 x 3.2 mm i.d.) with gradient elution using a mobile phase consisting of a mixture A/B where A=0.05 M triethylamine phosphate buffer (pH 3) and B=methanol, at a flow rate of 0.4 ml/min. The fluorescence intensity at 460 nm (excitation at 400 nm) was monitored.
The proposed method, proved to be selective, sensitive, linear, precise and accurate and was applied with satisfactory results to the determination of Leuprolide acetate amino acids in commercial injection solution.
(1) R. Gatti, M.G. Gioia, A.M. Di Pietra, Anal. Chim. Acta 474 (2002) 11-20.
(2) R. Gatti, M.G. Gioia, P. Andreatta, G. Pentassuglia, J. Pharm. Biomed. Anal. (2003) in press
Long- and short-term erosion rates from the lower valley of the Tanagro River, southern Apennines
No full textTorre di MAre I. Ricerche archeologiche nell'insediamento medievale di Metaponto (1995-1999)
No full textCaratteri morfotettonici dell’area del Valico di Prestieri e dei Monti di Lauria (Appennino meridionale)
No full textAn alternative method of azimuthal data analysis to improve the study of relationships between tectonics and drainage networks: examples from southern Italy
No full textA detailed morphotectonic study of two intermontane basins located in the axial zone of the southern Apennines (Auletta and Valico di Prestieri basins) has been carried out to assess the relationships between Quaternary tectonics and fluvial network geometry. The comparison of morphological and structural features has been aided by an alternative method of morphotectonic data analysis based on the treatment of azimuthal populations by cumulative diagrams. The Auletta basin coincides with the present-day lower valley of the Tanagro River and is filled by upper Pliocene to lower-middle Pleistocene marine to continental sediments. Such deposits are tilted towards SW and dislocated by the 20 km-long NW–SE-trending fault bordering the huge carbonate morphostructure of the Alburni Mts. The complex evolution of the basin during the Quaternary has controlled the geometric arrangement of the main rivers of the area. The two major streams (i. e. Tanagro and Bianco rivers) appear to be structurally controlled by N120–140°-striking faults, as suggested by morphometric and geometrical (i.e. right-angled confluences and elbows, trellis-type fluvial pattern) characters of the net. In the southern flank of the valley, the preferred orientation of the I and II order fluvial channels (orthogonal to the Alburni Mts) indicates that the high relief and steep slopes of the Alburni positive morphostructure have been able to reduce the influence of the bedrock fracture pattern on the arrangement of minor streams. The Valico di Prestieri basin is a narrow trough located to the south of the Lauria Mts carbonate ridge in the western sector of the Calabria-Lucania border. This basin is filled by continental middle-upper Pleistocene alluvial deposits organized in several sedimentary bodies. Such depression was generated along a N120°-striking brittle shear zone and modified by subsequent extensional tectonics. Structural controls on the evolution of the fluvial net appear more marked here than in the Auletta basin. As a matter of fact, the minor channels of the Valico di Prestieri basin show a good geometric correspondence with the outcrop-scale fracture pattern of the Mesozoic carbonate which form the Lauria Mts. The major streams of this area follow the main N120–130°-trending tectonic lineaments. Relationships between Quaternary tectonics and fluvial network geometry are traditionally investigated by means of both classical morphostructural analysis – largely based on statistical treatments of azimuthal data – and morphometric calculation. In this study, orientation data have been represented through the azimuthal cumulative curve, a simple complementary method that facilitates the graphical plot and the morphotectonic interpretation of complex azimuthal datasets. Apart from resolving the well-known problems stressed by the use of rose diagrams, the method here adopted allows to display several statistical populations in the same graph, thus favouring the visual comparison between structural and geomorphological features and better emphasizing vertical-axis block rotations
Modeling Short-Term Landscape Modification and Sedimentary Budget Induced by Dam Removal: Insights from LEM Application
No full textSimulation scenarios of sediment flux variation and topographic changes due to dam removal have been investigated in a reservoir catchment of the axial zone of southern Italy through the application of a landscape evolution model (i.e.,: the Caesar–Lisflood landscape evolution models, LEM). LEM simulation highlights that the abrupt change in base level due to dam removal induces a significant increase in erosion ability of main channels and a strong incision of the reservoir infill. Analysis of the sediment dynamics resulting from the dam removal highlights a significant increase of the total eroded volumes in the post dam scenario of a factor higher than 4. Model results also predict a strong modification of the longitudinal profile of main channels, which promoted fluvial incision upstream and downstream of the former reservoir area. Such a geomorphic response is in Agreement with previous analysis of the fluvial system short-term response induced by base-level lowering, thus demonstrating the reliability of LEM-based analysis for solving open problems in applied geomorphology such as perturbations and short-term landscape modification natural processes or human impact
FIGURE 13A–D in New species from the nivicola group of Hypogastrura Bourlet, 1839 (Collembola, Poduromorpha, Hypogastruridae) from Canada
No full textFIGURE 13A–D. Hypogastrura ottawana sp. nov.: collophore and furcula; A, collophore chaetotaxy (lateral view), arrows indicate posterior chaetae; B, manubrium ventral chaetotaxy, empty circle is larger chaetae and black circle normal chaetae; C–D, dens and mucro: C, dorsal side; D, external side.Published as part of Cipola, Nikolas Gioia, 2020, New species from the nivicola group of Hypogastrura Bourlet, 1839 (Collembola, Poduromorpha, Hypogastruridae) from Canada, pp. 199-220 in Zootaxa 4786 (2) on page 214, DOI: 10.11646/zootaxa.4786.2.3, http://zenodo.org/record/387467
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