1,721,051 research outputs found

    Morphological evaluation of the placenta and fetal membranes during canine pregnancy from early implantation to term

    No full text
    To describe the histological changes of fetal adnexa throughout the physiological pregnancy, canine samples were obtained during natural delivery and caesarean section, as well as during ovariohysterectomy performed at any stage of undesired pregnancies (N=12). The first period of pregnancy (multiple samples collected at 10, 12, 14days) was consistent with pre- and peri-implantation events, i.e. apposition and initial invasion steps into the endometrium. The second period (multiple samples collected at 18, 38, 40, 45 days) was related to the development of extra-embryonic structures, placenta establishment and labyrinth formation. At the end of this period the maximum morphological complexity of the endotheliochorial placenta was achieved, characterized by complete erosion of the endometrial epithelium and underlying interstitium with exposure of maternal capillaries to the chorial cells. The third period of gestation (multiple samples collected at 50, 53, 57, 60, 63 days) was characterized by enhancement either of placental and extra-embryonic tissues

    The role of birth weight on litter size and mortality within 24h of life in purebred dogs : what aspects are involved?

    Full text link
    In humans, scientific evidence emphasizes the role of birth weight on neonatal welfare, morbidity and mortality. In canine species, defining normal ranges of birth weight is a harder issue due to a great morphological variability in size, body weight and breed. The aim of this study was to correlate birth weight with litter size and mortality within 24h of life in 789 pups from 140 litters of purebred dogs and to investigate the aspects that might affect these factors. Birth weight was influenced by maternal size, weight and age (P<0.001). The lightest pups were from toy sized or weighing up to 10kg bitches. Conversely, bitches aged 2-8 years whelped heavier pups than younger and older mothers. Birth weight was also related both to litter size, with heavier pups in smaller rather than in larger litters from medium sized bitches, and breed (P<0.05). Unexpectedly, birth weight did not differ between live born and stillborn pups. However, birth weight was lower in pups dying within 24h of life (P<0.05). High mortality of pups was related both to short pregnancies (P<0.05), also showing lighter litters (P<0.001), and to dystocic parturitions (P<0.001). Litter size was associated with parity, type and number of mating, and length of pregnancy (P<0.001). Low birth weight appears to predispose to early neonatal mortality suggesting a predominant role of the breed rather than size and weight in determining birth weight in pups

    Importanza delle aquaporine nell'equilibrio idrico dell'apparato riproduttore della cagna : bilanciamento dei fluidi oviduttali e possibile ruolo del meccanismo di imbibizione uterina

    No full text
    Il movimento di fluidi attraverso le membrane cellulari è rilevante in molti processi alla base della riproduzione. Il trasferimento passivo di acqua è facilitato dalla presenza di Aquaporine, proteine canale di membrana, la cui espressione negli organi riproduttori femminili muta con la fase funzionale. Lo studio immunoistochimico di quattro diverse isoforme di AQPs nella salpinge di cagna mira a dimostrare il loro coinvolgimento nelle funzioni secretorie e assorbenti atte a mantenere l’appropriato milieu oviduttale, fornendo l’ambiente migliore per la fecondazione e le prime fasi dello sviluppo embrionale. Anche la modulazione dell’imbibizione dei tessuti dell’utero correlata all’andamento degli ormonali steroidei e in rapporto al possibile processo di impianto embrionale, è rapportabile all’espressione di AQPs nei diversi tessuti
    corecore