12,539 research outputs found

    Richard-Sims/Sims_2023_OceanSODA-UNEXE: v1.0.0

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    This code relates to Sims, R. P., Holding, T. M., Land, P. E., Piolle, J.-F., Green, H. L., and Shutler, J. D.: OceanSODA-UNEXE: A multi-year gridded Amazon and Congo River outflow surface ocean carbonate system dataset, Earth Syst. Sci. Data, https://doi.org/10.5194/essd-2022-294, 2023

    Sims, Philander D. - An inaugural dissertation on typhoid fever

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    Handwritten inaugural dissertation on typhoid fever by Philander D. Sims, of Tennessee.Inaugural dissertation; no. 183

    Newton Sims on Victoria Creek (New Helena), Custer County, Nebraska

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    Photographer's annotation: 'House built by J. Merchant first in creek. Had underground passage dug to spring so if attacked by Indians could not be cut off from water supply, 1886.' Denise and Daryl Andersen identify the family as Issac Newton Sims, his two sons Theodore and George, and wife Clarinda. They lived in Anselmo in 192

    Special Supplement to Exhibit D: Traffic and Lydel Sims' "Assignment: Memphis"

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    Scanned by Jessica Shainker '18.Court Case Exhibit D - Transportation. Supplement to Exhibit D: Traffic, and Commercial Appeal articles by Lydel Sims on Memphis traffic

    Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS

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    Understanding the mechanism of interaction between pharmaceutical molecules (APIs) and impurities on crystal surfaces is a key concept in understanding purification and for the design of pharmaceutical crystallization processes. Several techniques may be used to study crystal surface properties, such as scanning electron microscopy (SEM) and X-ray photoelectron spectroscopy (XPS), which provide detailed imaging and elemental surface characterization. Time of flight secondary ion mass spectrometry (TOF-SIMS) is valuable in determining molecular identity and distribution. By combining TOF-SIMS, SEM, and optical (OM) and Raman microscopies, we can evaluate the usefulness of TOF-SIMS as a surface characterization technique for pharmaceutical crystals. 4-Nitrophenol has been selected as an impurity that can be incorporated during crystallization of acetaminophen (paracetamol). This study explores the distribution of impurity and its concentration on the different crystal faces of samples obtained by crystallization over a range of impurity loadings and supersaturation conditions. Raman maps of paracetamol single crystal faces were analyzed using the characteristic Raman peak intensity of 4-nitrophenol to identify regions where it accumulated; Raman maps of three single crystals produced in the presence of 4-nitrophenol using different crystallization procedures highlight how it can be difficult to detect very low concentrations of similar chemical species. In contrast, the 4-nitrophenol monoisotopic mass obtained via TOF-SIMS was shown to be detectable in all the three single crystals produced. This indicates that TOF-SIMS can be a valuable technique for single crystal impurity distribution mapping even when the impurity concentration is very low

    Monoportula P. A. Sims & D. M. Williams, nov. gen.

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    <i>Monoportula</i> P.A.Sims & D.M.Williams nov. gen. <p> <b>Registration</b>: http://phycobank.org/103661</p> <p> Type species:— <i>Monoportula uralensis</i> (Strelnikova) P.A.Sims & D.M.Williams nov. comb.</p> <p>Frustules cylindrical, valve face circular, flat. Valve face bordered by expanded marginal ridge separating it from vertical mantle. Areolae poroid, on valve face arranged in interrupted radial and sub-radial rows extending from off-centre hyaline area from which a stout spine extends. Scattered spinules cover valve face disturbing areolar arrangement. Mantle areolae in vertical rows situated between hyaline marginal ridge and hyaline valve margin. Mantle areolae covered by network of anastomosing costae. Internally areolae sunk in rows between hyaline ribs, areolae becoming more numerous towards valve margin. One (1) rimoportula present, its external opening through stout tube expanded at its summit, internally as slit between raised lips.</p>Published as part of <i>Williams, David M., Sims, Pat A. & Witkowski, Jakub, 2023, Notes on the rare Cretaceous species Syndetocystis uralensis Strelnikova leading to the description of a new monotypic genus Monoportula P. A. Sims et D. M. Williams nov. gen., pp. 219-224 in Phytotaxa 595 (2)</i> on page 220, DOI: 10.11646/phytotaxa.595.2.8, <a href="http://zenodo.org/record/7905940">http://zenodo.org/record/7905940</a&gt

    Sims, D. G.

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    D-SIMS and ToF-SIMS quantitative depth profiles comparison on ultra thin oxynitrides

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    To realise gate dielectrics in the present ULSI technology ultra thin oxynitrides are used. Nitrogen quantitative depth profiles are mandatory to characterise this material. Depth resolution is the key analytical parameter to obtain useful ultra thin oxides characterisation. To improve this resolution very low primary ion impact energy is required. In the present paper, we compare quantitative depth profiles carried out by dynamic-SIMS and ToF-SIMS, respectively. Dynamic-SIMS analyses have been performed using a Cameca 4-f and the new Cameca Sc-Ultra 300 instrument. Different impact energies and incidence angles were used in combination with MCs+ ion monitoring. The D-SIMS profiles at keV and sub keV primary beam impact energies, are discussed and compared with ToF-SIMS data obtained using a IONTOF IV instrument

    Psychometric Properties of a German Version of the “Satisfaction with Information about Medicines Scale” (SIMS-D)

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    ABSTRACTObjectiveThe aim of this study was to translate the Satisfaction with Information about Medicines Scale (SIMS) into German and test its psychometric properties in a German primary care setting. The SIMS was developed to assess the extent to which patients feel they have received enough information about their medicines.MethodsThree hundred seventy chronically ill patients were included in the study. The SIMS was translated to SIMS-D (German version) and evaluated in terms of acceptability, internal consistency, test–retest reliability, discriminant, and criterion-related validity.ResultsThe SIMS-D showed good internal consistency (Cronbach's α 0.92) and adequate test–retest reliability (Pearson's r > 0.7). Relationships to external criteria regarding medication management were acceptable (Spearman's ρ > 0.4). The SIMS-D was reasonably well accepted (return rate of 71%); however, older people produced more missing values when filling in the questionnaire.ConclusionsPreliminary evidence was given that the SIMS-D is a suitable instrument for measuring patient satisfaction with information about medicines in German primary care settings

    Patents, R and D, and the Stock Market Rate of Return

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    The purpose of this paper is to present and estimate a model which allows one to use the recently computerized U.S. Patent Office's data base to identify when and where changes in inventive output have occurred. The model assumes a firm which chooses a research strategy to maximize the expected discounted value of the net cash flows from its activities, and a stock market that evaluates this expectation at different dates (it is a version of the Lucas-Prescott, 1971, investment model). Patents are taken as an indicator of the output of the firm's research laboratories. These assumptions place a set of testable restrictions on the stochastic process generating patents, R&D, and the stock market rate of return on the firm's equity (the econometric framework used is that of a restricted index, or dynamic factor-analysis model [Sargent and Sims, 1977; Geweke, 1977b]). The data contain observations on these three variables for 120 firms over an eight year period. The model fits these data quite well and the final section reports on the implications of the parameter estimates.
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