99 research outputs found
CAPILLARY BLOOD AS A POTENTIAL ALTERNATIVE TO VENOUS BLOOD FOR COMPLETE BLOOD COUNT ANALYSIS FOLLOWING ACUTE EXERCISE IN MALES AND FEMALES
To compare the agreement and accuracy of complete blood counts (CBC) from capillary and venous blood sampled before and after acute aerobic exercise, 22 healthy men and women exercised for 40 minutes at 94% of ventilatory threshold. White blood cells increased by 51% (p<0.001) following acute exercise. There were no interactions of sampling site, time, and sex on CBC parameters. Lymphocytes, white blood cells, neutrophils, and hematocrit were slightly higher in venous blood after exercise. Lymphocytes, white blood cells, mixed cells, and neutrophils were strongly correlated at all timepoints (r>0.8, p<0.05) with good agreement, while mixed cells, hemoglobin, and hematocrit were strongly correlated at baseline (r>0.7, p<0.05), but showed weaker, non-significant correlations following exercise. These data suggest capillary sampling may be a useful alternative to venous sampling for measuring white blood cell counts following moderate intensity exercise, if differences between the sites fall within acceptable clinical limits.Master of Art
Endothelial Markers May Link Kidney Function to Cardiovascular Events in Type 2 Diabetes
SCINA: a case-based reasoning system for the interpretation of myocardial perfusion scintigrams
HOME-BASED EXERCISE IMPROVES QUALITY OF LIFE IN BREAST AND PROSTATE CANCER SURVIVORS: A META-ANALYSIS
Sasha Riley, Lauren C. Bates, Cameron K. Stopforth, Kaileigh Moertl, Kyle M. Edgar, Lee Stoner, FACSM, Erik D. Hanson, FACSM. University of North Carolina at Chapel Hill, Chapel Hill, NC.
Introduction and Objective: Breast (BCa) and prostate (PCa) cancer are the most common malignancies. While survival rates are high, many survivors experience decreased quality of life (QoL) during and after treatment. Supervised and group exercise improves QoL in cancer survivors. However, those living in a rural community and those with restrictions due to the COVID-19 pandemic can experience decreased access to exercise facilities. Home-based exercise may provide a feasible alternative for cancer survivors. The objective of this meta-analysis was to consolidate the literature investigating the effects of home-based exercise on QoL in BCa/PCa survivors. All study types were eligible for inclusion. Methods: Electronic databases were searched from inception to July 2021. Effect sizes were calculated using pre- and post-QoL values for the exercise group(s) for each article. To account for the use of different QoL measures between-studies, standardized mean differences (SMD) were calculated. Effects estimates were pooled using a 3-level model with restricted maximum likelihood estimation. An SMD of \u3c0.2, 0.2, 0.5, and 0.8 was defined as trivial, small, moderate, and large respectively. Results: Seventeen articles with 23 effects (n=639) met inclusion criteria. Home-based exercise led to small improvements in QoL [SMD=0.30, (95% CI 0.01, 0.60), p=0.042]. The QoL measurement type was a significant effect moderator (p=0.002), with the largest increase in QoL for the European Organization for Research and Treatment of Cancer QLQ-C30 [SMD=0.71 (95% CI 0.38, 1.03), p\u3c0.001]. Neither intervention duration (p=0.148) or type (p=0.795), cancer type (p=0.483), or age (p=0.279) were significant effect moderators. Conclusions: Home-based exercise improves QoL in BCa/PCa survivors, independent of cancer type, intervention duration and type, or age. Therefore, home-based exercise is an efficacious alternative option to improve QoL for BCa and PCa survivors who live in rural communities, who lack access to supervised training, or who cannot use gym facilities due to lasting pandemic safety restrictions
Evaluation of drug induced frequency dependent QT-prolongation using a flexible computer-based programmable stimulator
Developing a Systematic Procedure for the Assessment of Self-Defining Memories in Psychodynamic Therapy: Promise and Pitfalls
The innovative approach to assessing autobiographical memory narratives that Singer and Bonalume (2010) demonstrate in their case study of Cynthia is an ambitious expression of integrative psychotherapy research. It brings together the rich research findings on self-defining memories derived from laboratory studies and therapy case analyses, and applies these to the multimodal assessment situation in a psychotherapy program. Further, Singer and Bonalume's case of Cynthia is grounded in a truly "common factor" that is essential to most if not all psychotherapies: patient narrative expression. However, the integration of findings across different research studies still needs further elaboration to clarify and explore when they are consistent and when they are inconsistent with one another. In our commentary we critically assess the following issues associated with Singer and Bonalume's narrative memory coding system and its application to the case of Cynthia: (a) the utilization of narrative analyses for the identification of themes; (b) challenges inherent in establishing criteria for the identification of clinically important autobiographical memory narratives in therapy sessions; (c) the degree of integrative processing that takes place in narrative expression; and (d) the process of formulating inferences based on client narrative expression in assessment interviews versus therapy sessions. The commentary concludes with a discussion of promising future directions for narrative research in psychotherapy.
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