22,449 research outputs found
Port Argostoli
No full textsurveyed by lieutenant C. H. Simpson, r.n. assisted by lieut. J. C. Tancred & L. D. Penfold and sub-lieut. H. G. C. Somerville & E. A. Constable, r.n
Quantifying the roles of cell motility and cell proliferation in a circular barrier assay
No full textMoving fronts of cells are essential features of embryonic development, wound repair and cancer metastasis. This paper describes a set of experiments to investigate the roles of random motility and proliferation in driving the spread of an initially confined cell population. The experiments include an analysis of cell spreading when proliferation was inhibited. Our data have been analysed using two mathematical models: a lattice-based discrete model and a related continuum partial differential equation model. We obtain independent estimates of the random motility parameter, D, and the intrinsic proliferation rate, λ, and we confirm that these estimates lead to accurate modelling predictions of the position of the leading edge of the moving front as well as the evolution of the cell density profiles. Previous work suggests that systems with a high λ/D ratio will be characterized by steep fronts, whereas systems with a low λ/D ratio will lead to shallow diffuse fronts and this is confirmed in the present study. Our results provide evidence that continuum models, based on the Fisher–Kolmogorov equation, are a reliable platform upon which we can interpret and predict such experimental observations.Matthew J. Simpson, Katrina K. Treloar, Benjamin J. Binder, Parvathi Haridas, Kerry J. Manton, David I. Leavesley, D. L. Sean McElwain and Ruth E. Bake
Opening the can of worms: molecular analysis of schistosome populations
No full textThe Schistosomatidae are dioecious digenean parasites of the blood vascular system of vertebrates. Of the 13 genera within the family, only Sehistosoma is associated with humans and, of the mammalian blood flukes, this genus has achieved the greatest geographical distribution and diversification in terms of recognized species and definitive hosts parasitized. In this review, Dave Johnston, Emmanuel Dias Neto, Andy Simpson and David Rollinson consider some recent molecular research that either sheds light on the micro-evolutionary changes occurring within schistosome populations or provides insights into broader, macro-evolutionary questions.</p
Positron beam study of annealed silicon nitride films
No full textPositron annihilation spectroscopy has been used to study silicon nitride films grown by plasma-enhanced chemical vapor deposition and annealed at different temperatures. For both silicon-rich and nitrogen-rich films, the positron line shape (S) parameter increases after annealing for 15 min at temperatures up to 700-800 degrees C. This is understood in terms of the fact that removal of the hydrogen by annealing leads to the presence of unpassivated silicon dangling bond sites and vacancy complexes. Annealing at higher temperatures leads to a reduction in the S parameter, consistent with further hydrogen removal producing unpassivated N- sites. (C) 1996 American Institute of Physics.PT: J; CR: ASOKAKUMAR P, 1994, J APPL PHYS, V76, P4935 GOLDBERG RD, 1995, APPL SURF SCI, V85, P287 GOSSMANN HJ, 1992, APPL PHYS LETT, V61, P540 HABRAKEN FHP, 1991, LPCVD SILICON NITRID, P118 HAKVOORT RA, 1991, APPL PHYS LETT, V59, P1687 HAKVOORT RA, 1993, THESIS DELFT U TECHN HEYNS M, 1991, LPCVD SILICON NITRID, P82 LANDFORD WA, 1978, J APPL PHYS, V49, P2473 LANDFORD WA, 1992, NUCL INSTRUM METH B, V66, P65 LANDHEER D, 1995, J APPL PHYS, V78, P2568 LU Z, 1995, J VAC SCI TECHNOL 1, V13, P607 LYNN KG, 1989, CAN J PHYS, V67, P618 MITCHELL LV, 1990, AIP C P, V218, P121 PEROVIC DD, 1991, PHYS REV B, V43, P14257 RUBLOFF GW, 1990, VACUUM, V41, P790 SCHULTZ PJ, 1988, NUCL INSTRUM METH B, V30, P94 SCHULTZ PJ, 1988, PHYS REV LETT, V61, P187 SCHULTZ PJ, 1988, REV MOD PHYS, V60, P701 SIMPSON PJ, 1991, PHYS REV B, V44, P12180 SMITH DL, 1990, J ELECTROCHEM SOC, V137, P614 SMITH DL, 1990, MATER RES SOC S P, V165, P69; NR: 21; TC: 1; J9: J APPL PHYS; PG: 5; GA: TY119Source type: Electronic(1
Letter in letterbook from J. H. Woodward to D. B. Simpson, Jacobsburg, Ohio, January 24, 1882
No full textA document from an extensive collection spanning four generations of the Woodward family that operated merchant pig iron companies in West Virginia and Alabama. The collection begins with Stimpson Harvey Woodward (S. H. Woodward), a native of Massachusetts, who moved from Pittsburgh to Wheeling, West Virginia in 1852. He had interests in an iron company as early as 1852 in West Virginia and began Alabama operations in 1869. The family business continued in Alabama until the death of S. H. Woodward's great-grandson in 1965
Letter in letterbook from J. H. Woodward to D. B. Simpson, Bellaire, Ohio, February 8, 1882
No full textA document from an extensive collection spanning four generations of the Woodward family that operated merchant pig iron companies in West Virginia and Alabama. The collection begins with Stimpson Harvey Woodward (S. H. Woodward), a native of Massachusetts, who moved from Pittsburgh to Wheeling, West Virginia in 1852. He had interests in an iron company as early as 1852 in West Virginia and began Alabama operations in 1869. The family business continued in Alabama until the death of S. H. Woodward's great-grandson in 1965
Letter in letterbook from J. H. Woodward to D. B. Simpson, Jacobsburg, Ohio, January 28, 1882
No full textA document from an extensive collection spanning four generations of the Woodward family that operated merchant pig iron companies in West Virginia and Alabama. The collection begins with Stimpson Harvey Woodward (S. H. Woodward), a native of Massachusetts, who moved from Pittsburgh to Wheeling, West Virginia in 1852. He had interests in an iron company as early as 1852 in West Virginia and began Alabama operations in 1869. The family business continued in Alabama until the death of S. H. Woodward's great-grandson in 1965
The marriage record of Simpson, Joseph J. and Johnson, L. D. S
No full textMarriage license for L.D.S. Johnson and Joseph J. Simpson. T.H. Jandon was the officiant
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