825 research outputs found

    Agius, D

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    Seismic anisotropy indicates organised melt beneath the Mid-Atlantic Ridge aids seafloor spreading

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    Skip Nav Destination RESEARCH ARTICLE| AUGUST 04, 2023 Seismic anisotropy indicates organized melt beneath the Mid-Atlantic Ridge aids seafloor spreading J.M. Kendall; D. Schlaphorst; C.A. Rychert; N. Harmon; M. Agius; S. Tharimena Author and Article Information Geology (2023) 51 (10): 968–972. https://doi.org/10.1130/G51550.1 Article history Standard View Open thePDFfor in another window Cite Share Icon Share Permissions Abstract Lithospheric plates diverge at mid-ocean ridges and asthenospheric mantle material rises in response. The rising material decompresses, which can result in partial melting, potentially impacting the driving forces of the system. Yet the geometry and spatial distribution of the melt as it migrates to the ridge axis are debated. Organized melt fabrics can cause strong seismic anisotropy, which can be diagnostic of melt, although this is typically not found at ridges. We present anisotropic constraints from an array of 39 ocean-bottom seismometers deployed on 0–80 Ma lithosphere from March 2016 to March 2017 near the equatorial Mid-Atlantic Ridge (MAR). Local and SKS measurements show anisotropic fast directions away from the ridge axis, which are consistent with strain and associated fabric caused by plate motions with short delay times, δt (<1.1 s). Near the ridge axis, we find several ridge-parallel fast splitting directions, φ, with SKS δt that are much longer (1.7–3.8 s). This is best explained by ridge-parallel sub-vertical orientations of sheet-like melt pockets. This observation is much different than anisotropic patterns observed at other ridges, which typically reflect fabric related to plate motions. One possibility is that thicker sub-ridge lithosphere with steep sub-ridge topography beneath slower spreading centers focuses melt into vertical, ridge-parallel melt bands, which effectively weakens the plate. Associated buoyancy forces elevate the sub-ridge plate, providing greater potential energy and enhancing the driving forces of the plates

    A dual origin for Bcr-Abl gene translocation/fusion as dynamics of synergism of the hematopoietic stem cell and hemangioblast in chronic myeloid leukemia

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    Contextual BCR-ABL tyrosine kinase over-activity determines in formulated fashion the emergence of proliferation and anti-apoptosis that arise largely as derived phenomena of otherwise homeostatic mechanisms of the c-ABL gene within hematopoietic stem cells and hemangioblasts in the bone marrow. The ability to suppress almost completely, both in terms of phenotype and cytogenetically, the myeloid cell line expansion by imatinib mesylate is indicative of a phenomenon that depends strictly on the transformed status of the cell of origin in the chronic myeloid leukemia process. It is with relevance to complex participation of the dynamics of the fused BCR- ABL protein product that contextual conditioning of the cells of origin of the gene translocation further motivates the dimensional expansion of the transformed myeloid cell clones to increasing proliferative rates, thus leading to blast crisis as eventual loss of differentiating potential.peer-reviewe

    Performance evaluation of Wied Dalam (WDD) seismic station in Malta

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    The continual operation of a permanent seismograph, now exceeding a couple of decades in some cases, naturally involves changes of hardware and software over time. Nonetheless, the long-term, consistent performance of the seismic station, and the good quality of its data, is very important for national seismic studies investigating the local seismicity, and also important for the international seismological community researching regional tectonics and deep Earth structures. Here we investigate the data availability and quality of the currently only seismic station on Malta (WDD) since its installation in 1995, and establish spectral patterns in the seismic data that may be influenced by diurnal variations, seasonal weather changes, and/or site-specific settings. The results are important for the future deployment of permanent seismic stations on the Maltese islands, and for the analysis of local seismic hazard and ground motion studies

    Exploring the crop epigenome: a comparison of DNA methylation profiling techniques

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    COST (European Cooperation in Science and Technology) [CA19125]Agius DR, Kapazoglou A, Avramidou E, Baranek M, Carneros E, Caro E, Castiglione S, Cicatelli A, Radanovic A, Ebejer JP, Gackowski D, Guarino F, Gulyás A, Hidvégi N, Hoenicka H, Inácio V, Johannes F, Karalija E, Lieberman-Lazarovich M, Martinelli F, Maury S, Mladenov V, Morais-Cecílio L, Pecinka A, Tani E, Testillano PS, Todorov D, Valledor L, Vassileva

    Education in Family Medicine : What has been achieved?

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    Contents: Education... historical landmarks - Pierre Mallia; The Malta College of Family Doctors and the Royal College of General Practitioners - John V. Howard; The MRCGP [INT] Qualification and Programme - Adrian Freeman; Malta from the view of an External Development Advisor - Jeremy Stupple; The Specialist Training Programme in Family Medicine - Malta - Mario R. Sammut and Gunther Abela; Psychometrics – MCFD/MRCGP[INT] summative examination - Dominic Agius; Continued professional development - Philip Sciortino; The Diploma in Family Practice in retrospect - Pierre Mallia; Report on MCFD Assessment Course - Renzo De GabrieleThe mission of the Journal of the Malta College of Family Doctors (JMCFD) is to deliver accurate, relevant and inspiring research, continued medical education and debate in family medicine with the aim of encouraging improved patient care through academic development of the discipline. As the main official publication of the Malta College of Family Doctors, the JMCFD strives to achieve its role to disseminate information on the objectives and activities of the College.peer-reviewe

    Is-sisien ta' Dizzjunarju tal-lsien Malti [sic] ta' Michael Agius u aspetti mill-makrostruttura u l-mikrostruttura tiegħu

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    F'dan l-istudju se nagħti ħarsa kritika lejn il-manuskritt Dizzjunarju tal-Lsien Malti [sic] li, flimkien ma' xogħlijiet oħra, Michael Agius ippreżenta lil-Librerija tal-Università tà Malta fi-1978 (Ellul, Ħarsa 108). Fl-ewwel parti ta' din il-kitba se nirrapporta dak li sibt wara li għarbilt il-lista tal-kliem ewlieni (headwords) tà Agius u anke l-entrati nfushom u ngħaddi biex nagħmel ipoteżi dwar kienx hemm dizzjunarji oħra li Agius seta' sejjes tiegħu fuqhom u jekk iva liema setgħu kienu. Fit-tieni parti se nagħmel ftit kummenti kritiċi skont qafas għall-analiżi ta' xogħlijiet lessikografiċi (Ellul, Proposta 99-104). Għal raġunijiet prattiċi, nillimita ruħi għall makrostruttura u l-firxa tal-vokabolarju, kif ukoll għall-aspetti ewlenin tal-mikrostruttura: il-grammatika u d-definizzjonijiet.peer-reviewe

    Prescribing humour in healthcare : part 1

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    The most creative aspect of language is humour I and it is one of the most important topics in the study of communication. The healing power of humour and laughter has been recorded and used throughout history. Humour is universal and there are claims of very beneficial effects from the use of positive feelings and emotions associated with laughter. Bertrand Russell notes that -Laughter is the most inexpensive and most effective wonder drug. Laughter is a universal medicine". During last October and November, the author had the opportunity and pleasure to deliver an eight week course on 'Prescribing Humor in Health Care: And I ain't kiddin!' to health professionals. The course was very well organized and coordinated by the Mana Institute of Medical Education (MIME). Eighteen participants took part in course and professionals included doctors, nurses, physiotherapists, radiographers, psychotherapists, occupational therapists and speech language pathologists among others.peer-reviewe

    Becoming a young doctor : meeting Sophie Butler and Clare Holt

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    Becoming a doctor is a major life changing event for any medical student. Students grow into their new role over the first ‘foundation’ years. Here, a year after their graduation, a senior doctor talks with two junior doctors, who are his friends and colleagues, about their experiences over the first year of their career. The author Dr Mark Agius, a Psychiatrist in Bedford and Cambridge, England is working with a couple of FY2 Doctors, or rather, they have just become FY2 Doctors, a year ago they were still medical students. Their names are Sophie Butler and Clare Holt. He talks to them about what it felt like to stop being medical students and become Doctors and how it has felt over this last year.peer-reviewe
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