2,858,586 research outputs found
SPSS Syntax - Polish Verbs
No full textPsycholexical study on Polish verbs.
The syntax for SPSS allows the calculation of EFA solutions from 1 to 7
Revista Gestion I+D vol 1 N° 1
No full textRevista Gestion I+D Vol 1, No 1 julio - diciembre (2016) - Postgrado en Gestión de Investigación y DesarrolloEstadísticas de VisualizaciónVisualización Resumen 287 / Visualización Investigación 207 / Cantidad de descargas 207 - al 23-02-202
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Logarithmic variance profiles and the corresponding f-1 spectra of temperature fluctuations in turbulent Rayleigh-Bénard convection
No full textWe report experimental results for the temperature variance 2(z) and the corresponding frequency spectra P(f) in turbulent Rayleigh-Bénard convection (RBC) in a cylindrical sample of aspect ratioT= D/L = 1:00 (D = 1:12 m is the diameter and L = 1:12 m the height). The measurements were conducted in the Rayleigh-number range 1011 < Ra < 1:35 1014 and Pr ' 0:8. For Ra = 1:35x1014, 2(z) could be described well by a logarithmic dependence on the vertical position z in a range of z 1 < z < z 2 with z 1 ' 70 and z 2 = 0:1L. Here L=(2Nu) is the thickness of a thin thermal sublayer adjacent to the horizontal plate where the heat flux (denoted by the Nusselt number Nu) is carried mostly by thermal diffusion. In the log layer, we found that the temperature spectra had a significant frequency range over which P(f) f with close to 1. As Ra decreased, increased so that the log layer became thinner. At Ra = 2:05 1011, z 2 < z 1 and therefore there was no range for a log layer. Correspondingly, the temperature spectrum near the horizontal plate did not have the f1 scaling form either
The role of vitamin D in type 1 diabetes complications: a cross sectional analysis of the Pittsburgh EDC study
No full textBackground: It has been postulated that vitamin D deficiency may be associated with diabetic complications. A comprehensive analysis of microvascular and macrovascular complications, however, has not been conducted in patients with type 1 diabetes. Hence, we investigated the associations between vitamin D levels and the prevalence of microalbuminuria, overt nephropathy, impaired endothelial function, end stage renal failure, confirmed distal symmetric polyneuropathy, coronary artery disease and lower extremity arterial disease in individuals with type 1 diabetes.\ud
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Methods: We measured circulating 25(OH)D and 25(OH)D3 in 214 individuals with type 1 diabetes who participated in the 25 year clinical visit of the Pittsburgh Epidemiology of Diabetes Complications study of childhood onset type 1 diabetes (n=214, mean age = 51 years and median diabetes duration = 42 years). Cross-sectional associations of 25(OH)D and 25(OH)D3 with diabetic complications were assessed with multivariable logistic regression adjusted for diabetes duration, sex, BMI, season of visit, HbA1c, insulin dose per body weight, hypertension, HDL and non-HDL cholesterol, WBC count, estimated glomerular filtration rate and albumin to creatinine ratio, as appropriate.\ud
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Results: Fully adjusted models revealed that each 1 ng/ml increase in 25(OH)D was associated with 3% to 6% lower odds of microalbuminuria (OR=0.97, 95% CI=0.94, 0.99), impaired eGFR (OR=0.96, 95% CI=0.93, 0.99) and confirmed distal symmetric polyneuropathy (OR=0.94, 95% CI=0.90, 0.98). Similar results were found for 25(OH)D3. These vitamin D metabolites were not independently associated with overt nephropathy, end stage renal failure, coronary heart disease or lower extremity arterial disease.\ud
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Conclusions: In this cohort of middle-aged adults with type 1 diabetes, both higher 25(OH)D and 25(OH)D3 were related with a lower prevalence of early diabetic kidney disease and diabetic neuropathy, but not with advanced renal disease and macrovascular disease. For the interest of public health, it would be imperative to determine whether vitamin D levels can further predict the risk of developing these diabetic complications
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Characterization of a Mycobacterium Smegmatis Mutant that is Simultaneously Resistant to D-Cycloserine and Vancomycin.
No full textA mutant of Mycobacterium smegmatis has been isolated that is simultaneously resistant to both D-cycloserine (D-CS) and vancomycin. Genetic complementation with a PBP4 homolog restores sensitivity to both drugs. Resistance to D-CS and vancomycin in this mutant is most likely due to a novel mechanism involving peptidoglycan assembly at the cell surface
Estimating selection pressures on HIV-1 using phylogenetic likelihood models
No full textHuman immunodeficiency virus (HIV-1) can rapidly evolve due to selection pressures exerted by HIV-specific immune responses, antiviral agents, and to allow the virus to establish infection in different compartments in the body. Statistical models applied to HIV-1 sequence data can help to elucidate the nature of these selection pressures through comparisons of non-synonymous (or amino acid changing) and synonymous (or amino acid preserving) substitution rates. These models also need to take into account the non-independence of sequences due to their shared evolutionary history. We review how we have developed these methods and have applied them to characterize the evolution of HIV-1 in vivo. To illustrate our methods, we present an analysis of compartment-specific evolution of HIV-1 em) in blood and cerebrospinal fluid and of site-to-site variation in the gag gene of subtype C HIV-1. Copyright (C) 2008 John Wiley & Sons, Ltd
Lattice study of ((D)over-bar(1)D*)(+/-) near-threshold scattering
No full textIn this exploratory lattice study, low-energy near threshold scattering of the ((D) over bar D-1*)(+/-) meson system is analyzed using lattice QCD with N-f = 2 twisted mass fermion configurations. Both s-wave (J(P) = 0(-)) and p-wave (J(P) = 1(+)) channels are investigated. It is found that the interaction between the two charmed mesons is attractive near the threshold in both channels. This calculation provides some hints in the searching of resonances or bound states around the threshold of ((D) over bar D-1*)(+/-) system.National Science Foundation of China (NSFC) [11335001, 11275169, 11075167, 11105153, 11505132, 11261130311]; Deutsche Forschungsgemeinschaft (DFG); Scientific Research Program - Shanxi Provincial Education Department [15JK1348]SCI(E)[email protected]
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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