86,630 research outputs found
An Approach to the Electrical Resistive Tomography Based on Meshless Methods
No full textElectrical resistance tomography is a noninvasive diagnostic technique based on the identification of the conductivity profile inside a
control volume using injected low-frequency currents. Possible advantages in clinical applications coming from a numerical approach
based on the combination of meshless method and finite element method are discussed
Effect of anisotropy in estimation of brain sources and conductivities via coupled EEG and MEG
No full textPurpose: This paper proposes an approach for the coupled EEG-MEG data analysis that takes into account the
anisotropy of brain tissues and the different sensitivities of EEG and MEG measurements.
Design/methodology/approach: The study is carried out by using a combination of analytical and numerical methods. In
particular, where available, closed solutions are used to evaluate the numerical errors, while FEM models are used where
anisotropy and geometrical characteristics make analytical solutions not applicable.
Findings: The impact of tissues anisotropy on coupled EEG-MEG analysis has been assessed, and the effectiveness of
an approach based on smart exploitation of different EEG and MEG sensitivity to improve sources reconstruction has been
demonstrated numerically.
Research limitations/implications: The analysis has been carried out using a spherical head model, and on simulated data.
Practical implications: The proposed approach allows to improve the localization of equivalent sources for the description
of cellular brain activity.
Originality/value: The properties of objective functions used in brain sources reconstruction from EEG and MEG has been
investigated taking into account tissues anisotropy in the spherical symmetric case. In addition a formulation of the joint source
and tissues tensor conductivity estimation by exploiting simultaneously bioelectric and biomagnetic measurements based on
the complementary sensitivity of those measurements has been presented
Variations on the Author
No full text“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
HLA antigens in Italian patients with systemic lupus erythematosus: evidence for the association of DQw2 with the autoantibody response to extractable nuclear antigens
No full textIn order to verify the hypothesis that Italian patients with systemic lupus erythematosus (SLE) may be immunogenetically distinct from SLE patients born in other regions, we investigated the HLA class I and II antigens and their relation with the various autoantibodies characteristic of the disease in an Italian SLE population. Forty-four SLE patients were typed for HLA-A, -B, -C, -DR and -DQ antigens; sera from the same patients were tested for the presence of antibodies to the nuclear or cytoplasmic antigens Ro/SSA, La/SSB, Sm and RNP (ENA). Results of HLA typing showed that the frequencies of DR3 and DQw2 were increased in patients compared with controls. Analysis of the correlations between HLA antigens and anti-ENA antibodies showed that both DQw2 and DR3 were increased in patients with anti-Ro and/or antiLa antibodies, while in patients with anti-Sm and/or antiRNP antibodies the DQw2 and DR4 were found to be increased. Only DQw2 was found to be significantly increased in anti-ENA positive patients. These results might suggest that Italian patients with SLE are, at least in part, different from lupus patients living in other geographical areas and suggest the association of DQw2 with the autoantibody response to ENA in SLE
ACTIVATION OF DIACYLGLYCEROL KINASE alpha IS REQUIRED FOR VEGF-INDUCED ANGIOGENIC SISGNALING IN VITRO
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