1,354,171 research outputs found
NEW MEDIA IN TRADE SHOWS Support tools or dominant solutions for the future?
No full textSystematically defined in 1986, Trade Shows (TSs) still represent today a leading business and development instrument for the global and European economy. However, over the years, TSs have acquired new functions and new roles. This evolution also happened in light of the major socio-economic changes of the new millennium. In particular, the XX and XXI centuries brought with them important socio-economic changes, thus forcing trade shows to deal with the effect of the globalization phenomenon, the consequences of the 2008 crisis, and the advent of the new media. Faced with this background, the aim of the present book is to gain a deeper understanding of the adoption and use of the new media in the TSs context. In particular, the work intends to reach the following objectives: (i) analysis of the thirty-year evolution (1988-2018) of the trade show literature; (ii) identification of the main trends emerging from the more recent literature (2010-2018); (iii) exploration of the impact of new media (i.e., social media and virtual tools) in the trade show sector, especially from the organizers’ perspective. Notably, the focus on the organizer’s category represents an attempt to fill a specific research gap, emerged from the analysis of the existing TS literature, concerning the scant attention towards this stakeholders’ target
Lo scavo di Palazzo Legnani Pizzardi a Bologna: l'epigrafia anforica
No full text281
Rei CretariÆ RomanÆ FaVtorVm Ac ta 45, 2018
Gli scavi condotti tra il 2006 e il 2008 dalla Soprintendenza Archeologia, belle arti e paesaggio per la città metropolitana di
Bologna e per le province di MO, RE, FE nell’area cortilizia di Palazzo Legnani Pizzardi, nel primo suburbio meridionale di
Bononia, hanno portato alla luce, per l’età romana, una grande depressione che forse faceva parte dell’originario sistema
difensivo della colonia, e che, probabilmente a partire dall’età augustea, venne colmata sia da materiale ceramico che da
elementi derivanti da demolizioni di edifici anche di un certo pregio. In particolare, consistente è la presenza di anfore,
tra le quali si annoverano un doppio bollo su Lamboglia 2, otto su Dressel 2–4, nove su Dressel 6A e sette su Dressel 6B.
Tali marchi sono tutti riconducibili a manifatture adriatiche, principalmente settentrionali, e sono per lo più riferibili a un
periodo compreso tra l’età augustea e la prima età imperiale. Ad essi si aggiunge un titulus pictus su un’anfora Dressel
7–11 che menziona la mur(ia) hisp(ana).Between 2006 and 2008 the Soprintendenza Archeologia, belle arti e paesaggio per la città metropolitana di Bologna e per
le province di MO, RE, FE carried out an excavation in the courtyard of Palazzo Legnani Pizzardi, which in Roman times
was located in the first southern suburb of Bononia. As for the Roman period, a big hollow has been found, which probably
belonged to the original defence system of the colony; afterwards, perhaps since the Augustan age, the hollow was filled
with both ceramics and materials derived from the demolition of upmarket buildings. In particular, a considerable amount
of amphorae has been found, 25 of them bearing stamps: one on Lamboglia 2, eight on Dressel 2–4, nine on Dressel 6A and
seven on Dressel 6B amphorae. All these containers were produced in the Adriatic area, mainly in its northern part, and
are mainly dated from the Augustan age to the Early Imperial age. In addition to that, a Dressel 7–11 amphora has been
found, which bears a poorly preserved painted inscription mentioning the mur(ia) hisp(ana)
Global vs. Local: A Quantitative Study of Factors Influencing Italian Consumers’ Preference in the Purchase of Food Products
No full textPurpose: The study intends to expand the current literature on Italian consumers’ brand preferences between local vs. global alternatives in the specific Italian food sector.
Design/methodology/approach: This study draws on concepts largely investigated like cultural identity theory, consumer ethnocentrism, and product category involvement to examine the mechanisms that drive Italian consumers to prefer alternative local or global brands in the food sector. A non-hierarchical cluster analysis represents the core part of the quantitative research that involved 412 participants.
Findings: By confirming the validity of existing studies, the present paper contributes to the food consumption literature by testing a conceptual model that integrates previous research concepts, thus deepening the analysis of the factors affecting Italian consumers’ food brand preferences. The cluster analysis allowed for dividing Italian consumers into two distinguished groups with characteristics coherent inside the same group.
Research limitations/implications: This study emphasizes the key relevance of the investigated variables in the implementation of positioning and communication strategies aimed at meeting the needs of specific markets in which firms operate, and it highlights the importance of analyzing those variables together. The sample composed of Italian consumers did not allow the generalizability of the results. Furthermore, this study focuses on the narrow category of chocolate bar products. Therefore, this does not permit the results to be generalized to other food products.
Originality/value: The novel research is based on signaling theory that contributes to the local and global branding domains from the Italian perspective. This work is also the first to analyze the food sector and the importance that Italians attribute to their food products and traditions through a cluster analysis approach
Trade shows and new media presence: The TS organizers’ perspective
No full textBased on the complexity and the multiple facets characterizing the phenomenon of trade shows
(TSs), the starting objective of the present dissertation is to identify, through a descriptive and
analytical review process, the subject areas most dealt with by the papers published during the
last twenty years (1997-2017) and focused on the TS topic and to outline the main trends
emerging from the recent (2010-2017) TS literature. In a second phase of the work, two of the
four trends, identified by the review process, have been specifically deepened from the
organizers’ perspective. The focus on the TS organizers’ category represents an attempt to fill
a specific research gap, which emerged from the review, concerning the scant attention of the
TS literature towards this stakeholders’ target. The TSO perspective has been then adopted
(through the use of in-depth interviews directed to 38 European trade show organizers) with a
view to analyzing the implementation of the social media tools in the TS context and the reaction
to the virtual trade shows’ (VTSs) advent, by enriching in this way the literature studies focused
on the “TSs and new media” and “Virtual TSs” trends. The results of this dissertation make
different contributions to TS literature (systematization of all the business and management
articles, devoted to the trade show studies published between 1997 and 2017, analysis of the
evolution of the TS literature of the last twenty years, classification of the areas of study most
enhanced by the selected papers, identification of the main trends and the most studied TS
stakeholders’ perspectives emerging from the recent TS literature and construction of a possible
framework of synthesis) and to business management (elaboration of an index for the evaluation
of the social media popularity of the TS activities, identification of the main challenges for
exhibition managers who want to adopt social media in their communicative strategies,
identification of the need to develop a social media strategic orientation in synergy with the
realization of other specific actions, whose managerial importance emerged from the
specialized literature). The limitations, characterizing this dissertation, provide avenues for
future researches. More specifically, the present work paves the way for investigating the use
of social media in the trade show sector further, by investigating for example the effect of SM
usage for pre-show, at-show and post-show promotion on the achievement of sales objectives
set for a trade show. Future research could also analyze the effect of SM usage in trade shows
on the achievement of non-sales performance objectives, such as information gathering,
exhibition image building, relationship improvement and achievement of contacts. For what
concerns the other trends characterizing the TS context (relationship marketing,
internationalization process and experiential marketing) from the dissertation emerges, on one
side, the necessity to be skilled on each of them in order to remain competitive in the
contemporary and foreseeable trade show scenario and, on the other, the awareness that the
competitiveness of the TS sector is based on an integrate adoption of these trends and actions.
Starting from this assumption, in the future, it could be interesting to investigate the relational,
experiential and internationalization trends from the Italian TS organizers’ perspective, as well
as in comparison with the rest of Europe, in order to identify the highest performing strategic
trends and those that instead need managerial improvement
Global Start-ups and Born global Spin-offs: A Multiple Case study
No full textThe paper aims to identify and analyze the major critical success factors at the base of the rapid internationalization of three different types of Born Global (BG) firms, namely start-up, academic spin-off and company spin-off. Based on a case study analysis, the findings show that the entrepreneurs’ dynamic capabilities, their passion and propensity to take risks, previous international experiences, language skills, the presence of an experienced staff, the ability to nurture relationships and networks based on mutual trust and on the transfer of know-how represent the major key factors for internationalization. This study intends to strengthen the literature focused on the BG phenomenon. However, the empirical analysis was conducted on an exiguous number of enterprises, operating in the high-tech sectors and founded few years ago. In order to obtain more generalizable results, future research should also focus on companies active in the low-tech sectors and founded in less recent years
DISSECTION OF THE MECHANISMS CONTROLLING HIGH CONSTITUTIVE ACTIVITY OF HOUSEKEEPING AND TISSUE-SPECIFIC CIS-REGULATORY ELEMENTS
No full textThe genetic information is identical within the organism but the mechanisms by which different cell types achieve specialized functions interpreting the same set of instructions is not completely understood. It is now increasingly accepted that the combination of different genomic elements, both promoters and enhancers, favors the recruitment of different TFs, which in turn promotes the assembly of different pre-initiation complexes, guaranteeing heterogeneity in transcriptional outputs across different tissues. Nevertheless, the cis-regulatory elements and the transcriptional rules that control and maintain the expression of constitutively active genes are still poorly characterized. Specifically, whether the constitutive activity of promoters and enhancers relies on entirely distinct or instead shared regulators is unknown. By dissecting the cis-regulatory repertoire of macrophages, we found that the ELF subfamily of ETS proteins selectively bound within 60 bp from the transcription start sites of highly active housekeeping genes. ELFs also bound constitutively active, but not poised macrophage-specific enhancers and promoters. The role of ELFs in promoting constitutive transcription is suggested by multiple evidences: ELF sites enabled transcriptional activation by endogenous and minimal synthetic promoters; ELF recruitment was stabilized by the transcriptional machinery, and ELF proteins mediated recruitment of transcriptional and chromatin regulators to core promoters. These data indicate that a distinct subfamily of ETS proteins imparts high transcriptional activity to a broad range of housekeeping and tissue-specific cis-regulatory elements, which is consistent with the role of an ETS family ancestor in core promoter regulation in a lower eukaryote
Propriedades antialérgicas e antiinflamatórias da curina, um alcaloide bisbenzilisoquinolínico isolado de Chondrodendron platyphyllum (Menispermaceae)
No full textFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, BrasilAs doenças inflamatórias representam importantes problemas de saúde pública em termos de prevalência morbidade e mortalidade em todo o mundo. A asma alérgica é uma doença inflamatória crônica das vias aéreas, que resulta de uma resposta imune exacerbada contra antígenos comuns. A terapia antiinflamatória e antialérgica inclui o uso de fármacos que causam efeitos colaterais significantes ou não são efetivos em situações específicas, justificando a pesquisa de fármacos inovadores, seguros e eficazes. A curina é um alcaloide que atua como inibidor do influxo de cálcio, contudo as suas propriedades antialérgica e antiinflamatórias, bem como os efeitos tóxicos decorrentes do seu uso in vivo permanecem por serem caracterizadas. Este trabalho tem como objetivo caracterizar as atividades antialérgicas e antiinflamatórias da curina, bem como investigar a toxicidade induzida pelo tratamento oral com este alcaloide. Utilizando um modelo experimental de asma, nós demonstramos que a administração oral da curina inibiu significativamente o recrutamento e a ativação de eosinófilos e a AHR em animais desafiados com OVA, além de reduzir a produção de eotaxina e IL-13. O verapamil, um antagonista de canais de cálcio, apresentou propriedades antialérgicas semelhantes, e o pré- tratamento com a curina inibiu a resposta contráctil induzida por cálcio em anéis de traqueia ex vivo, sugerindo que o mecanismo pelo qual a curina exerce seus efeitos é através da inibição de uma resposta dependente de cálcio. A avaliação toxicológica mostrou que a curina administrada oralmente por 7 dias não induziu toxicidade evidente. A avaliação da atividade antiinflamatória e analgésica demonstrou que a curina inibiu a formação de edema da pata e a permeabilidade vascular, inibiu respostas nociceptivas na fase inflamatória, mas não na fase neurogênica, além de inibir a hiperalgesia induzida por carragenina
Em adição, a curina inibiu a produção de PGE2, in vitro, sem afetar a expressão de COX-2 em macrófagos estimulados com LPS. Os efeitos do tratamento com a curina foram semelhantes aos efeitos da indometacina, mas diferentes dos efeitos do tratamento com morfina, sugerindo que o efeito analgésico da curina não resulta da inibição direta da ativação neuronal, mas depende de mecanismos antiinflamatórias que, pelo menos em parte, resultam da inibição da produção de PGE2. Utilizando um modelo de pleurisia induzida por LPS, nós demonstramos que o tratamento oral com a curina inibiu significativamente o recrutamento de neutrófilos para o lavado pleural, associado com a inibição da produção de citocinas inflamatórias e de leucotrieno B4 no lavado pleural. A curina também inibiu a produção de TNF-\03B1, IL-1\03B2, IL-6 e NO por macrófagos estimulados com LPS in vitro, e o verapamil, apresentou efeitos inibitórios semelhantes sugerindo que os efeitos inibitórios que a curina exerce sobre a ativação dos macrófagos, podem estar associados com a inibição do influxo de cálcio. Em conclusão, a curina apresentou efeitos antialérgicos, antiinflamatórios e analgésicos, na ausência de toxicidade evidente, que estão associados com a inibição da ativação de leucócitos e da produção de mediadores inflamatórios, cujos mecanismos envolvem uma inibição de uma resposta dependente de cálcio, e portanto tem potencial para o desenvolvimento de fármacosInflammatory diseases are major public health problems in terms of prevalence of morbidity and mortality worldwide. Allergic asthma is a chronic inflammatory airway disease, which results from an exacerbated immune response against common antigens. The anti-inflammatory and anti-allergic therapy includes the use of drugs that cause significant side effects or are not effective under specific conditions, justifying the search for novel, safe and effective drugs. Curine is an alkaloid that acts as an inhibitor of calcium influx, but its anti-inflammatory and anti-allergic properties, as well as the toxic effects resulting from its administration in vivo remain to be elucidated. This study aims to characterize the anti-inflammatory and anti-allergic properties of curine as well as investigate the toxicity induced by the oral treatment with this alkaloid. Using an experimental model of asthma, we have demonstrated that orally administered curine significantly inhibited the recruitment and activation of eosinophils and AHR in mice challenged with OVA, besides reducing the production of eotaxin and IL-13. Verapamil, a calcium channel antagonist, showed similar anti-allergic properties and the pre-treatment with curine inhibited the calcium-induced tracheal contractile response ex-vivo, suggesting that the mechanism by which curine exerts its effects is through the inhibition of a calcium-dependent response. The toxicological evaluation showed that curine administered orally for 7 days did not induce significant toxicity. The evaluation of the analgesic and anti-inflammatory activities of curine demonstrated that it inhibited paw edema formation and vascular permeability, inhibited nociceptive responses in the inflammatory phase, but not in neurogenic phase, and inhibited carrageenan induced hyperalgesia
In addition, curina inhibited PGE2 production in vitro, without affecting the expression of COX-2 in macrophages stimulated with LPS. The effects of the treatment with curine were similar to the effects of indomethacin, but different from the effects of morphine treatment, suggesting that the analgesic effect of curine does not result from direct inhibition of neuronal activation, but instead, relies on anti-inflammatory mechanisms which at least in part, result from inhibition of PGE2 production. Using a model of LPS-induced pleurisy, we demonstrated that the oral treatment with curine significantly inhibited the recruitment of neutrophils into the pleural lavage, associated with inhibition of cytokine and leukotriene B4 production in the pleural lavage. Also, curine inhibited the production of TNF-\03B1, IL- 1\03B2, IL -6 and NO by macrophages stimulated with LPS in vitro, and verapamil had similar inhibitory effects ,suggesting that the inhibitory effects that curine exerts on macrophage activation may be associated with the inhibition of calcium influx. In conclusion, curine the presented anti-allergic, anti-inflammatory and analgesic effects in the absence of significant toxicity, which are associated with the inhibition of leukocyte activation and production of inflammatory mediators, whose mechanisms involve inhibition of a calcium-dependent response and as such, has the potential for drug developmen
I rinvenimenti numismatici dallo scavo del cimitero medievale ebraico di Bologna
No full textNella recente edizione complessiva dello scavo della necropoli medievale ebraica di via Orfeo a Bologna (CURINA–DI STEFANO 2019) manca lo studio delle monete e della tessera mercatile rinvenuti. L’obiettivo di questo contributo è proprio quello di colmare questa lacuna evidenziando i dati desumibili, ma anche le criticità che si possono incontrare in questo tipo di studio. Dopo un inquadramento dello scavo ci si soffermerà sulle monete e sulla tessera mercantile recuperate, mettendole in relazione alle stratigrafie di ritrovamento e, più in generale, a contesti assimilabili.In the recent excavation survey published on the medieval Jewish necropolis in via Orfeo, Bologna, there is no discussion of the coins and token that had been found. This contribution addresses the omission by highlighting the deducing data as well as the critical issues that can be encountered in this type of study. After laying out the excavation’s framework, the article turns its attention to the recovered coins and token, considering them in the stratigraphies in which they were found and in their broader historical contexts
Le mura di Ariminum in Palazzo Agolanti-Pedrocca.Indagine archeologica e restauro architettonico. Il restauro scientifico di Palazzo Agolanti-Pedrocca a Rimini (2008-2013)
No full textIl libro tratta dell'indagine archeologica e del restauro scientifico del Palazzo Agolanti-Pedrocca, edificio storico seicentesco situato nel centro della città di Rimini. La sua caratteristica saliente è l'inclusione di un tratto di mura urbiche romane del III secolo d.c.. Il contributo firmato dagli autori Alessandro Mori e Rossella Roversi, che hanno effettuato l'intervento in qualità di progettisti e direttori lavori, ricostruisce la storia del palazzo, ne analizza il degrado, descrive i criteri di intervento, le tecniche e le tecnologie adottate nel consolidamento e nel restauro scientifico dell'edificio e delle strutture rinvenute negli scavi archeologici. Si è curata anche la rassegna fotografica che chiude il volume
Unlocking destination cultural reputation: the role of sustainable on-site activity involvement as moderator
No full textPurpose – The study aims to provide a detailed definition of Destination Cultural Reputation while also
exploring its impact on tourist satisfaction through an investigation of the dynamics between these two
elements. Additionally, the potential moderating role of on-site engagement in sustainable activities has been
investigated, examining whether satisfaction prompts tourists to exhibit behaviors such as the intention to
return and recommend the cultural destination.
Design/methodology/approach – To achieve these objectives, a survey and a structural equation model,
based on a sample of 647 visitors to an important UNESCO World Heritage site (i.e. Urbino), have been
adopted.
Findings – Findings confirm tourists’ recognition of the destination’s cultural reputation, supporting its
relationship with visitor satisfaction. Additionally, tourist satisfaction is positively associated with destination
loyalty. However, on-site sustainable activities negatively moderate the relationship between destination
reputation and tourist satisfaction. This suggests that a favorable cultural reputation should align with quality
sustainable activities in the destination to prevent tourist dissatisfaction.
Practical implications – The paper offers valuable practical insights for destination managers and
policymakers aiming to enhance appeal and sustainability.
Originality/value – The study contributes to enhancing the understanding of the complex relationship
between reputation, satisfaction, and loyalty in cultural destinations. In addiction it measures the reputation of
tourist destination through the specific cultural dimension
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